iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088066

Ensembl Protein ID

ENSOGAP00000015514.1

UniProt Accession

H0XHC4; H0XHC4_OTOGA

Genbank Protein ID

ENSOGAP00000015514

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AAQR03188692

Gene Name

ING5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000034901.1	ENSOGAT00000029670.1	ENSOGAP00000015514.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.80e-09	37.6	187	234

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C  ewfH+aC+ l+   ++p+ + w+Cp+C++
   Q: 187  TYC-LCHQVSYGE--MIGCDNpdCPiEWFHFACVDLT---TKPKGK-WFCPRCTQ 234
           69*.*******99..*********99***********...999997.******97 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MATAMYLEHY LDSKRPAAPR LPPCLCRASF SPISSSDKKA EIDLLAAEYI STVKTLSADQ 60
RVEHLQKIQS AYSKCKEYSD DKVQLAMQTY EMVDKHIRRL DADLARFEAD LKDKMEGSDF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGACCG CCATGTACTT GGAGCACTAC CTGGACAGTA AGCGCCCTGC AGCCCCGCGC 60
CTGCCGCCCG TGCGCAGCCC TCCTCGCCGC AGCCCGACGC GCTCTAGGCA CCGCGCGCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028638--ING5
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:2001235--P:positive regulation of apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002381	Ailuropoda melanoleuca	89.24	1.00e-95	342.00
IUUC-Atr-002906	Amborella trichopoda	37.87	1.00e-28	119.00
IUUC-Apl-003516	Anas platyrhynchos	88.78	4.00e-94	336.00
IUUC-Aca-005009	Anolis carolinensis	75.31	2.00e-90	325.00
IUUC-Ame-011879	Astyanax mexicanus	68.70	4.00e-88	317.00
IUUC-Bta-012590	Bos taurus	88.79	1.00e-100	358.00
IUUC-Cja-019518	Callithrix jacchus	86.94	3.00e-106	377.00
IUUC-Cfa-020620	Canis familiaris	87.35	4.00e-110	390.00
IUUC-Cpo-022085	Cavia porcellus	87.14	4.00e-101	360.00
IUUC-Csa-023421	Chlorocebus sabaeus	87.35	3.00e-102	364.00
IUUC-Dre-027588	Danio rerio	67.61	3.00e-87	314.00
IUUC-Eca-033493	Equus caballus	85.20	2.00e-100	358.00
IUUC-Fca-035635	Felis catus	93.67	1.00e-45	176.00
IUUC-Fal-036998	Ficedula albicollis	82.06	7.00e-94	336.00
IUUC-Gmo-039035	Gadus morhua	68.70	6.00e-85	306.00
IUUC-Gga-040578	Gallus gallus	80.82	2.00e-102	364.00
IUUC-Hsa-045965	Homo sapiens	87.35	3.00e-102	364.00
IUUC-Loc-052725	Lepisosteus oculatus	74.29	4.00e-86	310.00
IUUC-Mcc-055455	Macaca mulatta	90.13	1.00e-96	345.00
IUUC-Mtr-058089	Medicago truncatula	39.26	9.00e-32	130.00
IUUC-Mga-059312	Meleagris gallopavo	89.60	7.00e-96	342.00
IUUC-Mmr-061351	Microcebus murinus	95.61	3.00e-95	341.00
IUUC-Mdo-062282	Monodelphis domestica	85.31	6.00e-99	353.00
IUUC-Mmu-063201	Mus musculus	84.49	2.00e-103	367.00
IUUC-Mpu-066302	Mustela putorius furo	87.35	4.00e-103	367.00
IUUC-Mlu-068192	Myotis lucifugus	86.12	7.00e-103	366.00
IUUC-Ont-072055	Oreochromis niloticus	68.98	3.00e-84	304.00
IUUC-Oan-073652	Ornithorhynchus anatinus	84.68	7.00e-98	349.00
IUUC-Ocu-073871	Oryctolagus cuniculus	86.18	6.00e-105	372.00
IUUC-Ola-087103	Oryzias latipes	68.42	2.00e-81	295.00
IUUC-Ptr-091665	Pan troglodytes	87.35	3.00e-102	364.00
IUUC-Pan-091875	Papio anubis	87.35	3.00e-102	364.00
IUUC-Psi-093904	Pelodiscus sinensis	90.78	1.00e-94	338.00
IUUC-Pva-102282	Pteropus vampyrus	82.04	3.00e-105	374.00
IUUC-Rno-105646	Rattus norvegicus	84.08	7.00e-103	366.00
IUUC-Sha-107031	Sarcophilus harrisii	87.44	2.00e-93	334.00
IUUC-Smo-109441	Selaginella moellendorffii	40.80	6.00e-35	140.00
IUUC-Tgu-116837	Taeniopygia guttata	81.61	2.00e-93	334.00
IUUC-Tru-117974	Takifugu rubripes	65.99	3.00e-82	297.00
IUUC-Tni-120024	Tetraodon nigroviridis	66.26	7.00e-76	276.00
IUUC-Vvi-131487	Vitis vinifera	38.18	2.00e-29	121.00
IUUC-Xtr-132189	Xenopus tropicalis	75.41	8.00e-95	339.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence