iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csv-025995

Ensembl Protein ID

ENSCSAVP00000007653.1

UniProt Accession

H2YQP5; H2YQP5_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000004574.1	ENSCSAVT00000007751.1	ENSCSAVP00000007651.1
ENSCSAVG00000004574.1	ENSCSAVT00000007752.1	ENSCSAVP00000007652.1
ENSCSAVG00000004574.1	ENSCSAVT00000007753.1	ENSCSAVP00000007653.1
ENSCSAVG00000004574.1	ENSCSAVT00000007754.1	ENSCSAVP00000007654.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.70e-20	70.4	785	838

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            +vly++e+ ++ eL l++G  v +i+k+   +gW+kg  e +g+ G fP+ F+e+
   Q: 785  AKVLYNFEPRSQQELRLRAGQSVNIISKAGDGQGWWKG--ECQGQVGYFPAKFTEE 838
           689***********************************..9************985 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

TEVWRQCVHW LIETGVLPRD HKTCQRHGTL FDLAQTLRDG VILCNLLNII QPGAVDFNRI 60
NLRPQMLQFS CLQNIRIAVN SLSNVFRLPE IFQPGDLYNM TNFAQVLQVL SLLSHTPPSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTGAAGTGT GGAGACAGTG TGTCCACTGG CTGATCGAGA CTGGAGTTTT GCCGCGCGAC 60
CACAAAACCT GCCAACGTCA TGGCACTCTG TTCGACTTAG CCCAGACTTT GAGAGATGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain
IPR028530--Vav

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00307--CH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00401--SH2DOMAIN

SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001362	Ailuropoda melanoleuca	34.61	1.00e-134	472.00
IUUC-Apl-003262	Anas platyrhynchos	35.87	4.00e-137	480.00
IUUC-Aca-004477	Anolis carolinensis	35.20	2.00e-133	468.00
IUUC-Ani-009276	Aspergillus nidulans	22.57	1.00e-11	64.30
IUUC-Ame-011608	Astyanax mexicanus	36.00	2.00e-152	531.00
IUUC-Bta-012722	Bos taurus	34.57	2.00e-133	468.00
IUUC-Cel-018578	Caenorhabditis elegans	29.40	9.00e-68	250.00
IUUC-Cja-020009	Callithrix jacchus	36.61	2.00e-142	498.00
IUUC-Cfa-020768	Canis familiaris	37.30	5.00e-140	489.00
IUUC-Cpo-021543	Cavia porcellus	34.76	1.00e-106	379.00
IUUC-Csa-024204	Chlorocebus sabaeus	34.32	5.00e-134	470.00
IUUC-Cin-025115	Ciona intestinalis	67.82	0.00e+00	1136.00
IUUC-Cne-027023	Cryptococcus neoformans	23.74	1.00e-14	73.90
IUUC-Dre-028308	Danio rerio	34.82	1.00e-149	522.00
IUUC-Dno-029474	Dasypus novemcinctus	34.73	2.00e-137	481.00
IUUC-Dor-031014	Dipodomys ordii	31.52	4.00e-88	317.00
IUUC-Eca-033682	Equus caballus	37.30	2.00e-139	488.00
IUUC-Eeu-034719	Erinaceus europaeus	28.39	1.00e-51	196.00
IUUC-Fca-035629	Felis catus	37.07	1.00e-147	515.00
IUUC-Fal-036684	Ficedula albicollis	34.81	8.00e-136	476.00
IUUC-Gmo-039409	Gadus morhua	34.95	2.00e-130	458.00
IUUC-Gga-040999	Gallus gallus	36.27	5.00e-140	490.00
IUUC-Gac-041395	Gasterosteus aculeatus	36.17	3.00e-137	481.00
IUUC-Ggo-044558	Gorilla gorilla	34.90	3.00e-136	477.00
IUUC-Hsa-046208	Homo sapiens	35.01	2.00e-137	481.00
IUUC-Itr-048730	Ictidomys tridecemlineatus	36.59	3.00e-136	477.00
IUUC-Lch-049650	Latimeria chalumnae	37.80	2.00e-32	130.00
IUUC-Loc-052827	Lepisosteus oculatus	34.94	2.00e-146	511.00
IUUC-Laf-054537	Loxodonta africana	37.30	3.00e-145	507.00
IUUC-Mcc-055054	Macaca mulatta	35.12	1.00e-137	481.00
IUUC-Meu-056680	Macropus eugenii	37.66	9.00e-98	349.00
IUUC-Mpo-057433	Magnaporthe poae	23.90	1.00e-06	47.40
IUUC-Mga-060106	Meleagris gallopavo	35.75	3.00e-137	481.00
IUUC-Mmr-061118	Microcebus murinus	35.45	2.00e-137	481.00
IUUC-Mdo-061875	Monodelphis domestica	35.42	5.00e-138	483.00
IUUC-Mmu-063735	Mus musculus	35.31	2.00e-142	498.00
IUUC-Mac-065055	Musa acuminata	37.14	2.20e-01	28.50
IUUC-Mpu-065856	Mustela putorius furo	34.84	4.00e-135	473.00
IUUC-Mlu-067818	Myotis lucifugus	36.76	1.00e-139	488.00
IUUC-Nle-069863	Nomascus leucogenys	33.83	8.00e-129	452.00
IUUC-Opr-070372	Ochotona princeps	32.40	6.00e-80	290.00
IUUC-Ont-071945	Oreochromis niloticus	35.74	2.00e-146	511.00
IUUC-Oan-073384	Ornithorhynchus anatinus	33.92	1.00e-101	362.00
IUUC-Ocu-074194	Oryctolagus cuniculus	35.27	9.00e-139	486.00
IUUC-Ola-086336	Oryzias latipes	36.06	1.00e-137	482.00
IUUC-Oga-089104	Otolemur garnettii	37.30	3.00e-140	491.00
IUUC-Oar-089272	Ovis aries	35.27	3.00e-138	484.00
IUUC-Ptr-090507	Pan troglodytes	35.52	7.00e-137	479.00
IUUC-Pan-092325	Papio anubis	35.80	1.00e-138	485.00
IUUC-Psi-094021	Pelodiscus sinensis	35.71	2.00e-137	481.00
IUUC-Pma-094372	Petromyzon marinus	34.05	5.00e-93	333.00
IUUC-Pfo-096732	Poecilia formosa	35.16	2.00e-143	501.00
IUUC-Pab-098630	Pongo abelii	36.33	2.00e-137	481.00
IUUC-Pca-100295	Procavia capensis	35.02	2.00e-117	414.00
IUUC-Pva-102262	Pteropus vampyrus	34.82	2.00e-129	454.00
IUUC-Rno-105332	Rattus norvegicus	35.77	3.00e-138	484.00
IUUC-Sha-107325	Sarcophilus harrisii	35.31	3.00e-141	494.00
IUUC-Sar-113456	Sorex araneus	33.06	2.00e-127	448.00
IUUC-Ssc-115338	Sus scrofa	36.25	4.00e-125	440.00
IUUC-Tgu-116595	Taeniopygia guttata	34.69	9.00e-133	466.00
IUUC-Tru-117884	Takifugu rubripes	35.09	8.00e-141	492.00
IUUC-Tsy-119429	Tarsius syrichta	33.81	9.00e-71	259.00
IUUC-Tni-120548	Tetraodon nigroviridis	35.03	3.00e-126	444.00
IUUC-Tca-121489	Theobroma cacao	28.04	1.20e-01	30.40
IUUC-Tbe-127995	Tupaia belangeri	34.66	6.00e-53	201.00
IUUC-Ttr-128281	Tursiops truncatus	34.73	2.00e-134	471.00
IUUC-Xtr-132747	Xenopus tropicalis	37.11	1.00e-138	485.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence