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Tag Content
iUUCD ID IUUC-Oar-090206
Ensembl Protein ID ENSOARP00000003864.1
UniProt Accession W5P0B6; W5P0B6_SHEEP
Genbank Protein ID ENSOARP00000003864
Protein Name Uncharacterized protein
Genbank Nucleotide ID AMGL01058640
Gene Name UBR2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOARG00000003613.1 ENSOART00000003932.1 ENSOARP00000003864.1
ENSOARG00000003613.1 ENSOART00000003934.1 ENSOARP00000003866.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/N-recognin/N-domain 1.20e-38 131.3 227 302
E3 activity/RING/RING 7.50e-09 36.2 1115 1220
E3 activity/N-recognin/UBR-box 4.20e-31 107.5 97 167
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/N-recognin/N-domain
   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy++LfNDE+H+yeqviy+lqkA++++qkea++fat++d++GRr+v++G++++ce+ak+ i++n++++++ pLkV+v
   Q: 227  YYCMLFNDEVHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGEFQYCEQAKSIIVRNTSRQTK-PLKVQV 302
           9*********************************************************************.****98 PP
   

   E3 activity/RING/RING
   S: 1    CaiC......................................ledf......kdgplvlpCgHvfhadClqkw.............. 29
           C++C                                      ++++      ++g ++++CgH++ha+C+q++              
   Q: 1115 CILCqeeqevnaeskamvlaafvqrstvlskdrskfiqdpenYDPLfmhpdlSCGIHTGSCGHIMHAHCWQRYfdsvqakeqrrqqr 1201
           7777444444444444444444444444444444433333332222444444558999***************************** PP
   S: 30   ...pglknssskefrCPlC 45
              + +++++++ef+CPlC
   Q: 1202 lrlHTSYDVENGEFLCPLC 1220
           ******************* PP
   

   E3 activity/N-recognin/UBR-box
   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           +lCgrvfkvge +y+Cr+C+vd+t+vlC+eCf  ++H+dH+y++++sggggfCdCGdteAw++g++C+k++
   Q: 97   HLCGRVFKVGEPTYSCRDCAVDPTCVLCMECFLGSIHRDHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHE 167
           68******************************************************************996 PP
   
Organism Ovis aries
Protein Sequence
(Fasta)
MASELEPEVQ ALDRSLLECS AEETAGKWLQ ATDLTREVYQ HLAHYVPKIY CRGPNPFPQK 60
EDMLAHQVLL GPMEWYLCGE DPELGFSKLE QTNKPSHLCG RVFKVGEPTY SCRDCAVDPT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oar-090206|E3,N-domain;E3,RING;E3,UBR-box|Ovis aries
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCACCTGAAC TCCTGCTCAA GACCGACCGC CCCAGGCAGG GTGGTGGCTT TGCGCCCCAC 60
CTCCCCCCCG GGCCGTGGCG AGGCCGCTGC CCTCGGGGCG GCAGTAGCGG CGTCAGCGCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oar-090206|E3,N-domain;E3,RING;E3,UBR-box|Ovis aries
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR
PROSITE

PS51157--ZF_UBR
Pfam

PF02617--ClpS
PF02207--zf-UBR
SMART

SM00396--ZnF_UBR1
Gene Ontology

GO:0000785--C:chromatin
GO:0000151--C:ubiquitin ligase complex
GO:0070728--F:leucine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0071233--P:cellular response to leucine
GO:0006342--P:chromatin silencing
GO:0033522--P:histone H2A ubiquitination
GO:0007141--P:male meiosis I
GO:0032007--P:negative regulation of TOR signaling
GO:0007283--P:spermatogenesis
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000949 Aegilops tauschii 28.02 4.00e-19 91.30
IUUC-Aml-001876 Ailuropoda melanoleuca 83.15 0.00e+00 2669.00
IUUC-Atr-002501 Amborella trichopoda 29.01 3.00e-24 108.00
IUUC-Apl-003828 Anas platyrhynchos 84.62 0.00e+00 2969.00
IUUC-Aca-005189 Anolis carolinensis 84.02 0.00e+00 2976.00
IUUC-Aly-005901 Arabidopsis lyrata 32.72 1.00e-21 100.00
IUUC-Ath-007148 Arabidopsis thaliana 28.17 3.00e-20 95.50
IUUC-Ago-007946 Ashbya gossypii 23.14 1.00e-19 93.20
IUUC-Ani-009334 Aspergillus nidulans 23.56 7.00e-44 173.00
IUUC-Ame-011917 Astyanax mexicanus 72.51 0.00e+00 2457.00
IUUC-Bta-012768 Bos taurus 97.00 0.00e+00 3395.00
IUUC-Bdi-014635 Brachypodium distachyon 25.05 8.00e-27 117.00
IUUC-Bol-015669 Brassica oleracea 30.66 1.00e-26 116.00
IUUC-Bra-017776 Brassica rapa 30.66 3.00e-27 118.00
IUUC-Cel-018476 Caenorhabditis elegans 31.76 1.00e-78 288.00
IUUC-Cja-019797 Callithrix jacchus 91.32 0.00e+00 2510.00
IUUC-Cfa-020950 Canis familiaris 93.37 0.00e+00 3266.00
IUUC-Cpo-022385 Cavia porcellus 89.17 0.00e+00 3148.00
IUUC-Csa-024082 Chlorocebus sabaeus 92.57 0.00e+00 3237.00
IUUC-Cho-025029 Choloepus hoffmanni 83.38 0.00e+00 2105.00
IUUC-Cin-025148 Ciona intestinalis 35.25 2.00e-133 470.00
IUUC-Csv-026296 Ciona savignyi 31.60 2.00e-21 97.10
IUUC-Cne-026823 Cryptococcus neoformans 21.97 4.00e-34 141.00
IUUC-Dre-028343 Danio rerio 71.06 0.00e+00 2439.00
IUUC-Dno-030002 Dasypus novemcinctus 90.05 0.00e+00 1904.00
IUUC-Dor-030207 Dipodomys ordii 87.60 0.00e+00 1161.00
IUUC-Dse-031531 Dothistroma septosporum 24.00 1.00e-47 186.00
IUUC-Dme-031910 Drosophila melanogaster 32.86 0.00e+00 790.00
IUUC-Ete-033162 Echinops telfairi 80.80 0.00e+00 1317.00
IUUC-Eca-033454 Equus caballus 91.78 0.00e+00 3196.00
IUUC-Eeu-034783 Erinaceus europaeus 78.17 0.00e+00 1424.00
IUUC-Fca-036588 Felis catus 92.75 0.00e+00 3230.00
IUUC-Fal-036919 Ficedula albicollis 84.68 0.00e+00 2901.00
IUUC-Gmo-039698 Gadus morhua 67.96 0.00e+00 1580.00
IUUC-Gga-041123 Gallus gallus 85.89 0.00e+00 3019.00
IUUC-Gac-042622 Gasterosteus aculeatus 64.58 0.00e+00 2136.00
IUUC-Gma-043803 Glycine max 30.66 1.00e-22 103.00
IUUC-Ggo-045583 Gorilla gorilla 91.36 0.00e+00 3207.00
IUUC-Hsa-046343 Homo sapiens 91.44 0.00e+00 3192.00
IUUC-Hvu-047707 Hordeum vulgare 28.02 1.00e-18 89.40
IUUC-Kpa-049088 Komagataella pastoris 22.59 2.00e-39 158.00
IUUC-Lch-049649 Latimeria chalumnae 73.65 0.00e+00 2550.00
IUUC-Lpe-051516 Leersia perrieri 26.44 7.00e-29 124.00
IUUC-Loc-052818 Lepisosteus oculatus 73.81 0.00e+00 2587.00
IUUC-Laf-054142 Loxodonta africana 89.86 0.00e+00 3166.00
IUUC-Mcc-055677 Macaca mulatta 92.35 0.00e+00 3218.00
IUUC-Meu-056204 Macropus eugenii 64.26 0.00e+00 672.00
IUUC-Mtr-058538 Medicago truncatula 30.18 2.00e-24 109.00
IUUC-Mla-058963 Melampsora laricipopulina 25.40 5.00e-52 200.00
IUUC-Mga-059698 Meleagris gallopavo 86.03 0.00e+00 2995.00
IUUC-Mvi-060535 Microbotryum violaceum 24.60 3.00e-46 181.00
IUUC-Mmr-060901 Microcebus murinus 89.63 0.00e+00 3119.00
IUUC-Mdo-062014 Monodelphis domestica 88.38 0.00e+00 3115.00
IUUC-Mmu-063699 Mus musculus 86.73 0.00e+00 3043.00
IUUC-Mac-064773 Musa acuminata 29.97 1.00e-23 106.00
IUUC-Mpu-066153 Mustela putorius furo 93.54 0.00e+00 3264.00
IUUC-Mlu-068151 Myotis lucifugus 90.14 0.00e+00 3157.00
IUUC-Nle-069529 Nomascus leucogenys 92.46 0.00e+00 3233.00
IUUC-Opr-071107 Ochotona princeps 85.71 0.00e+00 1312.00
IUUC-Ont-072189 Oreochromis niloticus 65.62 0.00e+00 2123.00
IUUC-Oan-072893 Ornithorhynchus anatinus 86.05 0.00e+00 3027.00
IUUC-Ocu-074082 Oryctolagus cuniculus 89.46 0.00e+00 3147.00
IUUC-Opu-083202 Oryza punctata 28.23 1.00e-22 103.00
IUUC-Ola-087460 Oryzias latipes 64.49 0.00e+00 2113.00
IUUC-Oga-088432 Otolemur garnettii 90.59 0.00e+00 3206.00
IUUC-Ptr-091180 Pan troglodytes 91.27 0.00e+00 3197.00
IUUC-Pan-092375 Papio anubis 92.40 0.00e+00 3231.00
IUUC-Psi-093049 Pelodiscus sinensis 85.33 0.00e+00 2974.00
IUUC-Pma-094152 Petromyzon marinus 48.24 0.00e+00 662.00
IUUC-Pno-094877 Phaeosphaeria nodorum 23.10 2.00e-36 149.00
IUUC-Ppa-095715 Physcomitrella patens 34.24 2.00e-22 102.00
IUUC-Pfo-096524 Poecilia formosa 62.98 0.00e+00 1991.00
IUUC-Pab-097989 Pongo abelii 90.70 0.00e+00 3147.00
IUUC-Pca-100207 Procavia capensis 72.96 0.00e+00 2372.00
IUUC-Ppe-101802 Prunus persica 29.96 3.00e-23 105.00
IUUC-Pva-102538 Pteropus vampyrus 92.43 0.00e+00 1207.00
IUUC-Pgr-103372 Puccinia graminis 24.49 1.00e-49 193.00
IUUC-Ptt-103878 Puccinia triticina 24.31 1.00e-45 179.00
IUUC-Rno-105567 Rattus norvegicus 86.52 0.00e+00 2984.00
IUUC-Sce-106272 Saccharomyces cerevisiae 20.47 4.00e-21 98.20
IUUC-Sha-106980 Sarcophilus harrisii 87.90 0.00e+00 2973.00
IUUC-Spo-108183 Schizosaccharomyces pombe 24.58 4.00e-49 191.00
IUUC-Smo-108719 Selaginella moellendorffii 31.58 2.00e-25 112.00
IUUC-Sit-110716 Setaria italica 28.45 6.00e-27 117.00
IUUC-Sly-111286 Solanum lycopersicum 25.27 5.00e-26 114.00
IUUC-Sar-113332 Sorex araneus 83.77 0.00e+00 2106.00
IUUC-Sbi-114577 Sorghum bicolor 28.97 2.00e-27 119.00
IUUC-Ssc-115525 Sus scrofa 94.61 0.00e+00 2568.00
IUUC-Tgu-116943 Taeniopygia guttata 85.50 0.00e+00 3004.00
IUUC-Tru-117673 Takifugu rubripes 64.47 0.00e+00 2140.00
IUUC-Tsy-119032 Tarsius syrichta 88.88 0.00e+00 1757.00
IUUC-Tni-119987 Tetraodon nigroviridis 63.70 0.00e+00 2095.00
IUUC-Tca-121077 Theobroma cacao 28.92 6.00e-23 104.00
IUUC-Tvi-122272 Trichoderma virens 23.75 1.00e-49 192.00
IUUC-Tae-125616 Triticum aestivum 28.77 2.00e-25 112.00
IUUC-Tur-126562 Triticum urartu 30.62 1.00e-23 105.00
IUUC-Tme-127156 Tuber melanosporum 23.41 2.00e-45 179.00
IUUC-Tbe-128103 Tupaia belangeri 82.91 0.00e+00 1170.00
IUUC-Ttr-128253 Tursiops truncatus 89.12 0.00e+00 3069.00
IUUC-Vpa-130540 Vicugna pacos 90.00 0.00e+00 2932.00
IUUC-Vvi-131290 Vitis vinifera 30.71 5.00e-23 104.00
IUUC-Xtr-132690 Xenopus tropicalis 78.54 0.00e+00 2763.00
IUUC-Xma-133748 Xiphophorus maculatus 63.37 0.00e+00 1966.00
Created Date 25-Jun-2017

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