iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-070084

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01184083

Gene Name

USP21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000014052.1	ENSNLET00000017940.1	ENSNLEP00000017080.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.50e-88	296.0	212	556

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy 87
           +Gl+NlgNtC++N+vLQcLs++++lr+++l+  ++++++     ++ +el++++++++ +lw  ++ +av+p+++ ++++k+ ++fsgy
   Q: 212  VGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRrDFRQEVPG---GGRAQELTEAFADVIGALWhPDSCEAVNPTRFRAVFQKYVPSFSGY 297
           6******************************667777776...5789***************888899********************* PP
   S: 88   eqqDaqEflaflldqleeelkk......eknkpkeeeeeedkselsde..............................aeekkkkknks 140
           +qqDaqEfl+ l+++l+ e+++                         +                               +++  ++++s
   Q: 298  SQQDAQEFLKLLMERLHLEINRrgrrapP------------------IlangsvvfllshgcsllplicgsdddranlMWKRYLEREDS 368
           ********************773322220..................1122223345666788888888888888888*********** PP
   S: 141  lisdlFqgqlksqikclecdnvssreepfldlslpvpgkeet.kkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPe 228
            i+dlF gqlks +kc++c+ +s+++e f+dlslp+p+k     k sl+dc++ ftkeeele+en+  c++c++k++++kkl+++++P+
   Q: 369  KIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAgGKVSLRDCFNLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPR 457
           *************************************887541456******************************************* PP
   S: 229  vLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVte 316
           +L l L+Rf  s +++s +k +  v+fpl+ L+l  f +++      +  Y+L+a ++HsGs++ GHY+a+++  + +W  ++Ds+V++
   Q: 458  ILGLDLNRF--SASRGSIKKSSVGVDFPLQrLSLGDFASDKAG----DPVYQLYALCNHSGSVHYGHYTALCRC-QTGWHVYNDSRVSP 539
           *********..55668999**********99*******99443....79*************************.777*********** PP
   S: 317  vkeeevleetgstaYvlfYk 336
           v+e++v +   s++YvlfY+
   Q: 540  VSENQVAS---SEGYVLFYQ 556
           ********...********8 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MPQASEHRLG RTREPPVNIQ ARVGSKLPFA PRARSKERRN PASGPNPMLR PLPPRPGPPD 60
ERLKKLELGR GRTSGPRPRG PLRADHGVPL PGSPPPAVAL PLPSRTNLAR SKSVSSGDLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCCAGG CCTCTGAGCA CCGCCTGGGC CGGACCCGAG AGCCACCTGT TAATATCCAG 60
GCCCGAGTGG GATCCAAGCT ACCATTTGCC CCCAGGGCCC GCAGCAAGGA GCGCAGAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004612	Anolis carolinensis	58.79	2.00e-169	588.00
IUUC-Ame-011548	Astyanax mexicanus	50.98	2.00e-101	362.00
IUUC-Cho-024836	Choloepus hoffmanni	94.30	2.00e-105	375.00
IUUC-Dre-028454	Danio rerio	52.38	4.00e-105	374.00
IUUC-Dno-029955	Dasypus novemcinctus	79.44	0.00e+00	908.00
IUUC-Gmo-038926	Gadus morhua	53.93	2.00e-101	362.00
IUUC-Gac-041331	Gasterosteus aculeatus	52.47	3.00e-104	371.00
IUUC-Lch-050539	Latimeria chalumnae	61.33	2.00e-101	362.00
IUUC-Loc-051808	Lepisosteus oculatus	54.72	5.00e-112	397.00
IUUC-Mmr-060913	Microcebus murinus	94.87	0.00e+00	934.00
IUUC-Oga-088007	Otolemur garnettii	76.33	0.00e+00	751.00
IUUC-Psi-093216	Pelodiscus sinensis	60.10	0.00e+00	654.00
IUUC-Pfo-096257	Poecilia formosa	49.30	1.00e-98	352.00
IUUC-Tni-120746	Tetraodon nigroviridis	51.04	4.00e-94	337.00
IUUC-Tbe-127465	Tupaia belangeri	97.21	3.00e-124	438.00
IUUC-Xtr-131989	Xenopus tropicalis	48.38	2.00e-122	432.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence