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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-064279
UUCD1 version UUC-MuM-01025
Ensembl Protein ID ENSMUSP00000066324.4
UniProt Accession Q9R1W3; B9EHC2; O08670; O08883; RN103_MOUSE
Genbank Protein ID BAA19795.1; BAA34912.2; AAI37625.1
Protein Name E3 ubiquitin-protein ligase RNF103; KF-1; RING finger protein 103; RING-type E3 ubiquitin transferase RNF103; Zinc finger protein 103
Genbank Nucleotide ID D76445; AB012161; BC137624
Gene Name Rnf103; Zfp103
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000052656.12 ENSMUST00000064637.10 ENSMUSP00000066324.4
ENSMUSG00000052656.12 ENSMUST00000114178.7 ENSMUSP00000109816.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarmiRNAMapRAID2
Post-translational Modifications (PTMs)
PhosphositePlusPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 4.20e-07 31.5 619 661
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplv..lpCgHvfhadClqkwpglknssskefrCPlCr 46
           C +Cle f++g l+  lpCgHvfh++C+ +w     ++ ++  CP+Cr
   Q: 619  CVVCLENFENGCLLmgLPCGHVFHQNCIVMW-----LAGGRHCCPVCR 661
           **********87776688*************.....89*********8 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Acts as an E2-dependent E3 ubiquitin-protein ligase, probably involved in the ER-associated protein degradation pathway.
 Acts as an E2-dependent E3 ubiquitin-protein ligase, probably involved in the ER-associated protein degradation pathway.
Protein Sequence
(Fasta)
MWLKLFFLLL YFLVLFVLAR FFEAIVWYET GIFATQLVDP VALSFKKLKT ILECRGLGYS 60
GLPEKKDVRE LVEKSGDLME GELYSALKEE EASESVSSTN FSGEMHFYEL VEDTKDGIWL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064279|E3,RING|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGGCTACAGC GGGTCCAGTG CTCTGGGGGC GACGGCCGCG GCCTGCAGAG GCGGCAGGGA 60
CGGTGGCCGC GGTTGGCGCG GCGCGTCCGC ACGGGGCTGG GCACCGCGCG GCTACGCAGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064279|E3,RING|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR012336--Thioredoxin-like_fold
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50089--ZF_RING_2
Pfam

PF13639--zf-RING_2
SMART

SM00184--RING
Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway
KEGG mmu:22644
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002130 Ailuropoda melanoleuca 94.57 0.00e+00 1208.00
IUUC-Apl-004099 Anas platyrhynchos 84.16 0.00e+00 1099.00
IUUC-Aca-004500 Anolis carolinensis 84.38 0.00e+00 1115.00
IUUC-Ame-011513 Astyanax mexicanus 70.62 0.00e+00 926.00
IUUC-Bta-012824 Bos taurus 94.12 0.00e+00 1234.00
IUUC-Bdi-014038 Brachypodium distachyon 49.12 2.00e-10 58.90
IUUC-Bol-015892 Brassica oleracea 51.11 4.00e-10 58.20
IUUC-Cja-019429 Callithrix jacchus 93.97 0.00e+00 1231.00
IUUC-Cfa-020110 Canis familiaris 94.42 0.00e+00 1242.00
IUUC-Cpo-021413 Cavia porcellus 82.41 0.00e+00 1051.00
IUUC-Csa-023111 Chlorocebus sabaeus 94.40 0.00e+00 1125.00
IUUC-Dre-027675 Danio rerio 71.25 0.00e+00 935.00
IUUC-Dno-029645 Dasypus novemcinctus 92.23 0.00e+00 1111.00
IUUC-Dor-030871 Dipodomys ordii 92.08 0.00e+00 773.00
IUUC-Ete-032670 Echinops telfairi 89.34 1.00e-172 599.00
IUUC-Eca-033322 Equus caballus 94.42 0.00e+00 1207.00
IUUC-Eeu-035071 Erinaceus europaeus 96.77 3.00e-150 525.00
IUUC-Fca-036356 Felis catus 94.42 0.00e+00 1239.00
IUUC-Fal-036861 Ficedula albicollis 84.55 0.00e+00 1117.00
IUUC-Gmo-039251 Gadus morhua 61.09 0.00e+00 751.00
IUUC-Gga-040659 Gallus gallus 86.06 0.00e+00 1118.00
IUUC-Gac-042187 Gasterosteus aculeatus 62.97 0.00e+00 782.00
IUUC-Ggo-044883 Gorilla gorilla 95.17 0.00e+00 1279.00
IUUC-Hsa-045756 Homo sapiens 95.17 0.00e+00 1251.00
IUUC-Hvu-047185 Hordeum vulgare 51.06 3.00e-10 57.80
IUUC-Itr-048705 Ictidomys tridecemlineatus 86.34 0.00e+00 1107.00
IUUC-Lch-049872 Latimeria chalumnae 78.79 0.00e+00 979.00
IUUC-Lpe-051679 Leersia perrieri 60.00 9.00e-11 62.40
IUUC-Loc-051795 Lepisosteus oculatus 75.08 0.00e+00 950.00
IUUC-Laf-053807 Loxodonta africana 93.67 0.00e+00 1227.00
IUUC-Mcc-054842 Macaca mulatta 93.36 0.00e+00 1225.00
IUUC-Meu-056570 Macropus eugenii 86.72 0.00e+00 1054.00
IUUC-Mga-059758 Meleagris gallopavo 86.11 0.00e+00 986.00
IUUC-Mvi-060247 Microbotryum violaceum 52.27 1.00e-10 62.00
IUUC-Mmr-061620 Microcebus murinus 91.30 2.00e-171 595.00
IUUC-Mdo-062398 Monodelphis domestica 83.43 0.00e+00 1092.00
IUUC-Mpu-065770 Mustela putorius furo 94.72 0.00e+00 1214.00
IUUC-Mlu-067764 Myotis lucifugus 91.28 0.00e+00 1208.00
IUUC-Nle-069363 Nomascus leucogenys 94.57 0.00e+00 1244.00
IUUC-Opr-070664 Ochotona princeps 92.75 0.00e+00 1215.00
IUUC-Ont-072466 Oreochromis niloticus 62.41 0.00e+00 809.00
IUUC-Oan-073047 Ornithorhynchus anatinus 92.43 0.00e+00 838.00
IUUC-Ocu-074240 Oryctolagus cuniculus 91.16 0.00e+00 1214.00
IUUC-Obr-076086 Oryza brachyantha 48.15 3.00e-10 57.80
IUUC-Olo-080618 Oryza longistaminata 49.06 3.00e-11 61.60
IUUC-Ome-081159 Oryza meridionalis 48.94 4.00e-11 58.90
IUUC-Ola-086352 Oryzias latipes 62.14 0.00e+00 754.00
IUUC-Oga-088582 Otolemur garnettii 94.42 0.00e+00 1238.00
IUUC-Oar-090324 Ovis aries 93.12 0.00e+00 1224.00
IUUC-Pan-092792 Papio anubis 94.72 0.00e+00 1243.00
IUUC-Psi-092964 Pelodiscus sinensis 88.67 0.00e+00 1130.00
IUUC-Pma-094186 Petromyzon marinus 52.78 0.00e+00 685.00
IUUC-Pfo-097169 Poecilia formosa 60.58 0.00e+00 785.00
IUUC-Pab-098549 Pongo abelii 94.87 0.00e+00 1244.00
IUUC-Pca-100113 Procavia capensis 87.34 0.00e+00 1038.00
IUUC-Pva-102543 Pteropus vampyrus 92.83 0.00e+00 777.00
IUUC-Rno-105676 Rattus norvegicus 98.20 0.00e+00 1243.00
IUUC-Sha-106596 Sarcophilus harrisii 91.56 0.00e+00 716.00
IUUC-Sly-111354 Solanum lycopersicum 46.67 2.00e-12 64.30
IUUC-Sar-113147 Sorex araneus 94.08 0.00e+00 1100.00
IUUC-Ssc-115585 Sus scrofa 93.21 0.00e+00 1196.00
IUUC-Tgu-117258 Taeniopygia guttata 84.55 0.00e+00 1117.00
IUUC-Tsy-119127 Tarsius syrichta 92.11 0.00e+00 1073.00
IUUC-Tur-126354 Triticum urartu 37.50 2.00e-09 54.70
IUUC-Tbe-128054 Tupaia belangeri 94.07 0.00e+00 1019.00
IUUC-Ttr-128931 Tursiops truncatus 97.32 0.00e+00 847.00
IUUC-Vpa-130826 Vicugna pacos 93.62 0.00e+00 1115.00
IUUC-Xtr-132828 Xenopus tropicalis 80.54 0.00e+00 1078.00
Created Date 25-Jun-2017

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