iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049709

Ensembl Protein ID

ENSLACP00000019231.2

UniProt Accession

H3BBG0; H3BBG0_LATCH

Genbank Protein ID

ENSLACP00000019231

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01032323

Gene Name

KLHL6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000016915.2	ENSLACT00000019364.2	ENSLACP00000019231.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	8.30e-21	74.4	64	127
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	4.60e-10	38.6	163	193

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dv+l+v+g+ef++h++vLaa+S +F+a+f ++l+e++ +++++ik++++e+++ ll++ Yt+k+
   Q: 64   TDVVLCVDGREFSCHRVVLAAASNYFRAMFCNDLKEKN-EEKIVIKGIDAESMQILLDYTYTSKV 127
           7************************************9.***********************997 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nc+gilr+Ad+++++ Lkd++++fi+++F
   Q: 163  PDNCVGILRLADTHCLHMLKDQVQNFIIQNF 193
           89****************************9 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MGDTVEMSTD KPCPSQQLQS KDCPRQMGDM VEKSSDGKVK FDDNGLATVL QVGLENLRLE 60
NSLTDVVLCV DGREFSCHRV VLAAASNYFR AMFCNDLKEK NEEKIVIKGI DAESMQILLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTTTTGCC GATTAAACAT GAGAGCATCC GAGGTGATGC TCTGGGCAAC GATATGGGAG 60
ATACTGTGGA GATGAGTACG GACAAGCCAT GCCCCTCACA ACAACTGCAA AGCAAGGACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR029851--KLHL6
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0050853--P:B cell receptor signaling pathway
GO:0002467--P:germinal center formation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001509	Ailuropoda melanoleuca	79.32	0.00e+00	1040.00
IUUC-Apl-003490	Anas platyrhynchos	82.06	0.00e+00	1085.00
IUUC-Aca-005136	Anolis carolinensis	81.40	0.00e+00	1025.00
IUUC-Ame-010886	Astyanax mexicanus	68.93	0.00e+00	857.00
IUUC-Bta-013473	Bos taurus	78.47	0.00e+00	1009.00
IUUC-Cja-018888	Callithrix jacchus	79.15	0.00e+00	1035.00
IUUC-Cpo-021761	Cavia porcellus	73.16	0.00e+00	939.00
IUUC-Csa-023206	Chlorocebus sabaeus	79.32	0.00e+00	1036.00
IUUC-Cin-025367	Ciona intestinalis	40.79	9.00e-134	470.00
IUUC-Csv-026076	Ciona savignyi	42.93	7.00e-129	454.00
IUUC-Dre-027948	Danio rerio	73.36	0.00e+00	914.00
IUUC-Dno-030045	Dasypus novemcinctus	79.32	0.00e+00	1040.00
IUUC-Dor-030839	Dipodomys ordii	72.48	0.00e+00	926.00
IUUC-Eca-033608	Equus caballus	79.15	0.00e+00	1015.00
IUUC-Eeu-034640	Erinaceus europaeus	78.14	0.00e+00	1036.00
IUUC-Fca-036065	Felis catus	79.48	0.00e+00	1043.00
IUUC-Fal-036949	Ficedula albicollis	82.32	0.00e+00	1064.00
IUUC-Fso-038219	Fusarium solani	38.10	4.00e-09	52.40
IUUC-Gmo-039661	Gadus morhua	59.34	0.00e+00	634.00
IUUC-Gga-040740	Gallus gallus	81.92	0.00e+00	1084.00
IUUC-Gac-042413	Gasterosteus aculeatus	62.58	0.00e+00	793.00
IUUC-Ggo-045167	Gorilla gorilla	79.32	0.00e+00	1037.00
IUUC-Hsa-046120	Homo sapiens	79.32	0.00e+00	1036.00
IUUC-Itr-047926	Ictidomys tridecemlineatus	79.32	0.00e+00	1040.00
IUUC-Loc-052239	Lepisosteus oculatus	84.92	0.00e+00	1005.00
IUUC-Laf-054511	Loxodonta africana	79.15	0.00e+00	1042.00
IUUC-Mcc-055109	Macaca mulatta	79.32	0.00e+00	1037.00
IUUC-Meu-056522	Macropus eugenii	67.23	7.00e-95	341.00
IUUC-Mga-060012	Meleagris gallopavo	80.91	0.00e+00	1060.00
IUUC-Mmr-061364	Microcebus murinus	78.66	0.00e+00	1031.00
IUUC-Mdo-063033	Monodelphis domestica	73.43	0.00e+00	912.00
IUUC-Mmu-063880	Mus musculus	77.49	0.00e+00	994.00
IUUC-Mlu-068233	Myotis lucifugus	78.47	0.00e+00	1030.00
IUUC-Opr-070638	Ochotona princeps	76.47	0.00e+00	716.00
IUUC-Ont-071960	Oreochromis niloticus	62.91	0.00e+00	803.00
IUUC-Oan-073406	Ornithorhynchus anatinus	75.37	0.00e+00	971.00
IUUC-Ocu-074612	Oryctolagus cuniculus	78.92	0.00e+00	1033.00
IUUC-Ola-087181	Oryzias latipes	60.00	0.00e+00	773.00
IUUC-Oga-088955	Otolemur garnettii	78.34	0.00e+00	1029.00
IUUC-Oar-089682	Ovis aries	78.63	0.00e+00	1009.00
IUUC-Ptr-090969	Pan troglodytes	79.32	0.00e+00	1037.00
IUUC-Pan-092289	Papio anubis	79.32	0.00e+00	1036.00
IUUC-Psi-093279	Pelodiscus sinensis	80.91	0.00e+00	1070.00
IUUC-Pab-097957	Pongo abelii	81.36	0.00e+00	805.00
IUUC-Pca-100619	Procavia capensis	78.34	0.00e+00	1038.00
IUUC-Pva-102533	Pteropus vampyrus	76.00	5.00e-166	577.00
IUUC-Pte-104106	Pyrenophora teres	40.85	2.00e-10	59.30
IUUC-Pyt-104515	Pyrenophora triticirepentis	38.03	2.00e-09	55.50
IUUC-Rno-106111	Rattus norvegicus	77.65	0.00e+00	1023.00
IUUC-Sha-106716	Sarcophilus harrisii	74.27	0.00e+00	958.00
IUUC-Tgu-116839	Taeniopygia guttata	81.24	0.00e+00	1071.00
IUUC-Tru-117792	Takifugu rubripes	61.80	0.00e+00	786.00
IUUC-Tsy-119609	Tarsius syrichta	70.51	1.00e-118	419.00
IUUC-Tni-119682	Tetraodon nigroviridis	60.82	0.00e+00	779.00
IUUC-Tme-127039	Tuber melanosporum	29.14	3.00e-12	67.80
IUUC-Tbe-127961	Tupaia belangeri	74.76	0.00e+00	940.00
IUUC-Ttr-128917	Tursiops truncatus	77.24	0.00e+00	841.00
IUUC-Vpa-130721	Vicugna pacos	81.09	0.00e+00	740.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence