iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004995

Ensembl Protein ID

ENSACAP00000002598.2

UniProt Accession

G1KB10; G1KB10_ANOCA

Protein Name

Uncharacterized protein

Gene Name

LATS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000002691.3	ENSACAT00000002664.3	ENSACAP00000002598.2
ENSACAG00000002691.3	ENSACAT00000030654.1	ENSACAP00000023235.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	6.80e-07	29.2	100	137

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLl 39
           + ++l++lv+ G+d+e a++aL ++ + ++eaA+ey+ 
   Q: 100  NRQMLQELVNVGCDQEMAIRALKQTgSRSIEAALEYIS 137
           669*********************************86 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MRPKTFPATT YSGNSRQRLQ EIREGLKQPT KSFSQGLPVG PGGKSSLDTK IVLGKDSARQ 60
QQLRPSTKFG PYQKALREIS ASLSPFANEL GTTSAAIEVN RQMLQELVNV GCDQEMAIRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCAGCTCTG CGATCCCGCC CGGCCCCGCC TCCTCGCTGG AATGCGAAGG GAGGGCGGTG 60
GAATGACGCC GGAGCCCCGG GGGTCACGTG GGGGCGAAAG GAATGCAAAC AATGTAGCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR000961--AGC-kinase_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS51285--AGC_KINASE_CTER
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase

SMART

SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0005829--C:cytosol
GO:0005815--C:microtubule organizing center
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0034613--P:cellular protein localization
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0030216--P:keratinocyte differentiation
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0018105--P:peptidyl-serine phosphorylation
GO:0043065--P:positive regulation of apoptotic process
GO:0046620--P:regulation of organ growth

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001960	Ailuropoda melanoleuca	72.94	0.00e+00	1642.00
IUUC-Apl-003521	Anas platyrhynchos	81.71	0.00e+00	1479.00
IUUC-Ame-011481	Astyanax mexicanus	62.72	0.00e+00	1301.00
IUUC-Bta-012618	Bos taurus	74.11	0.00e+00	982.00
IUUC-Cja-019430	Callithrix jacchus	72.88	0.00e+00	1559.00
IUUC-Cfa-020687	Canis familiaris	72.26	0.00e+00	1603.00
IUUC-Cpo-021985	Cavia porcellus	81.29	0.00e+00	1036.00
IUUC-Csa-023534	Chlorocebus sabaeus	90.89	0.00e+00	952.00
IUUC-Dre-027538	Danio rerio	63.13	0.00e+00	1314.00
IUUC-Dno-029126	Dasypus novemcinctus	74.23	0.00e+00	1670.00
IUUC-Dor-030172	Dipodomys ordii	70.86	0.00e+00	1349.00
IUUC-Eca-033868	Equus caballus	74.57	0.00e+00	1607.00
IUUC-Eeu-034881	Erinaceus europaeus	61.18	0.00e+00	1209.00
IUUC-Fca-036203	Felis catus	70.09	0.00e+00	1483.00
IUUC-Fal-036668	Ficedula albicollis	80.85	0.00e+00	1853.00
IUUC-Gmo-039195	Gadus morhua	84.81	0.00e+00	782.00
IUUC-Gac-041789	Gasterosteus aculeatus	62.17	0.00e+00	1224.00
IUUC-Ggo-044904	Gorilla gorilla	72.05	0.00e+00	1523.00
IUUC-Hsa-046254	Homo sapiens	73.69	0.00e+00	1531.00
IUUC-Itr-047948	Ictidomys tridecemlineatus	72.14	0.00e+00	1357.00
IUUC-Lch-050079	Latimeria chalumnae	70.04	0.00e+00	1567.00
IUUC-Loc-052265	Lepisosteus oculatus	81.57	0.00e+00	897.00
IUUC-Laf-053806	Loxodonta africana	74.57	0.00e+00	1660.00
IUUC-Mcc-055253	Macaca mulatta	73.94	0.00e+00	1557.00
IUUC-Meu-056509	Macropus eugenii	83.74	0.00e+00	813.00
IUUC-Mga-059600	Meleagris gallopavo	81.99	0.00e+00	1878.00
IUUC-Mmr-061586	Microcebus murinus	72.73	0.00e+00	1497.00
IUUC-Mdo-062126	Monodelphis domestica	76.56	0.00e+00	1701.00
IUUC-Mmu-063164	Mus musculus	68.78	0.00e+00	1401.00
IUUC-Mpu-065992	Mustela putorius furo	73.56	0.00e+00	1651.00
IUUC-Mlu-067728	Myotis lucifugus	67.71	0.00e+00	1430.00
IUUC-Nle-069546	Nomascus leucogenys	73.78	0.00e+00	1537.00
IUUC-Opr-070872	Ochotona princeps	71.00	0.00e+00	1462.00
IUUC-Ont-072296	Oreochromis niloticus	60.44	0.00e+00	1240.00
IUUC-Ocu-074068	Oryctolagus cuniculus	70.75	0.00e+00	1479.00
IUUC-Ola-086756	Oryzias latipes	59.44	0.00e+00	1222.00
IUUC-Oga-089066	Otolemur garnettii	72.39	0.00e+00	1568.00
IUUC-Oar-090416	Ovis aries	78.25	0.00e+00	966.00
IUUC-Ptr-091247	Pan troglodytes	73.78	0.00e+00	1558.00
IUUC-Pan-092438	Papio anubis	73.85	0.00e+00	1555.00
IUUC-Psi-093920	Pelodiscus sinensis	80.53	0.00e+00	1844.00
IUUC-Pfo-096334	Poecilia formosa	84.27	0.00e+00	897.00
IUUC-Pab-098452	Pongo abelii	72.77	0.00e+00	1538.00
IUUC-Pca-101081	Procavia capensis	69.24	0.00e+00	1516.00
IUUC-Pva-103036	Pteropus vampyrus	76.06	0.00e+00	759.00
IUUC-Rno-105102	Rattus norvegicus	68.35	0.00e+00	1386.00
IUUC-Sha-106917	Sarcophilus harrisii	76.83	0.00e+00	1727.00
IUUC-Sar-113711	Sorex araneus	67.82	0.00e+00	1336.00
IUUC-Tgu-116553	Taeniopygia guttata	82.59	0.00e+00	1842.00
IUUC-Tru-118069	Takifugu rubripes	86.12	0.00e+00	907.00
IUUC-Tni-120617	Tetraodon nigroviridis	60.73	0.00e+00	1202.00
IUUC-Ttr-129256	Tursiops truncatus	76.03	0.00e+00	1021.00
IUUC-Xtr-132593	Xenopus tropicalis	72.52	0.00e+00	1600.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence