iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067131

Ensembl Protein ID

ENSMLUP00000010988.2

UniProt Accession

G1PJQ1; G1PJQ1_MYOLU

Genbank Protein ID

ENSMLUP00000010988

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02023906

Gene Name

MYLIP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000012057.2	ENSMLUT00000012061.2	ENSMLUP00000010988.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	95.51	0.00e+00	831.00	IUUC-Hsa-046869

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MLCYVTRPDV LMEVEVEAKA NGEDCPYQVC RRLGIIEVDY FGLQFTGSKG ESLWLNLRNR 60
ISQQMDGLAP YRLKLRVKFF VEPHLILQEQ TRHIFFLHIK EALLAGHLQC SSEQAVELSA 120

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Nucleotide Sequence
(Fasta)

ATGCTGTGCT ATGTGACGAG GCCGGACGCG GGTGCTGATG GAGGTGGAGG TGGAAGCGAA 60
AGCCAACGGC GAGGACTGCC CTTACCAAGG TGAGGATGAA GGGCCAAGAG GGGACCTCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR019749--Band_41_domain
IPR001370--BIR_rpt
IPR000798--Ez/rad/moesin-like
IPR014352--FERM/acyl-CoA-bd_prot_3-hlx
IPR019748--FERM_central
IPR000299--FERM_domain
IPR018979--FERM_N
IPR018980--FERM_PH-like_C
IPR011993--PH_dom-like
IPR029071--Ubiquitin-rel_dom
IPR001841--Znf_RING

PROSITE

PS50057--FERM_3
PS50089--ZF_RING_2

Pfam

PF09380--FERM_C
PF00373--FERM_M
PF09379--FERM_N

PRINTS

PR00935--BAND41
PR00661--ERMFAMILY

SMART

SM00295--B41
SM01196--FERM_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005856--C:cytoskeleton
GO:0019898--C:extrinsic component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042632--P:cholesterol homeostasis
GO:0010989--P:negative regulation of low-density lipoprotein particle clearance
GO:0007399--P:nervous system development
GO:0045732--P:positive regulation of protein catabolic process
GO:0031648--P:protein destabilization
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0032803--P:regulation of low-density lipoprotein particle receptor catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001425	Ailuropoda melanoleuca	95.67	0.00e+00	832.00
IUUC-Apl-003704	Anas platyrhynchos	90.45	0.00e+00	777.00
IUUC-Aca-004645	Anolis carolinensis	86.97	0.00e+00	788.00
IUUC-Ame-011401	Astyanax mexicanus	73.77	0.00e+00	646.00
IUUC-Bta-012752	Bos taurus	95.00	0.00e+00	714.00
IUUC-Cja-019734	Callithrix jacchus	94.83	0.00e+00	828.00
IUUC-Cfa-020145	Canis familiaris	95.26	0.00e+00	754.00
IUUC-Cpo-021436	Cavia porcellus	94.21	0.00e+00	723.00
IUUC-Csa-024248	Chlorocebus sabaeus	95.28	0.00e+00	830.00
IUUC-Cho-024528	Choloepus hoffmanni	83.56	0.00e+00	689.00
IUUC-Cin-025748	Ciona intestinalis	36.33	3.00e-45	175.00
IUUC-Csv-025837	Ciona savignyi	38.85	7.00e-89	321.00
IUUC-Dre-027847	Danio rerio	75.11	0.00e+00	661.00
IUUC-Dno-029860	Dasypus novemcinctus	95.53	0.00e+00	703.00
IUUC-Dor-030664	Dipodomys ordii	81.57	0.00e+00	691.00
IUUC-Dse-031509	Dothistroma septosporum	49.02	5.00e-11	63.20
IUUC-Dme-031990	Drosophila melanogaster	31.53	7.00e-38	152.00
IUUC-Ete-032496	Echinops telfairi	74.46	6.00e-150	523.00
IUUC-Eca-033674	Equus caballus	94.43	0.00e+00	874.00
IUUC-Eeu-035048	Erinaceus europaeus	87.19	0.00e+00	782.00
IUUC-Fca-036547	Felis catus	95.67	0.00e+00	830.00
IUUC-Fal-037504	Ficedula albicollis	90.65	0.00e+00	765.00
IUUC-Fox-037905	Fusarium oxysporum	29.49	2.00e-03	35.40
IUUC-Gmo-038660	Gadus morhua	73.75	1.00e-149	522.00
IUUC-Gga-040123	Gallus gallus	88.31	0.00e+00	803.00
IUUC-Gac-042073	Gasterosteus aculeatus	71.88	2.00e-179	621.00
IUUC-Ggo-045387	Gorilla gorilla	95.51	0.00e+00	833.00
IUUC-Hsa-046869	Homo sapiens	95.51	0.00e+00	835.00
IUUC-Itr-047917	Ictidomys tridecemlineatus	93.26	0.00e+00	819.00
IUUC-Lch-049990	Latimeria chalumnae	82.47	0.00e+00	775.00
IUUC-Loc-051908	Lepisosteus oculatus	76.12	0.00e+00	678.00
IUUC-Lma-053223	Leptosphaeria maculans	52.50	8.00e-08	53.50
IUUC-Laf-053915	Loxodonta africana	93.26	0.00e+00	811.00
IUUC-Mcc-054865	Macaca mulatta	95.06	0.00e+00	829.00
IUUC-Meu-056826	Macropus eugenii	85.71	3.00e-72	265.00
IUUC-Mga-059827	Meleagris gallopavo	89.95	0.00e+00	731.00
IUUC-Mmr-060734	Microcebus murinus	94.83	0.00e+00	846.00
IUUC-Mdo-062988	Monodelphis domestica	93.26	0.00e+00	866.00
IUUC-Mmu-064415	Mus musculus	94.38	0.00e+00	787.00
IUUC-Mpu-066118	Mustela putorius furo	96.32	0.00e+00	726.00
IUUC-Nle-070112	Nomascus leucogenys	95.51	0.00e+00	832.00
IUUC-Opr-071193	Ochotona princeps	91.55	0.00e+00	776.00
IUUC-Ont-072635	Oreochromis niloticus	73.33	0.00e+00	635.00
IUUC-Oan-073266	Ornithorhynchus anatinus	91.11	0.00e+00	770.00
IUUC-Ocu-074903	Oryctolagus cuniculus	91.91	0.00e+00	824.00
IUUC-Ola-087533	Oryzias latipes	70.78	3.00e-175	607.00
IUUC-Oga-087979	Otolemur garnettii	94.83	0.00e+00	853.00
IUUC-Oar-089747	Ovis aries	94.95	0.00e+00	786.00
IUUC-Ptr-090732	Pan troglodytes	95.73	0.00e+00	834.00
IUUC-Pan-092032	Papio anubis	95.28	0.00e+00	830.00
IUUC-Psi-093296	Pelodiscus sinensis	91.13	0.00e+00	803.00
IUUC-Pma-094351	Petromyzon marinus	51.98	4.00e-33	134.00
IUUC-Pfo-097183	Poecilia formosa	73.02	2.00e-172	598.00
IUUC-Pab-098177	Pongo abelii	95.28	0.00e+00	832.00
IUUC-Pca-100734	Procavia capensis	92.36	0.00e+00	816.00
IUUC-Pva-102778	Pteropus vampyrus	96.63	0.00e+00	834.00
IUUC-Rno-106039	Rattus norvegicus	93.93	0.00e+00	816.00
IUUC-Sha-106869	Sarcophilus harrisii	93.51	0.00e+00	817.00
IUUC-Sar-113587	Sorex araneus	64.90	9.00e-151	526.00
IUUC-Ssc-116212	Sus scrofa	96.18	0.00e+00	832.00
IUUC-Tgu-116871	Taeniopygia guttata	90.41	0.00e+00	763.00
IUUC-Tru-117925	Takifugu rubripes	72.99	0.00e+00	665.00
IUUC-Tsy-118815	Tarsius syrichta	94.23	0.00e+00	782.00
IUUC-Tni-120007	Tetraodon nigroviridis	72.97	0.00e+00	633.00
IUUC-Tbe-127381	Tupaia belangeri	91.48	0.00e+00	667.00
IUUC-Ttr-129025	Tursiops truncatus	81.49	0.00e+00	654.00
IUUC-Vpa-130164	Vicugna pacos	69.59	3.00e-159	554.00
IUUC-Xtr-132800	Xenopus tropicalis	83.60	0.00e+00	742.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence