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Tag Content
UUCD2 ID IUUC-Bta-013377
UUCD1 version UUC-BoT-01146
Ensembl Protein ID ENSBTAP00000002998.5
UniProt Accession E1BDG7; E1BDG7_BOVIN
Genbank Protein ID DAA22406.1
Protein Name Ubiquitin specific peptidase 28
Genbank Nucleotide ID DAAA02040315
Gene Name USP28; BOS_14391
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000002323.5 ENSBTAT00000002998.5 ENSBTAP00000002998.5
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 1.30e-57 195.6 161 651
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeef 84
           +GlkN+gNtC++ +v+Q+L+++pe+r+l+l+     +  e+++    ++++  ++++lq lf+ ++ s++k v+p++ l+ lk + ++ 
   Q: 161  VGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSyslpqNVLENCPSH-TEKRNIVFMQELQYLFALMMGSNRKFVDPSAALDLLKGAFRS- 247
           6******************************96555445555543.3678889******************************99987. PP
   S: 85   sgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            + +qqD++Ef++ lld le++++                     + +++ +k+++++++lF g++ ++ + +        +e+f +++
   Q: 248  PEEQQQDVSEFTHKLLDWLEDAFQL------------------AVNVNNPRNKSENPMVQLFYGTFLTEGIREGKPF--CNNETFGQYP 316
           799********************22..................23457899****************9888765555..45899***** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
           l+v+g +     +l++cLe  + e  +e    +  +   ++++  ++ +++klP+vL+++L+Rf+f+++ +++eki++k+efp+ + ++
   Q: 317  LQVNGYR-----NLDECLEGAMVEGDIE----LLPSD--HSVKYGQERWFTKLPPVLTFELSRFEFNQSLGQPEKIHNKLEFPQIIYMD 394
           *******.....99****7766666665....55544..456778899***************************************** PP
   S: 263  pfcts.................................................................................... 267
           +++ +                                                                                    
   Q: 395  RYMYRskelvrskrdcirklkeeikilqqkleryvkygsgparfplpdmlkyviefastkpasessasqsdacmteplssahcltsdlt 483
           *9999777888878777777777777777777777777777777777777777777777777766666666666666666666666666 PP
   S: 268  ......peekqke............................................................................ 274
                 +     e                                                                            
   Q: 484  skestsE-----Estsqeaegtfsssedsgrksrmaeqplkpprssvempahpaprtvtdeeinfvktclqrwrneieqdiqdlknsia 567
           5555541.....05555666777777777777777888888888888888888888888888888888888888999999999999999 PP
   S: 275  ................kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                           ++ Y+L+av+vH+G+++ GHY+ayv+n+ ++ Wl+++D +Vte+++ee ++++       +aY+l+Y 
   Q: 568  sttqtieqmycdpllrQVPYRLHAVLVHEGQANAGHYWAYVYNQPRQvWLKYNDISVTESSWEELERDSYggqrnVSAYCLMYI 651
           99999999*******9***************************99999*******************8879***9********6 PP
   
Organism Bos taurus
Protein Sequence
(Fasta)
MTAELQQDDA AGATDRHGSS CQMLLNQLRE ITGIQDPSFL HEALKASNGD ITQAVSLLTD 60
ERVKEPSQET AAEPSEEEGS AASKEELAKV IDLTHDSKDD LQAAIALSLL ESPKIQADGR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Bta-013377|DUB,USP|Bos taurus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGAGGGTGAC CCACGGAGGG GCGTCTCGGC CATGACTGCG GAGCTGCAGC AGGACGACGC 60
GGCCGGAGCG ACCGACCGCC ACGGCTCGGT GGGCCTCGCG GCGGCGAACG CGAACCGGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Bta-013377|DUB,USP|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
Gene Ontology

GO:0016604--C:nuclear body
GO:0043234--C:protein complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008283--P:cell proliferation
GO:0034644--P:cellular response to UV
GO:0000077--P:DNA damage checkpoint
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0016579--P:protein deubiquitination
GO:0007265--P:Ras protein signal transduction
GO:0031647--P:regulation of protein stability
GO:0010212--P:response to ionizing radiation
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG bta:508902
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001836 Ailuropoda melanoleuca 93.98 0.00e+00 2022.00
IUUC-Apl-004010 Anas platyrhynchos 69.46 0.00e+00 1473.00
IUUC-Aca-004741 Anolis carolinensis 58.64 0.00e+00 847.00
IUUC-Ang-009577 Aspergillus niger 38.00 2.00e-12 68.90
IUUC-Ate-010275 Aspergillus terreus 35.24 1.00e-11 66.20
IUUC-Cja-019977 Callithrix jacchus 93.07 0.00e+00 1978.00
IUUC-Cfa-020378 Canis familiaris 91.73 0.00e+00 1361.00
IUUC-Cpo-021817 Cavia porcellus 88.91 0.00e+00 1905.00
IUUC-Csa-023446 Chlorocebus sabaeus 91.21 0.00e+00 1360.00
IUUC-Cho-024717 Choloepus hoffmanni 82.84 0.00e+00 1221.00
IUUC-Csv-025911 Ciona savignyi 34.88 1.00e-148 520.00
IUUC-Cme-027167 Cyanidioschyzon merolae 32.49 7.00e-16 79.70
IUUC-Dre-028105 Danio rerio 55.87 0.00e+00 708.00
IUUC-Dno-029559 Dasypus novemcinctus 89.30 0.00e+00 1495.00
IUUC-Dor-030955 Dipodomys ordii 88.72 0.00e+00 1905.00
IUUC-Ete-032828 Echinops telfairi 80.83 0.00e+00 1156.00
IUUC-Eca-034300 Equus caballus 93.41 0.00e+00 1930.00
IUUC-Eeu-034458 Erinaceus europaeus 88.76 0.00e+00 1719.00
IUUC-Fca-035753 Felis catus 92.85 0.00e+00 2007.00
IUUC-Fal-037062 Ficedula albicollis 63.52 0.00e+00 887.00
IUUC-Gmo-039593 Gadus morhua 51.73 0.00e+00 1025.00
IUUC-Gga-040878 Gallus gallus 64.89 0.00e+00 1326.00
IUUC-Gac-041867 Gasterosteus aculeatus 55.15 0.00e+00 1123.00
IUUC-Ggo-045384 Gorilla gorilla 93.07 0.00e+00 1976.00
IUUC-Hsa-046277 Homo sapiens 93.25 0.00e+00 1983.00
IUUC-Itr-048276 Ictidomys tridecemlineatus 86.42 0.00e+00 1161.00
IUUC-Lch-049692 Latimeria chalumnae 65.73 0.00e+00 1392.00
IUUC-Laf-053808 Loxodonta africana 86.01 0.00e+00 1793.00
IUUC-Mcc-055473 Macaca mulatta 91.21 0.00e+00 1360.00
IUUC-Meu-056416 Macropus eugenii 73.15 0.00e+00 1503.00
IUUC-Mga-060011 Meleagris gallopavo 67.88 0.00e+00 1417.00
IUUC-Mmr-060720 Microcebus murinus 90.58 0.00e+00 1875.00
IUUC-Mdo-061955 Monodelphis domestica 79.41 0.00e+00 1734.00
IUUC-Mmu-063870 Mus musculus 85.69 0.00e+00 1862.00
IUUC-Mpu-066454 Mustela putorius furo 91.20 0.00e+00 1328.00
IUUC-Mlu-067487 Myotis lucifugus 87.31 0.00e+00 1843.00
IUUC-Nle-070044 Nomascus leucogenys 93.16 0.00e+00 1981.00
IUUC-Opr-070888 Ochotona princeps 96.75 1.00e-160 560.00
IUUC-Ont-072386 Oreochromis niloticus 53.93 0.00e+00 734.00
IUUC-Ocu-074523 Oryctolagus cuniculus 90.50 0.00e+00 1915.00
IUUC-Oga-088618 Otolemur garnettii 91.44 0.00e+00 1933.00
IUUC-Oar-089848 Ovis aries 97.60 0.00e+00 1414.00
IUUC-Ptr-091630 Pan troglodytes 92.64 0.00e+00 1506.00
IUUC-Psi-093422 Pelodiscus sinensis 64.77 0.00e+00 1385.00
IUUC-Pma-094250 Petromyzon marinus 52.27 8.00e-73 266.00
IUUC-Pfo-096466 Poecilia formosa 57.04 0.00e+00 758.00
IUUC-Pab-098337 Pongo abelii 93.25 0.00e+00 1979.00
IUUC-Pca-100901 Procavia capensis 76.34 0.00e+00 1594.00
IUUC-Pva-102226 Pteropus vampyrus 87.60 0.00e+00 1728.00
IUUC-Rno-105735 Rattus norvegicus 83.39 0.00e+00 1855.00
IUUC-Sha-107489 Sarcophilus harrisii 85.65 0.00e+00 1849.00
IUUC-Ssl-108532 Sclerotinia sclerotiorum 34.57 2.00e-09 58.20
IUUC-Ssc-115463 Sus scrofa 71.56 0.00e+00 1032.00
IUUC-Tgu-116609 Taeniopygia guttata 68.96 0.00e+00 1417.00
IUUC-Tru-117807 Takifugu rubripes 54.32 0.00e+00 1092.00
IUUC-Tsy-118971 Tarsius syrichta 86.42 0.00e+00 1238.00
IUUC-Tni-119983 Tetraodon nigroviridis 54.19 0.00e+00 1104.00
IUUC-Ttr-128887 Tursiops truncatus 89.46 0.00e+00 1877.00
IUUC-Vpa-130614 Vicugna pacos 93.03 0.00e+00 1518.00
IUUC-Xtr-132436 Xenopus tropicalis 62.29 0.00e+00 1285.00
Created Date 25-Jun-2017

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