iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091247

Ensembl Protein ID

ENSPTRP00000009705.3

UniProt Accession

H2Q796; H2Q796_PANTR

Genbank Protein ID

JAA04139.1; JAA25873.1; JAA44451.1

Protein Name

LATS, large tumor suppressor, homolog 2

Genbank Nucleotide ID

AACZ03091906; GABD01007227; GABE01000288

Gene Name

LATS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000005691.3	ENSPTRT00000010490.3	ENSPTRP00000009705.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	99.45	0.00e+00	2010.00	IUUC-Hsa-046254

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MRPKTFPATT YSGNSRQRLQ EIREGLKQPS KSSVQGLPAG PNSDTSLDAK VLGSKDATRQ 60
QQQMRATPKF GPYQKALREI RYSLLPFANE SGTSAAAEVN RQMLQELVNA GCDQEMAGRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCGTGGAA TGCCAACAAT GTAGCGAATG TCCCACTTGG GTCTGCGCTT TGGAACCGCG 60
GCGTGAGCGC CCCGGGAAGA TGGAGCAGTC GCCGTCCACG CCACCGCCGC CGCCCGGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR000961--AGC-kinase_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS51285--AGC_KINASE_CTER
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase

SMART

SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0005829--C:cytosol
GO:0005815--C:microtubule organizing center
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0034613--P:cellular protein localization
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0001827--P:inner cell mass cell fate commitment
GO:0001828--P:inner cell mass cellular morphogenesis
GO:0030216--P:keratinocyte differentiation
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0018105--P:peptidyl-serine phosphorylation
GO:0043065--P:positive regulation of apoptotic process
GO:0046620--P:regulation of organ growth

KEGG

ptr:452466

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001960	Ailuropoda melanoleuca	85.65	0.00e+00	1896.00
IUUC-Apl-003521	Anas platyrhynchos	73.84	0.00e+00	1288.00
IUUC-Aca-004995	Anolis carolinensis	73.87	0.00e+00	1568.00
IUUC-Ame-011481	Astyanax mexicanus	61.51	0.00e+00	1238.00
IUUC-Bta-012618	Bos taurus	85.54	0.00e+00	999.00
IUUC-Cja-019430	Callithrix jacchus	94.13	0.00e+00	1993.00
IUUC-Cfa-020687	Canis familiaris	85.41	0.00e+00	1843.00
IUUC-Cpo-021985	Cavia porcellus	86.80	0.00e+00	1086.00
IUUC-Csa-023534	Chlorocebus sabaeus	99.17	0.00e+00	1026.00
IUUC-Cho-024363	Choloepus hoffmanni	78.82	0.00e+00	731.00
IUUC-Dre-027538	Danio rerio	60.72	0.00e+00	1243.00
IUUC-Dno-029126	Dasypus novemcinctus	82.54	0.00e+00	1857.00
IUUC-Dor-030172	Dipodomys ordii	86.58	0.00e+00	1628.00
IUUC-Eca-033868	Equus caballus	84.66	0.00e+00	1830.00
IUUC-Eeu-034881	Erinaceus europaeus	69.07	0.00e+00	1360.00
IUUC-Fca-036203	Felis catus	81.32	0.00e+00	1706.00
IUUC-Fal-036668	Ficedula albicollis	74.39	0.00e+00	1675.00
IUUC-Gmo-039195	Gadus morhua	85.05	0.00e+00	779.00
IUUC-Gac-041789	Gasterosteus aculeatus	84.66	0.00e+00	875.00
IUUC-Ggo-044904	Gorilla gorilla	94.03	0.00e+00	1949.00
IUUC-Hsa-046254	Homo sapiens	99.45	0.00e+00	1968.00
IUUC-Itr-047948	Ictidomys tridecemlineatus	88.10	0.00e+00	1667.00
IUUC-Lch-050079	Latimeria chalumnae	66.52	0.00e+00	1459.00
IUUC-Loc-052265	Lepisosteus oculatus	83.50	0.00e+00	869.00
IUUC-Laf-053806	Loxodonta africana	83.87	0.00e+00	1845.00
IUUC-Mcc-055253	Macaca mulatta	96.15	0.00e+00	1957.00
IUUC-Meu-056509	Macropus eugenii	83.74	0.00e+00	814.00
IUUC-Mga-059600	Meleagris gallopavo	74.96	0.00e+00	1678.00
IUUC-Mmr-061586	Microcebus murinus	89.07	0.00e+00	1796.00
IUUC-Mdo-062126	Monodelphis domestica	75.46	0.00e+00	1635.00
IUUC-Mmu-063164	Mus musculus	81.34	0.00e+00	1652.00
IUUC-Mpu-065992	Mustela putorius furo	84.93	0.00e+00	1875.00
IUUC-Mlu-067728	Myotis lucifugus	78.06	0.00e+00	1607.00
IUUC-Nle-069546	Nomascus leucogenys	98.07	0.00e+00	1962.00
IUUC-Opr-070872	Ochotona princeps	84.63	0.00e+00	1759.00
IUUC-Ont-072296	Oreochromis niloticus	86.53	0.00e+00	911.00
IUUC-Ocu-074068	Oryctolagus cuniculus	84.59	0.00e+00	1766.00
IUUC-Ola-086756	Oryzias latipes	86.12	0.00e+00	907.00
IUUC-Oga-089066	Otolemur garnettii	89.56	0.00e+00	1930.00
IUUC-Oar-090416	Ovis aries	85.19	0.00e+00	995.00
IUUC-Pan-092438	Papio anubis	96.15	0.00e+00	1956.00
IUUC-Psi-093920	Pelodiscus sinensis	73.77	0.00e+00	1641.00
IUUC-Pfo-096334	Poecilia formosa	85.05	0.00e+00	890.00
IUUC-Pab-098452	Pongo abelii	97.09	0.00e+00	1998.00
IUUC-Pca-101081	Procavia capensis	79.31	0.00e+00	1738.00
IUUC-Rno-105102	Rattus norvegicus	81.88	0.00e+00	1652.00
IUUC-Sha-106917	Sarcophilus harrisii	74.93	0.00e+00	1640.00
IUUC-Sar-113711	Sorex araneus	79.37	0.00e+00	1519.00
IUUC-Tgu-116553	Taeniopygia guttata	77.95	0.00e+00	1702.00
IUUC-Tru-118069	Takifugu rubripes	85.31	0.00e+00	900.00
IUUC-Tni-120617	Tetraodon nigroviridis	81.92	0.00e+00	886.00
IUUC-Ttr-129256	Tursiops truncatus	79.12	0.00e+00	1029.00
IUUC-Xtr-132593	Xenopus tropicalis	71.18	0.00e+00	1528.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence