iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gga-040505

Ensembl Protein ID

ENSGALP00000011884.1

UniProt Accession

F1NBN7; F1NBN7_CHICK

Genbank Protein ID

ENSGALP00000011884

Protein Name

B-cell lymphoma 6 protein homolog

Genbank Nucleotide ID

AADN04000078

Gene Name

BCL6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000007357.2	ENSGALT00000011898.1	ENSGALP00000011884.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.80e-14	54.2	32	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.dvqpevfrallkFlYtgklden 68
           +Dv+++v++e+f+ahk vL+a+S  Fy+ f+ +l+ +   + ++++ ++ pe f  ll+F+Yt++l++ 
   Q: 32   TDVVIIVNREQFRAHKTVLMACSGLFYSIFTDQLKCN--LNVINLDpEINPEGFCILLDFMYTSRLNLR 98
           7**********************************76..69*****88*****************9875 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MASPADSCIQ FTRHASDVLL NLNRLRSRDI LTDVVIIVNR EQFRAHKTVL MACSGLFYSI 60
FTDQLKCNLN VINLDPEINP EGFCILLDFM YTSRLNLREN NIMAVMATAL YLQMEHVVDT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAGAACTGG GGTTCTTAGA AGTGGTGATG CAAGGAGTTT CTAGGAAAGC CCGGAGACCA 60
GGTGATTGCT GCTTCTATTG CCGCGGCCGA TTTTACCCTT TAATTCTCTC TCTCTCTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0005654--C:nucleoplasm
GO:0005657--C:replication fork
GO:0031490--F:chromatin DNA binding
GO:0001161--F:intronic transcription regulatory region sequence-specific DNA binding
GO:0046872--F:metal ion binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227--F:transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0030036--P:actin cytoskeleton organization
GO:0030183--P:B cell differentiation
GO:0000902--P:cell morphogenesis
GO:0006974--P:cellular response to DNA damage stimulus
GO:0048821--P:erythrocyte development
GO:0002467--P:germinal center formation
GO:0043066--P:negative regulation of apoptotic process
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0001953--P:negative regulation of cell-matrix adhesion
GO:2000773--P:negative regulation of cellular senescence
GO:0048294--P:negative regulation of isotype switching to IgE isotypes
GO:0032764--P:negative regulation of mast cell cytokine production
GO:0045746--P:negative regulation of Notch signaling pathway
GO:0035024--P:negative regulation of Rho protein signal transduction
GO:0045629--P:negative regulation of T-helper 2 cell differentiation
GO:0043065--P:positive regulation of apoptotic process
GO:0030890--P:positive regulation of B cell proliferation
GO:0051272--P:positive regulation of cellular component movement
GO:0031065--P:positive regulation of histone deacetylation
GO:0045666--P:positive regulation of neuron differentiation
GO:0000060--P:protein import into nucleus, translocation
GO:0043087--P:regulation of GTPase activity
GO:0050727--P:regulation of inflammatory response
GO:0043380--P:regulation of memory T cell differentiation
GO:0007266--P:Rho protein signal transduction
GO:0007283--P:spermatogenesis
GO:0042092--P:type 2 immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001625	Ailuropoda melanoleuca	78.40	0.00e+00	1134.00
IUUC-Apl-003263	Anas platyrhynchos	96.90	0.00e+00	1396.00
IUUC-Ame-010714	Astyanax mexicanus	59.23	0.00e+00	816.00
IUUC-Bta-012576	Bos taurus	78.20	0.00e+00	1123.00
IUUC-Cja-018906	Callithrix jacchus	79.32	0.00e+00	1162.00
IUUC-Cfa-021058	Canis familiaris	77.12	0.00e+00	1115.00
IUUC-Cpo-022328	Cavia porcellus	79.18	0.00e+00	1165.00
IUUC-Csa-023942	Chlorocebus sabaeus	78.12	0.00e+00	1139.00
IUUC-Cho-024599	Choloepus hoffmanni	79.53	0.00e+00	690.00
IUUC-Cin-025470	Ciona intestinalis	80.99	4.00e-60	226.00
IUUC-Csv-025860	Ciona savignyi	82.11	4.00e-60	226.00
IUUC-Dre-027605	Danio rerio	60.30	0.00e+00	834.00
IUUC-Dno-029476	Dasypus novemcinctus	73.98	0.00e+00	1088.00
IUUC-Dor-030724	Dipodomys ordii	78.34	0.00e+00	1137.00
IUUC-Ete-032678	Echinops telfairi	77.22	0.00e+00	1100.00
IUUC-Eca-034377	Equus caballus	78.76	0.00e+00	1149.00
IUUC-Eeu-034532	Erinaceus europaeus	72.27	0.00e+00	668.00
IUUC-Fca-036465	Felis catus	78.20	0.00e+00	1143.00
IUUC-Fal-036977	Ficedula albicollis	95.08	0.00e+00	1408.00
IUUC-Gmo-039515	Gadus morhua	62.46	2.00e-114	405.00
IUUC-Gac-041393	Gasterosteus aculeatus	59.36	0.00e+00	809.00
IUUC-Gma-042854	Glycine max	28.87	2.00e-04	41.20
IUUC-Ggo-044500	Gorilla gorilla	78.40	0.00e+00	1146.00
IUUC-Hsa-046648	Homo sapiens	78.90	0.00e+00	1153.00
IUUC-Itr-048732	Ictidomys tridecemlineatus	75.42	0.00e+00	1087.00
IUUC-Lch-050387	Latimeria chalumnae	58.44	0.00e+00	768.00
IUUC-Loc-052103	Lepisosteus oculatus	62.87	0.00e+00	872.00
IUUC-Laf-053636	Loxodonta africana	77.70	0.00e+00	1145.00
IUUC-Mcc-055290	Macaca mulatta	78.48	0.00e+00	1144.00
IUUC-Meu-055910	Macropus eugenii	76.09	0.00e+00	1112.00
IUUC-Mga-059925	Meleagris gallopavo	98.87	0.00e+00	1412.00
IUUC-Mvi-060431	Microbotryum violaceum	31.33	8.00e-04	38.10
IUUC-Mmr-060855	Microcebus murinus	79.47	0.00e+00	1150.00
IUUC-Mdo-062982	Monodelphis domestica	73.96	5.00e-82	298.00
IUUC-Mmu-063292	Mus musculus	78.65	0.00e+00	1124.00
IUUC-Mpu-066598	Mustela putorius furo	78.06	0.00e+00	1114.00
IUUC-Mlu-067370	Myotis lucifugus	78.82	0.00e+00	1125.00
IUUC-Nle-069870	Nomascus leucogenys	78.34	0.00e+00	1145.00
IUUC-Opr-070986	Ochotona princeps	77.72	0.00e+00	1115.00
IUUC-Ont-072475	Oreochromis niloticus	60.20	0.00e+00	775.00
IUUC-Oan-073596	Ornithorhynchus anatinus	81.46	0.00e+00	1174.00
IUUC-Ocu-073970	Oryctolagus cuniculus	78.82	0.00e+00	1163.00
IUUC-Ola-087102	Oryzias latipes	59.17	0.00e+00	802.00
IUUC-Oga-088873	Otolemur garnettii	78.79	0.00e+00	1156.00
IUUC-Oar-090083	Ovis aries	73.42	0.00e+00	1027.00
IUUC-Ptr-090628	Pan troglodytes	78.76	0.00e+00	1151.00
IUUC-Pan-092324	Papio anubis	77.98	0.00e+00	1134.00
IUUC-Psi-093695	Pelodiscus sinensis	87.45	0.00e+00	1248.00
IUUC-Pfo-096460	Poecilia formosa	59.10	0.00e+00	811.00
IUUC-Pab-098012	Pongo abelii	78.62	0.00e+00	1149.00
IUUC-Pca-100127	Procavia capensis	77.11	0.00e+00	1055.00
IUUC-Pva-102830	Pteropus vampyrus	78.34	0.00e+00	1127.00
IUUC-Rno-105752	Rattus norvegicus	78.93	0.00e+00	1125.00
IUUC-Sha-107259	Sarcophilus harrisii	79.24	0.00e+00	1162.00
IUUC-Sar-113610	Sorex araneus	75.65	0.00e+00	879.00
IUUC-Ssc-115327	Sus scrofa	78.76	0.00e+00	1145.00
IUUC-Tgu-116457	Taeniopygia guttata	96.33	0.00e+00	1424.00
IUUC-Tru-118520	Takifugu rubripes	58.47	0.00e+00	787.00
IUUC-Tsy-119245	Tarsius syrichta	43.21	5.00e-48	184.00
IUUC-Tni-119969	Tetraodon nigroviridis	58.75	0.00e+00	789.00
IUUC-Tbe-127327	Tupaia belangeri	71.87	0.00e+00	1024.00
IUUC-Ttr-129204	Tursiops truncatus	78.14	0.00e+00	1122.00
IUUC-Vpa-130647	Vicugna pacos	86.24	4.00e-56	211.00
IUUC-Xtr-132937	Xenopus tropicalis	68.46	0.00e+00	941.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence