iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-068192

Ensembl Protein ID

ENSMLUP00000019281.1

UniProt Accession

G1Q6E8; G1Q6E8_MYOLU

Genbank Protein ID

ENSMLUP00000019281

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AAPE02004541

Gene Name

ING5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000029235.1	ENSMLUT00000025234.1	ENSMLUP00000019281.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.70e-09	37.1	187	234

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C  ewfH+aC+ l+   ++p+ + w+Cp+C +
   Q: 187  TYC-LCHQVSYGE--MIGCDNpdCPiEWFHFACVDLT---TKPKGK-WFCPRCVQ 234
           69*.*******99..*********99***********...999997.******87 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MATAMYLEHY LDSIENLPCE LQRNFQLMRE LDQRTEDKKA EIDILAAEYI STVKTLSPEQ 60
RVEHLQKIQS AYSKCKEYSD DKVQLAMQTY EMVDKHIRRL DADLARFEAD LKDKLEGSDF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGCCAGAG CGCGGCCGCG GACGAAGATG GCGACTGCCA TGTACTTGGA GCACTACCTG 60
GACAGTAAGC GCCCTCCCCC ACCCGTGTCC CCCGGGCCGT CGCCCGTGCA GGGCCCTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028638--ING5
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:2001235--P:positive regulation of apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002381	Ailuropoda melanoleuca	96.49	1.00e-111	395.00
IUUC-Atr-002906	Amborella trichopoda	33.33	1.00e-33	135.00
IUUC-Apl-003516	Anas platyrhynchos	91.67	9.00e-100	355.00
IUUC-Aca-005009	Anolis carolinensis	86.55	6.00e-112	396.00
IUUC-Ame-011879	Astyanax mexicanus	76.35	4.00e-105	373.00
IUUC-Bta-012590	Bos taurus	96.92	3.00e-116	410.00
IUUC-Bdi-014504	Brachypodium distachyon	34.98	6.00e-37	147.00
IUUC-Bra-017027	Brassica rapa	30.29	4.00e-29	121.00
IUUC-Cja-019518	Callithrix jacchus	96.25	4.00e-123	433.00
IUUC-Cfa-020620	Canis familiaris	98.33	8.00e-136	475.00
IUUC-Cpo-022085	Cavia porcellus	97.46	8.00e-119	419.00
IUUC-Csa-023421	Chlorocebus sabaeus	97.08	3.00e-120	424.00
IUUC-Csv-026288	Ciona savignyi	54.17	5.00e-74	270.00
IUUC-Dre-027588	Danio rerio	77.27	8.00e-105	372.00
IUUC-Eca-033493	Equus caballus	96.92	1.00e-120	425.00
IUUC-Fca-035635	Felis catus	95.45	3.00e-56	211.00
IUUC-Fal-036998	Ficedula albicollis	92.17	3.00e-114	404.00
IUUC-Fox-037925	Fusarium oxysporum	59.62	1.00e-19	90.50
IUUC-Gmo-039035	Gadus morhua	77.59	2.00e-103	368.00
IUUC-Gga-040578	Gallus gallus	92.50	1.00e-122	432.00
IUUC-Gac-042172	Gasterosteus aculeatus	75.52	4.00e-105	373.00
IUUC-Gma-044339	Glycine max	31.71	2.00e-32	132.00
IUUC-Hsa-045965	Homo sapiens	97.08	3.00e-120	424.00
IUUC-Lpe-050822	Leersia perrieri	36.48	4.00e-37	147.00
IUUC-Loc-052725	Lepisosteus oculatus	84.17	8.00e-106	375.00
IUUC-Mcc-055455	Macaca mulatta	96.07	5.00e-112	396.00
IUUC-Mtr-058089	Medicago truncatula	31.69	2.00e-34	139.00
IUUC-Mga-059312	Meleagris gallopavo	91.58	4.00e-99	353.00
IUUC-Mmr-061351	Microcebus murinus	96.04	8.00e-111	392.00
IUUC-Mdo-062282	Monodelphis domestica	95.42	1.00e-117	415.00
IUUC-Mmu-063201	Mus musculus	95.42	3.00e-123	434.00
IUUC-Mac-064625	Musa acuminata	33.98	8.00e-38	150.00
IUUC-Mpu-066302	Mustela putorius furo	97.92	6.00e-122	429.00
IUUC-Ont-072055	Oreochromis niloticus	78.42	6.00e-103	366.00
IUUC-Oan-073652	Ornithorhynchus anatinus	94.74	1.00e-113	402.00
IUUC-Ocu-073871	Oryctolagus cuniculus	95.02	3.00e-122	430.00
IUUC-Obr-076266	Oryza brachyantha	34.54	2.00e-36	145.00
IUUC-Ogl-077118	Oryza glaberrima	33.99	1.00e-34	139.00
IUUC-Oin-079049	Oryza indica	34.13	9.00e-35	140.00
IUUC-Oni-082218	Oryza nivara	34.13	9.00e-35	140.00
IUUC-Opu-084171	Oryza punctata	35.12	4.00e-34	138.00
IUUC-Ola-087103	Oryzias latipes	76.03	8.00e-97	346.00
IUUC-Oga-088066	Otolemur garnettii	86.12	1.00e-102	365.00
IUUC-Ptr-091665	Pan troglodytes	97.08	3.00e-120	424.00
IUUC-Pan-091875	Papio anubis	97.08	3.00e-120	424.00
IUUC-Psi-093904	Pelodiscus sinensis	94.37	7.00e-107	379.00
IUUC-Ppa-096009	Physcomitrella patens	34.77	4.00e-30	124.00
IUUC-Pfo-096981	Poecilia formosa	79.25	7.00e-103	366.00
IUUC-Ppe-101441	Prunus persica	35.20	7.00e-35	140.00
IUUC-Pva-102282	Pteropus vampyrus	92.50	5.00e-127	446.00
IUUC-Rno-105646	Rattus norvegicus	95.00	1.00e-122	431.00
IUUC-Sha-107031	Sarcophilus harrisii	93.91	9.00e-110	389.00
IUUC-Smo-109441	Selaginella moellendorffii	35.77	1.00e-41	162.00
IUUC-Sit-109827	Setaria italica	34.27	7.00e-35	140.00
IUUC-Sly-111750	Solanum lycopersicum	33.73	3.00e-33	134.00
IUUC-Stu-112250	Solanum tuberosum	33.73	3.00e-33	134.00
IUUC-Sbi-114826	Sorghum bicolor	34.57	8.00e-36	143.00
IUUC-Tgu-116837	Taeniopygia guttata	90.91	1.00e-113	402.00
IUUC-Tru-117974	Takifugu rubripes	76.86	3.00e-99	353.00
IUUC-Tni-120024	Tetraodon nigroviridis	76.35	1.00e-90	325.00
IUUC-Tca-121597	Theobroma cacao	34.43	3.00e-32	131.00
IUUC-Tae-123043	Triticum aestivum	34.25	1.00e-36	146.00
IUUC-Vvi-131487	Vitis vinifera	35.44	1.00e-33	135.00
IUUC-Xtr-132189	Xenopus tropicalis	84.52	2.00e-115	407.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence