iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000003015.3	ENSFCAT00000003015.3	ENSFCAP00000002776.3
ENSFCAG00000003015.3	ENSFCAT00000024059.1	ENSFCAP00000019510.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.60e-07	30.6	206	256

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..........kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C + +          ++ ++ l+C+H+fh+ C+  w    +   k+++CP+C+
   Q: 206  CAVCGQKIivelneegliEN-TYQLSCNHIFHEFCIRGW----CIVGKKQTCPYCK 256
           9***9988888887777555.999***************....889999******7 PP

Organism

Felis catus

Protein Sequence
(Fasta)

QISHTKLSAD DEWNLQQERM YKMHRGHESM HVEMILIFLC ALVIAQIVLV QWRQRHGRSY 60
NLVTLLQMWV VPLYFTIKLY WWRFLSMWGM FSVITSYVLF RATRKPLSGR TPRLVYKWFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGATCTCTC ACACAAAGCT TTCTGCGGAT GATGAATGGA AGTAAGTGAT TAGAATTTTT 60
TTAATTGTTT AAACTTACAT TTTAACTAAA AATTACATTT CCACCTTAAG AGTTTGAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001696	Ailuropoda melanoleuca	95.45	4.00e-177	613.00
IUUC-Ani-009461	Aspergillus nidulans	29.21	1.00e-03	38.50
IUUC-Bta-012417	Bos taurus	95.44	3.00e-179	620.00
IUUC-Cja-018928	Callithrix jacchus	94.50	6.00e-175	606.00
IUUC-Csa-024195	Chlorocebus sabaeus	96.48	7.00e-150	522.00
IUUC-Dre-028154	Danio rerio	79.14	6.00e-151	526.00
IUUC-Dno-030042	Dasypus novemcinctus	96.44	2.00e-171	594.00
IUUC-Ete-032805	Echinops telfairi	79.80	1.00e-135	475.00
IUUC-Eeu-035318	Erinaceus europaeus	83.44	7.00e-145	506.00
IUUC-Gac-042092	Gasterosteus aculeatus	76.00	2.00e-146	511.00
IUUC-Ggo-044923	Gorilla gorilla	95.78	2.00e-178	617.00
IUUC-Hsa-046067	Homo sapiens	96.09	1.00e-173	601.00
IUUC-Itr-049039	Ictidomys tridecemlineatus	95.77	2.00e-180	624.00
IUUC-Loc-052668	Lepisosteus oculatus	78.69	2.00e-151	528.00
IUUC-Mcc-055430	Macaca mulatta	97.07	0.00e+00	629.00
IUUC-Mmr-060873	Microcebus murinus	92.69	6.00e-167	579.00
IUUC-Mpu-066792	Mustela putorius furo	96.43	1.00e-178	618.00
IUUC-Mlu-066938	Myotis lucifugus	91.03	9.00e-173	598.00
IUUC-Nle-069138	Nomascus leucogenys	96.42	0.00e+00	625.00
IUUC-Opr-070342	Ochotona princeps	90.88	8.00e-171	592.00
IUUC-Ont-072601	Oreochromis niloticus	78.15	5.00e-150	523.00
IUUC-Ocu-074696	Oryctolagus cuniculus	94.14	2.00e-177	614.00
IUUC-Ola-086347	Oryzias latipes	78.15	1.00e-149	521.00
IUUC-Oga-089139	Otolemur garnettii	96.74	8.00e-180	622.00
IUUC-Ptr-091158	Pan troglodytes	96.74	0.00e+00	625.00
IUUC-Pfo-096037	Poecilia formosa	79.47	4.00e-144	503.00
IUUC-Pab-097624	Pongo abelii	95.78	3.00e-179	620.00
IUUC-Sar-113082	Sorex araneus	90.91	1.00e-136	478.00
IUUC-Tsy-118809	Tarsius syrichta	92.52	3.00e-163	566.00
IUUC-Tbe-127912	Tupaia belangeri	74.84	3.00e-132	464.00
IUUC-Vpa-130356	Vicugna pacos	93.18	6.00e-169	586.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence