iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062691

Ensembl Protein ID

ENSMODP00000012751.2

UniProt Accession

F6SU50; F6SU50_MONDO

Protein Name

Uncharacterized protein

Gene Name

CRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000010187.3	ENSMODT00000012986.2	ENSMODP00000012751.2
ENSMODG00000010187.3	ENSMODT00000030299.2	ENSMODP00000028717.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.90e-18	64.7	137	192

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +e+v++l+d++++++++L +kkGd++++   ++ +e W+++ ++ egkrG++P  +vek
   Q: 137  EEYVRALFDFNGNDEEDLPFKKGDILKI--RDKPEEQWWNA-EDSEGKRGMIPVPYVEK 192
           689*************************..6999******9.5**************98 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAGNFDSEER SSWYWGRLSR QEAVALLQGQ RHGVFLVRDS STSPGDYVLS VSENSRSAKG 60
PLMVTQRGPL LPSPPESVIL QNLLGLNPSR LRIGDQEFDS LPALLEFYKI HYLDTTTLIE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGGAATCAG CTGCAGTCTC GGCCTAGGCC AGGCGGTGAC GCACGAGAGC CTGCCGGCAA 60
GGGTTGCAAT GCGCACGCTC GTGCTTGCCC TTCTCCCAAT GGCGGCCGTT CGTCTCCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0048013--P:ephrin receptor signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001192	Ailuropoda melanoleuca	87.79	2.00e-147	514.00
IUUC-Apl-003225	Anas platyrhynchos	92.51	1.00e-121	428.00
IUUC-Aca-004818	Anolis carolinensis	70.08	6.00e-89	319.00
IUUC-Ame-011721	Astyanax mexicanus	66.15	4.00e-114	404.00
IUUC-Bta-012320	Bos taurus	88.31	1.00e-150	525.00
IUUC-Cel-018307	Caenorhabditis elegans	30.33	4.00e-26	111.00
IUUC-Cja-019935	Callithrix jacchus	88.06	3.00e-155	540.00
IUUC-Cfa-021221	Canis familiaris	88.31	3.00e-150	524.00
IUUC-Cpo-021592	Cavia porcellus	82.03	1.00e-133	468.00
IUUC-Csa-024128	Chlorocebus sabaeus	84.06	3.00e-90	323.00
IUUC-Cho-024775	Choloepus hoffmanni	86.69	3.00e-150	524.00
IUUC-Dre-027390	Danio rerio	66.06	3.00e-115	407.00
IUUC-Dno-029847	Dasypus novemcinctus	88.31	1.00e-150	525.00
IUUC-Dor-030360	Dipodomys ordii	86.36	2.00e-150	525.00
IUUC-Ete-032604	Echinops telfairi	93.72	2.00e-121	427.00
IUUC-Eca-033233	Equus caballus	87.99	2.00e-150	524.00
IUUC-Eeu-034642	Erinaceus europaeus	93.72	6.00e-121	426.00
IUUC-Fca-035955	Felis catus	95.09	7.00e-124	436.00
IUUC-Fal-037152	Ficedula albicollis	81.38	1.00e-134	472.00
IUUC-Gmo-038849	Gadus morhua	64.89	4.00e-113	400.00
IUUC-Gga-040861	Gallus gallus	80.84	5.00e-144	503.00
IUUC-Gac-041627	Gasterosteus aculeatus	64.42	7.00e-114	403.00
IUUC-Ggo-045475	Gorilla gorilla	88.31	1.00e-150	525.00
IUUC-Hsa-046008	Homo sapiens	88.31	1.00e-150	525.00
IUUC-Itr-048906	Ictidomys tridecemlineatus	86.42	9.00e-122	429.00
IUUC-Lch-050509	Latimeria chalumnae	80.06	5.00e-143	500.00
IUUC-Loc-052229	Lepisosteus oculatus	68.12	6.00e-100	356.00
IUUC-Laf-053896	Loxodonta africana	88.35	2.00e-154	538.00
IUUC-Mcc-055280	Macaca mulatta	88.31	1.00e-150	525.00
IUUC-Meu-056783	Macropus eugenii	98.65	1.00e-128	451.00
IUUC-Mga-059345	Meleagris gallopavo	92.83	5.00e-122	429.00
IUUC-Mmu-063691	Mus musculus	88.31	1.00e-150	525.00
IUUC-Mpu-065737	Mustela putorius furo	87.99	1.00e-150	525.00
IUUC-Mlu-067005	Myotis lucifugus	86.04	6.00e-147	513.00
IUUC-Nle-070154	Nomascus leucogenys	95.09	1.00e-123	434.00
IUUC-Opr-071114	Ochotona princeps	88.85	3.00e-157	547.00
IUUC-Ont-071696	Oreochromis niloticus	65.41	3.00e-108	384.00
IUUC-Oan-072967	Ornithorhynchus anatinus	85.61	2.00e-125	441.00
IUUC-Ola-087265	Oryzias latipes	63.79	3.00e-90	324.00
IUUC-Oga-088266	Otolemur garnettii	87.01	9.00e-150	522.00
IUUC-Oar-089221	Ovis aries	87.01	2.00e-147	514.00
IUUC-Ptr-091463	Pan troglodytes	84.09	8.00e-139	486.00
IUUC-Pan-092242	Papio anubis	88.31	1.00e-150	525.00
IUUC-Psi-093287	Pelodiscus sinensis	93.75	9.00e-124	435.00
IUUC-Pfo-097378	Poecilia formosa	64.71	1.00e-108	385.00
IUUC-Pab-097823	Pongo abelii	84.06	3.00e-90	323.00
IUUC-Pca-101068	Procavia capensis	88.31	1.00e-150	525.00
IUUC-Ptt-103815	Puccinia triticina	42.86	5.00e-10	58.20
IUUC-Rno-105288	Rattus norvegicus	87.99	4.00e-150	523.00
IUUC-Sar-113453	Sorex araneus	82.47	4.00e-142	497.00
IUUC-Tgu-116926	Taeniopygia guttata	80.84	4.00e-142	496.00
IUUC-Tru-117806	Takifugu rubripes	64.97	3.00e-112	398.00
IUUC-Tni-120497	Tetraodon nigroviridis	65.33	4.00e-109	387.00
IUUC-Tbe-127436	Tupaia belangeri	84.09	5.00e-133	466.00
IUUC-Ttr-129109	Tursiops truncatus	95.52	1.00e-123	435.00
IUUC-Vpa-130527	Vicugna pacos	87.99	1.00e-148	518.00
IUUC-Xtr-131808	Xenopus tropicalis	80.45	1.00e-144	505.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence