iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054162

UUCD1 version

UUC-LoA-00119

Ensembl Protein ID

ENSLAFP00000002833.4

UniProt Accession

G3SSB3; G3SSB3_LOXAF

Protein Name

Uncharacterized protein

Gene Name

UBE3C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000003403.4	ENSLAFT00000003405.4	ENSLAFP00000002833.4
ENSLAFG00000003403.4	ENSLAFT00000034794.1	ENSLAFP00000019198.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	6.80e-62	210.1	726	964

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgr 86
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f++++++    +p+ ++ + +    ++++flGr+lgkal+++ 
   Q: 726  PDLKKRIRVHLLNahgldEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGD-SFARHYYFLGRMLGKALYENM 813
           689**********99**9************************************9999999999965.999****************** PP
   S: 87   lldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeY 173
           l++lp++++f+++llg+  ++++++l+++dpe+yk+l ++k++ e d+eelgl++t+   ++ lge++++eLk gG++ipVt +N+ +Y
   Q: 814  LVELPFASFFLSKLLGTsaDVDIHHLASLDPEVYKNLLFLKSY-EGDVEELGLNFTVV--NNDLGEAQVVELKFGGKDIPVTSANRIAY 899
           ****************9666889******************99.78999987777765..888************************** PP
   S: 174  vklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykg 237
           ++lv++yrl+++i++++ afr+G+ +v++le+l++F+++e+++li+G    i++edlk++t+y g
   Q: 900  IHLVADYRLNKQIRQHCLAFRQGLANVVNLEWLRMFDQQEIQVLISGAqVPISLEDLKSFTNYSG 964
           ************************************************899************76 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

EEKASLLHRT QEERRKREEE RRRLKNAIII QSFIRGYRDR KQQYSIQRSA FDRCADLSQS 60
GGTFPIASGS SLTLLVRQLL FFYKQDEDSK RLIWVCQNVV KYSCLFVKQL NGPERLTCLF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGAAAAGG CTTCTCTTTT ACATCGTACT CAGGAAGAAA GAAGAAAGAG AGAGGTAAAA 60
CAGCTTTGTG ATACTCTCTG TAGATAAGCT TTTTCCTATA GCGTTCAAAT AAACCTTGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT
PF00612--IQ

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001355	Ailuropoda melanoleuca	89.66	0.00e+00	1664.00
IUUC-Apl-003731	Anas platyrhynchos	87.50	0.00e+00	1649.00
IUUC-Aca-005248	Anolis carolinensis	85.63	0.00e+00	1646.00
IUUC-Ame-010769	Astyanax mexicanus	60.73	0.00e+00	862.00
IUUC-Bta-012841	Bos taurus	87.29	0.00e+00	1634.00
IUUC-Cel-018638	Caenorhabditis elegans	37.91	1.00e-61	231.00
IUUC-Cja-019743	Callithrix jacchus	88.93	0.00e+00	1667.00
IUUC-Cfa-021031	Canis familiaris	89.91	0.00e+00	1670.00
IUUC-Cpo-022401	Cavia porcellus	87.28	0.00e+00	1632.00
IUUC-Csa-024107	Chlorocebus sabaeus	90.80	0.00e+00	1685.00
IUUC-Cho-024750	Choloepus hoffmanni	80.75	0.00e+00	640.00
IUUC-Cin-025432	Ciona intestinalis	42.32	1.00e-83	303.00
IUUC-Dre-028196	Danio rerio	74.66	0.00e+00	1349.00
IUUC-Dno-029024	Dasypus novemcinctus	91.52	0.00e+00	1711.00
IUUC-Dor-030483	Dipodomys ordii	84.90	0.00e+00	630.00
IUUC-Dme-031946	Drosophila melanogaster	34.89	8.00e-148	518.00
IUUC-Ete-032240	Echinops telfairi	81.53	7.00e-166	578.00
IUUC-Eca-033828	Equus caballus	90.90	0.00e+00	1712.00
IUUC-Eeu-034604	Erinaceus europaeus	84.67	3.00e-125	442.00
IUUC-Fca-035907	Felis catus	88.93	0.00e+00	1677.00
IUUC-Fal-037389	Ficedula albicollis	87.07	0.00e+00	1667.00
IUUC-Gmo-039254	Gadus morhua	66.59	0.00e+00	1143.00
IUUC-Gga-040310	Gallus gallus	87.28	0.00e+00	1668.00
IUUC-Gac-042054	Gasterosteus aculeatus	68.89	0.00e+00	1197.00
IUUC-Ggo-045031	Gorilla gorilla	91.21	0.00e+00	1691.00
IUUC-Hsa-045880	Homo sapiens	91.11	0.00e+00	1690.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	81.75	0.00e+00	668.00
IUUC-Lch-050403	Latimeria chalumnae	78.62	0.00e+00	1513.00
IUUC-Loc-052218	Lepisosteus oculatus	77.81	0.00e+00	1443.00
IUUC-Mcc-055127	Macaca mulatta	90.90	0.00e+00	1687.00
IUUC-Meu-056187	Macropus eugenii	98.77	4.00e-93	336.00
IUUC-Mga-059581	Meleagris gallopavo	87.18	0.00e+00	1668.00
IUUC-Mmr-061360	Microcebus murinus	87.23	0.00e+00	1597.00
IUUC-Mdo-062194	Monodelphis domestica	87.69	0.00e+00	1674.00
IUUC-Mmu-064189	Mus musculus	87.07	0.00e+00	1658.00
IUUC-Mpu-066439	Mustela putorius furo	88.73	0.00e+00	1660.00
IUUC-Mlu-068228	Myotis lucifugus	85.33	0.00e+00	1623.00
IUUC-Nle-069687	Nomascus leucogenys	91.00	0.00e+00	1687.00
IUUC-Opr-070592	Ochotona princeps	75.97	7.00e-122	431.00
IUUC-Ont-071836	Oreochromis niloticus	74.97	0.00e+00	1380.00
IUUC-Oan-072800	Ornithorhynchus anatinus	87.69	0.00e+00	1665.00
IUUC-Ocu-074587	Oryctolagus cuniculus	91.52	0.00e+00	1700.00
IUUC-Ola-087209	Oryzias latipes	74.23	0.00e+00	1351.00
IUUC-Oga-088776	Otolemur garnettii	85.32	0.00e+00	1511.00
IUUC-Oar-089441	Ovis aries	86.27	0.00e+00	1610.00
IUUC-Ptr-091273	Pan troglodytes	91.00	0.00e+00	1688.00
IUUC-Pan-091981	Papio anubis	91.00	0.00e+00	1687.00
IUUC-Psi-093203	Pelodiscus sinensis	86.12	0.00e+00	1593.00
IUUC-Pma-094738	Petromyzon marinus	60.16	0.00e+00	1073.00
IUUC-Pfo-097511	Poecilia formosa	75.18	0.00e+00	1393.00
IUUC-Pab-098634	Pongo abelii	90.44	0.00e+00	1652.00
IUUC-Pca-100987	Procavia capensis	90.52	0.00e+00	729.00
IUUC-Pva-103034	Pteropus vampyrus	84.28	0.00e+00	1558.00
IUUC-Rno-105380	Rattus norvegicus	86.84	0.00e+00	1595.00
IUUC-Sha-107108	Sarcophilus harrisii	81.01	0.00e+00	1521.00
IUUC-Sar-113687	Sorex araneus	77.19	0.00e+00	852.00
IUUC-Ssc-116168	Sus scrofa	84.84	0.00e+00	755.00
IUUC-Tgu-116729	Taeniopygia guttata	86.98	0.00e+00	1657.00
IUUC-Tru-118068	Takifugu rubripes	73.89	0.00e+00	1357.00
IUUC-Tsy-118942	Tarsius syrichta	88.67	0.00e+00	662.00
IUUC-Tni-120732	Tetraodon nigroviridis	72.99	0.00e+00	1310.00
IUUC-Tbe-127351	Tupaia belangeri	77.22	0.00e+00	1369.00
IUUC-Ttr-129061	Tursiops truncatus	88.93	0.00e+00	1642.00
IUUC-Xtr-132094	Xenopus tropicalis	82.97	0.00e+00	1524.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence