iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091046

Ensembl Protein ID

ENSPTRP00000016161.5

UniProt Accession

H2QDN0; H2QDN0_PANTR

Genbank Protein ID

JAA28301.1

Protein Name

Mitogen-activated protein kinase kinase kinase 3

Genbank Nucleotide ID

AACZ03108595

Gene Name

MAP3K3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000009518.5	ENSPTRT00000017452.5	ENSPTRP00000016161.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/PB1	1.70e-16	60.2	75	150

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/PB1

   S: 1    tvrvkvsykgeirsfaldlekpgkfedLlkavrtltelknsevalkYeDedGDlvtlksDedldkavslla...skksllrll 80
           +vr+k++++ge r+  +++++p+k+ed++++v+t   ++++ ++l+Y++++ +++ lk+++dldka+++l+   s+ksl r+l
   Q: 75   DVRIKFEHNGERRI--IAFSRPVKYEDVEHKVTT---VFGQPLDLHYMNNELSIL-LKNQDDLDKAIDILDrssSMKSL-RIL 150
           59**********77..******************...******************.***************77444444.444 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MDEQEALNSI MNDLVALQMN RHHRMPGYET MKNKDTGHSN RQKKHNSSSS ALLNSPTVTT 60
SSCAGASEKK KFLSDVRIKF EHNGERRIIA FSRPVKYEDV EHKVTTVFGQ PLDLHYMNNE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGAACGGTG GCCGGACGGA GAGACTGCGG GTCTGAGGGA CTGGCGGGCG GGCGGGCCGA 60
GCGGCGCCGC CGAGGCCGGG CTGGGCCGAG CCCAGGAGCG CCCGGGATGT AGCGGGCCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR011009--Kinase-like_dom
IPR000270--PB1_dom
IPR000719--Prot_kinase_dom

PROSITE

PS51745--PB1
PS50011--PROTEIN_KINASE_DOM

Pfam

PF00564--PB1
PF00069--Pkinase

SMART

SM00666--PB1
SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004702--F:signal transducer, downstream of receptor, with serine/threonine kinase activity
GO:0030036--P:actin cytoskeleton organization
GO:0001568--P:blood vessel development
GO:0035556--P:intracellular signal transduction
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1900745--P:positive regulation of p38MAPK cascade
GO:0046777--P:protein autophosphorylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001464	Ailuropoda melanoleuca	97.71	0.00e+00	1299.00
IUUC-Ame-011807	Astyanax mexicanus	73.97	0.00e+00	949.00
IUUC-Bta-012717	Bos taurus	92.38	0.00e+00	1248.00
IUUC-Cja-019548	Callithrix jacchus	98.97	0.00e+00	1159.00
IUUC-Cfa-020785	Canis familiaris	92.85	0.00e+00	1259.00
IUUC-Cpo-021444	Cavia porcellus	92.23	0.00e+00	1245.00
IUUC-Csa-023898	Chlorocebus sabaeus	99.85	0.00e+00	1368.00
IUUC-Cin-025443	Ciona intestinalis	46.44	8.00e-134	470.00
IUUC-Dre-027587	Danio rerio	74.12	0.00e+00	980.00
IUUC-Dno-028984	Dasypus novemcinctus	95.43	0.00e+00	1286.00
IUUC-Eca-034089	Equus caballus	92.99	0.00e+00	1259.00
IUUC-Fca-035656	Felis catus	92.89	0.00e+00	1243.00
IUUC-Ggo-045339	Gorilla gorilla	99.85	0.00e+00	1368.00
IUUC-Hsa-046137	Homo sapiens	95.13	0.00e+00	1291.00
IUUC-Itr-048091	Ictidomys tridecemlineatus	92.84	0.00e+00	1257.00
IUUC-Lpe-050706	Leersia perrieri	46.44	1.00e-68	254.00
IUUC-Loc-052751	Lepisosteus oculatus	76.16	0.00e+00	1037.00
IUUC-Laf-054342	Loxodonta africana	92.10	0.00e+00	1244.00
IUUC-Mcc-055631	Macaca mulatta	99.70	0.00e+00	1364.00
IUUC-Mga-059565	Meleagris gallopavo	81.89	0.00e+00	1091.00
IUUC-Mmr-060745	Microcebus murinus	97.56	0.00e+00	1313.00
IUUC-Mmu-063432	Mus musculus	91.93	0.00e+00	1246.00
IUUC-Mpu-066544	Mustela putorius furo	96.75	0.00e+00	1290.00
IUUC-Mlu-067655	Myotis lucifugus	91.93	0.00e+00	1245.00
IUUC-Nle-070048	Nomascus leucogenys	93.29	0.00e+00	1221.00
IUUC-Ont-071889	Oreochromis niloticus	73.36	0.00e+00	975.00
IUUC-Oan-073137	Ornithorhynchus anatinus	73.31	0.00e+00	699.00
IUUC-Ola-087055	Oryzias latipes	69.20	0.00e+00	910.00
IUUC-Oga-088913	Otolemur garnettii	88.01	0.00e+00	1177.00
IUUC-Oar-090321	Ovis aries	96.95	0.00e+00	1306.00
IUUC-Pan-092280	Papio anubis	99.54	0.00e+00	1340.00
IUUC-Pfo-096365	Poecilia formosa	73.44	0.00e+00	978.00
IUUC-Pab-097785	Pongo abelii	99.85	0.00e+00	1368.00
IUUC-Pva-102740	Pteropus vampyrus	97.25	0.00e+00	1305.00
IUUC-Rno-104946	Rattus norvegicus	91.63	0.00e+00	1242.00
IUUC-Ssc-115554	Sus scrofa	91.96	0.00e+00	1225.00
IUUC-Tgu-117312	Taeniopygia guttata	85.37	0.00e+00	1164.00
IUUC-Tni-120426	Tetraodon nigroviridis	72.10	0.00e+00	950.00
IUUC-Ttr-128646	Tursiops truncatus	97.72	0.00e+00	1317.00
IUUC-Vpa-130197	Vicugna pacos	95.40	0.00e+00	814.00
IUUC-Xtr-132121	Xenopus tropicalis	79.76	0.00e+00	1066.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence