iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036055

Ensembl Protein ID

ENSFCAP00000025370.1

UniProt Accession

M3XFF9; M3XFF9_FELCA

Genbank Protein ID

ENSFCAP00000025370

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02150450

Gene Name

RNF144B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000028127.1	ENSFCAT00000030758.1	ENSFCAP00000025370.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	1.10e-51	176.2	30	222

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+e+s +++t+l+eC++ fC++Clkqyl+l+i+eg+ + iscp++ c  +  l+e+ei++ lv  ++++ y++l++e++v+ d+++
   Q: 30   CKLCLCEQSLDKMTTLQECQCLFCTDCLKQYLQLAIREGCGSPISCPDTVCLGRgiLQEAEIAC-LVPVDQFQLYQRLKFEREVHLDPHR 118
           ***************************************************998889*******.6999********************* PP
   S: 89   kwcpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
           +wcp +dC++v+ +++++  + + vec++c+ +fC++Ck++wH+++sC++ +  +  te   + a   + +ea +k+Cp C+vyie+neg
   Q: 119  TWCPVADCQTVCPVASSDpgQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPVVLPTE---HGALFGTDTEAPIKQCPVCRVYIERNEG 205
           *************9998877899999*****************************9999...89************************** PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m+C++Ck++fCw+C
   Q: 206  CAQMMCKNCKHTFCWYC 222
           ***************** PP

Organism

Felis catus

Protein Sequence
(Fasta)

MGSAGRFHCL TMTTENPTPG DLAPSPLVTC KLCLCEQSLD KMTTLQECQC LFCTDCLKQY 60
LQLAIREGCG SPISCPDTVC LGRGILQEAE IACLVPVDQF QLYQRLKFER EVHLDPHRTW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCCAAGAT CTGAACACTG CATTGGCAGA TTCAAAAGTC TATGTTCTTT TCATAGCATG 60
ATACTGACTT ACTTTATGGT AATGTGGTTT ACTCAAGGTG TTTCTGATTT TAAATAACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

fca:101099205

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001257	Ailuropoda melanoleuca	93.73	2.00e-168	584.00
IUUC-Atr-002709	Amborella trichopoda	28.64	4.00e-18	86.70
IUUC-Apl-004112	Anas platyrhynchos	80.07	3.00e-127	447.00
IUUC-Aca-004533	Anolis carolinensis	76.57	3.00e-136	477.00
IUUC-Bta-012641	Bos taurus	92.11	1.00e-165	575.00
IUUC-Cja-019626	Callithrix jacchus	77.23	1.00e-135	475.00
IUUC-Cfa-020702	Canis familiaris	93.40	7.00e-169	585.00
IUUC-Cpo-022147	Cavia porcellus	93.40	5.00e-168	583.00
IUUC-Csa-023473	Chlorocebus sabaeus	92.74	3.00e-168	583.00
IUUC-Cho-024298	Choloepus hoffmanni	88.72	1.00e-136	478.00
IUUC-Dre-028099	Danio rerio	64.31	7.00e-91	327.00
IUUC-Dno-029122	Dasypus novemcinctus	86.18	2.00e-152	531.00
IUUC-Dor-030669	Dipodomys ordii	93.99	1.00e-130	458.00
IUUC-Ete-033141	Echinops telfairi	78.88	3.00e-127	447.00
IUUC-Eca-034360	Equus caballus	93.07	6.00e-168	582.00
IUUC-Eeu-034538	Erinaceus europaeus	74.18	4.00e-86	310.00
IUUC-Fal-037339	Ficedula albicollis	78.49	3.00e-129	454.00
IUUC-Gmo-038780	Gadus morhua	60.44	1.00e-84	306.00
IUUC-Gga-040256	Gallus gallus	77.94	2.00e-129	454.00
IUUC-Gac-042127	Gasterosteus aculeatus	62.86	7.00e-92	330.00
IUUC-Ggo-044867	Gorilla gorilla	94.06	3.00e-170	590.00
IUUC-Hsa-046928	Homo sapiens	93.73	1.00e-169	588.00
IUUC-Hvu-047484	Hordeum vulgare	30.20	8.00e-17	81.30
IUUC-Itr-048250	Ictidomys tridecemlineatus	96.89	7.00e-110	389.00
IUUC-Lch-050168	Latimeria chalumnae	74.10	1.00e-131	462.00
IUUC-Lpe-051649	Leersia perrieri	28.08	2.00e-15	77.80
IUUC-Loc-052150	Lepisosteus oculatus	59.85	2.00e-85	308.00
IUUC-Laf-053967	Loxodonta africana	91.09	2.00e-163	568.00
IUUC-Mcc-055898	Macaca mulatta	92.74	3.00e-168	583.00
IUUC-Meu-056628	Macropus eugenii	96.15	6.00e-43	167.00
IUUC-Mtr-057989	Medicago truncatula	26.76	5.00e-20	91.30
IUUC-Mga-059820	Meleagris gallopavo	76.87	1.00e-127	448.00
IUUC-Mmr-060680	Microcebus murinus	90.76	2.00e-164	570.00
IUUC-Mdo-062839	Monodelphis domestica	84.21	5.00e-150	523.00
IUUC-Mmu-063339	Mus musculus	85.15	2.00e-144	504.00
IUUC-Mac-065414	Musa acuminata	28.91	8.00e-20	90.90
IUUC-Mpu-065973	Mustela putorius furo	92.74	4.00e-167	580.00
IUUC-Mlu-067112	Myotis lucifugus	91.75	2.00e-157	548.00
IUUC-Nle-069795	Nomascus leucogenys	93.40	4.00e-170	590.00
IUUC-Opr-070390	Ochotona princeps	85.48	4.00e-148	516.00
IUUC-Ont-072329	Oreochromis niloticus	61.34	6.00e-88	317.00
IUUC-Oan-072980	Ornithorhynchus anatinus	82.97	2.00e-134	471.00
IUUC-Ocu-073845	Oryctolagus cuniculus	91.75	6.00e-167	579.00
IUUC-Ola-086872	Oryzias latipes	61.05	8.00e-84	303.00
IUUC-Oga-088954	Otolemur garnettii	90.76	2.00e-163	567.00
IUUC-Oar-089879	Ovis aries	92.11	1.00e-165	575.00
IUUC-Ptr-090685	Pan troglodytes	93.73	1.00e-169	588.00
IUUC-Pan-092086	Papio anubis	92.41	3.00e-168	583.00
IUUC-Psi-093481	Pelodiscus sinensis	79.54	5.00e-135	473.00
IUUC-Pfo-096065	Poecilia formosa	60.62	8.00e-91	326.00
IUUC-Pab-098031	Pongo abelii	93.40	8.00e-169	585.00
IUUC-Pop-099816	Populus trichocarpa	27.09	4.00e-15	75.90
IUUC-Pca-100936	Procavia capensis	89.44	3.00e-160	556.00
IUUC-Pva-102864	Pteropus vampyrus	82.84	2.00e-145	508.00
IUUC-Rno-105503	Rattus norvegicus	85.15	4.00e-144	503.00
IUUC-Sha-107425	Sarcophilus harrisii	84.87	7.00e-152	529.00
IUUC-Stu-112736	Solanum tuberosum	29.25	2.00e-20	92.40
IUUC-Ssc-115458	Sus scrofa	90.55	1.00e-152	531.00
IUUC-Tgu-117226	Taeniopygia guttata	77.42	5.00e-129	453.00
IUUC-Tru-118362	Takifugu rubripes	63.53	2.00e-91	328.00
IUUC-Tsy-119255	Tarsius syrichta	93.73	2.00e-169	587.00
IUUC-Tni-120140	Tetraodon nigroviridis	62.31	9.00e-87	312.00
IUUC-Tca-121059	Theobroma cacao	29.27	5.00e-16	77.80
IUUC-Tae-124420	Triticum aestivum	31.31	8.00e-17	82.00
IUUC-Tbe-127306	Tupaia belangeri	91.42	6.00e-165	572.00
IUUC-Ttr-128923	Tursiops truncatus	91.78	7.00e-154	536.00
IUUC-Vpa-130148	Vicugna pacos	91.42	4.00e-165	573.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence