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Tag Content
UUCD2 ID IUUC-Mcc-055614
UUCD1 version UUC-MaM-00693
Ensembl Protein ID ENSMMUP00000014079.3
UniProt Accession F7FYD2; H9FSP2; F7FYD2_MACMU
Genbank Protein ID AFE77651.1
Protein Name Inhibitor of Bruton tyrosine kinase
Genbank Nucleotide ID JSUE03031448
Gene Name IBTK
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000010749.3 ENSMMUT00000015027.3 ENSMMUP00000014079.3
ENSMMUG00000010749.3 ENSMMUT00000069408.1 ENSMMUP00000058722.1
ENSMMUG00000010749.3 ENSMMUT00000073810.1 ENSMMUP00000057932.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 5.80e-26 91.7 564 640
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 2    DvilvvggeeffahkivLaasSsvFyalflmelees.............ksklmveikdvqpevfrallkFlYtgkld 66
           Dv+++vg++ f+ahk++La +S++F++lfl++ + s                   +++ v p+ f+ ll+F+Yt++ d
   Q: 564  DVTFQVGNRLFPAHKYILAVRSDFFQKLFLSDGSTSeftdiyrkdedsaG-CHLFVVEKVHPDMFEYLLQFIYTDTCD 640
           9*******************************99888*******996532.23344455***************9876 PP
   
Organism Macaca mulatta
Protein Sequence
(Fasta)
MNSPMPDCTS KCRSLKHALD VLSVVTKGSE NQIKAFLSSH CYNAATIKDV FGRNALHLVS 60
SCGKKGVLDW LIQKGVDLLV KDKESGWTAL HRSIFYGHID CVWSLLKHGV SLYIQDKEGL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mcc-055614|E3,BTB_Other|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCCCTTCCT CCACATCCCC CTTCCCGATT CTTGTAGTCG CGGCTGGGTT GCAGCCGCCT 60
GCCGAACTGA CCCGGCTCTG GGGACCGGCC CCTCTGGCGC CGTTCGGTTT CTCTTATTGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mcc-055614|E3,BTB_Other|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR000210--BTB/POZ_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
IPR011333--SKP1/BTB/POZ
PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50097--BTB
PS50012--RCC1_3
Pfam

PF12796--Ank_2
PF00651--BTB
PF00415--RCC1
SMART

SM00248--ANK
SM00225--BTB
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0016301--F:kinase activity
GO:0030292--F:protein tyrosine kinase inhibitor activity
GO:0051209--P:release of sequestered calcium ion into cytosol
KEGG mcc:693559
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000696 Aegilops tauschii 30.59 3.00e-40 161.00
IUUC-Aml-001765 Ailuropoda melanoleuca 89.82 0.00e+00 2362.00
IUUC-Atr-003012 Amborella trichopoda 31.18 6.00e-32 133.00
IUUC-Apl-003868 Anas platyrhynchos 72.07 0.00e+00 1943.00
IUUC-Aca-004897 Anolis carolinensis 67.06 0.00e+00 1711.00
IUUC-Aly-005989 Arabidopsis lyrata 29.20 2.00e-35 144.00
IUUC-Ath-007268 Arabidopsis thaliana 28.80 2.00e-34 141.00
IUUC-Ago-007942 Ashbya gossypii 24.78 8.00e-11 63.20
IUUC-Acl-008353 Aspergillus clavatus 24.67 2.00e-32 135.00
IUUC-Afl-008409 Aspergillus flavus 26.48 8.00e-36 146.00
IUUC-Afu-008944 Aspergillus fumigatus 25.71 2.00e-33 138.00
IUUC-Ani-009309 Aspergillus nidulans 25.55 1.00e-31 132.00
IUUC-Ang-009872 Aspergillus niger 22.90 3.00e-45 178.00
IUUC-Aor-010054 Aspergillus oryzae 26.48 6.00e-36 147.00
IUUC-Ate-010319 Aspergillus terreus 21.99 5.00e-12 67.80
IUUC-Ame-010972 Astyanax mexicanus 57.02 0.00e+00 1420.00
IUUC-Bgr-012036 Blumeria graminis 26.14 1.00e-29 125.00
IUUC-Bta-012491 Bos taurus 89.96 0.00e+00 2375.00
IUUC-Bci-013874 Botrytis cinerea 26.00 7.00e-34 140.00
IUUC-Bdi-014094 Brachypodium distachyon 29.76 5.00e-40 160.00
IUUC-Bol-015876 Brassica oleracea 30.33 3.00e-31 130.00
IUUC-Bra-017155 Brassica rapa 30.23 7.00e-34 139.00
IUUC-Cja-019928 Callithrix jacchus 94.24 0.00e+00 2492.00
IUUC-Cfa-021191 Canis familiaris 90.55 0.00e+00 2434.00
IUUC-Cpo-021893 Cavia porcellus 85.88 0.00e+00 1467.00
IUUC-Csa-023410 Chlorocebus sabaeus 99.33 0.00e+00 2664.00
IUUC-Cho-024939 Choloepus hoffmanni 81.62 0.00e+00 1912.00
IUUC-Cin-025713 Ciona intestinalis 34.05 5.00e-141 495.00
IUUC-Cgl-026577 Colletotrichum gloeosporioides 23.70 2.00e-14 75.90
IUUC-Cne-026961 Cryptococcus neoformans 31.76 6.00e-22 100.00
IUUC-Cme-027274 Cyanidioschyzon merolae 30.62 8.00e-12 66.60
IUUC-Dre-027465 Danio rerio 54.83 0.00e+00 1371.00
IUUC-Dno-029885 Dasypus novemcinctus 89.96 0.00e+00 2391.00
IUUC-Dor-030105 Dipodomys ordii 86.09 0.00e+00 910.00
IUUC-Dse-031213 Dothistroma septosporum 28.64 3.00e-37 151.00
IUUC-Dme-031915 Drosophila melanogaster 27.21 2.00e-68 254.00
IUUC-Ete-033002 Echinops telfairi 75.15 0.00e+00 1889.00
IUUC-Eca-034271 Equus caballus 91.06 0.00e+00 2434.00
IUUC-Eeu-034921 Erinaceus europaeus 82.17 0.00e+00 2142.00
IUUC-Fca-036135 Felis catus 88.16 0.00e+00 2394.00
IUUC-Fal-036815 Ficedula albicollis 72.13 0.00e+00 1833.00
IUUC-Fox-037821 Fusarium oxysporum 25.07 1.00e-19 92.80
IUUC-Fso-038316 Fusarium solani 25.84 1.00e-21 99.80
IUUC-Gmo-038841 Gadus morhua 55.53 0.00e+00 1365.00
IUUC-Ggr-040105 Gaeumannomyces graminis 27.15 1.00e-20 96.30
IUUC-Gga-040756 Gallus gallus 72.10 0.00e+00 1870.00
IUUC-Gac-041957 Gasterosteus aculeatus 57.13 0.00e+00 1430.00
IUUC-Gma-043801 Glycine max 29.92 8.00e-42 166.00
IUUC-Ggo-044737 Gorilla gorilla 94.39 0.00e+00 2486.00
IUUC-Hsa-046756 Homo sapiens 97.86 0.00e+00 2597.00
IUUC-Itr-048204 Ictidomys tridecemlineatus 91.36 0.00e+00 2415.00
IUUC-Lch-050082 Latimeria chalumnae 74.58 1.00e-80 292.00
IUUC-Lpe-050709 Leersia perrieri 31.31 1.00e-41 166.00
IUUC-Loc-052669 Lepisosteus oculatus 62.23 0.00e+00 1603.00
IUUC-Lma-053227 Leptosphaeria maculans 27.07 2.00e-37 152.00
IUUC-Laf-053898 Loxodonta africana 89.88 0.00e+00 2358.00
IUUC-Meu-056803 Macropus eugenii 54.51 0.00e+00 1130.00
IUUC-Mor-056973 Magnaporthe oryzae 23.41 3.00e-27 118.00
IUUC-Mpo-057627 Magnaporthe poae 21.89 2.00e-25 112.00
IUUC-Mtr-058718 Medicago truncatula 30.57 1.00e-40 162.00
IUUC-Mla-058948 Melampsora laricipopulina 28.54 8.00e-30 126.00
IUUC-Mga-059344 Meleagris gallopavo 71.40 0.00e+00 1833.00
IUUC-Mvi-060265 Microbotryum violaceum 26.49 2.00e-28 122.00
IUUC-Mmr-061025 Microcebus murinus 92.39 0.00e+00 2440.00
IUUC-Mdo-061884 Monodelphis domestica 77.30 0.00e+00 2028.00
IUUC-Mmu-063492 Mus musculus 85.30 0.00e+00 2221.00
IUUC-Mac-065442 Musa acuminata 32.21 2.00e-37 151.00
IUUC-Mpu-065714 Mustela putorius furo 89.44 0.00e+00 2373.00
IUUC-Mlu-068229 Myotis lucifugus 87.97 0.00e+00 2308.00
IUUC-Nfi-068585 Neosartorya fischeri 25.51 2.00e-34 142.00
IUUC-Ncr-068789 Neurospora crassa 28.68 1.00e-18 89.40
IUUC-Nle-070017 Nomascus leucogenys 97.71 0.00e+00 2594.00
IUUC-Opr-070430 Ochotona princeps 75.31 0.00e+00 1933.00
IUUC-Ont-071686 Oreochromis niloticus 59.09 0.00e+00 1487.00
IUUC-Oan-073539 Ornithorhynchus anatinus 75.48 0.00e+00 1841.00
IUUC-Ocu-074076 Oryctolagus cuniculus 90.40 0.00e+00 2377.00
IUUC-Oba-075204 Oryza barthii 31.43 2.00e-42 168.00
IUUC-Obr-076797 Oryza brachyantha 31.06 1.00e-40 162.00
IUUC-Ogl-077619 Oryza glaberrima 31.73 2.00e-43 171.00
IUUC-Ogu-078961 Oryza glumaepatula 31.25 7.00e-43 169.00
IUUC-Oin-079261 Oryza indica 31.25 9.00e-43 169.00
IUUC-Olo-080829 Oryza longistaminata 31.25 5.00e-43 169.00
IUUC-Ome-081599 Oryza meridionalis 31.04 2.00e-42 168.00
IUUC-Oni-082029 Oryza nivara 31.25 3.00e-42 167.00
IUUC-Opu-083657 Oryza punctata 31.59 5.00e-42 166.00
IUUC-Oru-084765 Oryza rufipogon 31.25 8.00e-43 169.00
IUUC-Osa-086136 Oryza sativa 31.25 4.00e-42 166.00
IUUC-Ola-087419 Oryzias latipes 59.77 0.00e+00 1508.00
IUUC-Oga-088885 Otolemur garnettii 88.03 0.00e+00 2318.00
IUUC-Oar-090361 Ovis aries 89.07 0.00e+00 2352.00
IUUC-Ptr-091424 Pan troglodytes 97.71 0.00e+00 2597.00
IUUC-Pan-092557 Papio anubis 98.15 0.00e+00 2607.00
IUUC-Psi-093980 Pelodiscus sinensis 72.97 0.00e+00 1914.00
IUUC-Pno-094989 Phaeosphaeria nodorum 28.10 2.00e-31 132.00
IUUC-Ppa-095929 Physcomitrella patens 33.23 3.00e-40 160.00
IUUC-Pfo-096296 Poecilia formosa 56.64 0.00e+00 1421.00
IUUC-Pab-097552 Pongo abelii 97.71 0.00e+00 2597.00
IUUC-Pop-099124 Populus trichocarpa 29.86 9.00e-40 159.00
IUUC-Pca-100417 Procavia capensis 84.30 0.00e+00 926.00
IUUC-Ppe-101574 Prunus persica 29.61 1.00e-37 152.00
IUUC-Pva-102906 Pteropus vampyrus 85.66 0.00e+00 2242.00
IUUC-Pgr-103405 Puccinia graminis 28.54 3.00e-32 135.00
IUUC-Ptt-103743 Puccinia triticina 29.24 4.00e-36 147.00
IUUC-Pte-104407 Pyrenophora teres 27.07 2.00e-38 155.00
IUUC-Pyt-104646 Pyrenophora triticirepentis 27.07 3.00e-38 155.00
IUUC-Rno-105118 Rattus norvegicus 83.46 0.00e+00 2161.00
IUUC-Sha-106797 Sarcophilus harrisii 76.80 0.00e+00 1982.00
IUUC-Sja-107740 Schizosaccharomyces japonicus 28.77 6.00e-42 166.00
IUUC-Spo-108090 Schizosaccharomyces pombe 33.15 3.00e-39 157.00
IUUC-Ssl-108513 Sclerotinia sclerotiorum 24.45 2.00e-27 118.00
IUUC-Smo-109576 Selaginella moellendorffii 30.43 4.00e-37 150.00
IUUC-Sit-110676 Setaria italica 30.27 7.00e-42 166.00
IUUC-Sly-111572 Solanum lycopersicum 29.11 2.00e-31 131.00
IUUC-Sar-113437 Sorex araneus 79.39 0.00e+00 2024.00
IUUC-Sbi-114124 Sorghum bicolor 29.90 1.00e-39 158.00
IUUC-Sre-114999 Sporisorium reilianum 28.75 1.00e-33 139.00
IUUC-Ssc-116088 Sus scrofa 89.88 0.00e+00 2293.00
IUUC-Tgu-116854 Taeniopygia guttata 72.11 0.00e+00 1877.00
IUUC-Tru-117552 Takifugu rubripes 56.98 0.00e+00 1429.00
IUUC-Tsy-118821 Tarsius syrichta 86.68 0.00e+00 2024.00
IUUC-Tni-119891 Tetraodon nigroviridis 57.09 0.00e+00 1436.00
IUUC-Tca-121015 Theobroma cacao 29.66 3.00e-37 150.00
IUUC-Tre-122202 Trichoderma reesei 26.42 2.00e-23 105.00
IUUC-Tvi-122439 Trichoderma virens 26.29 5.00e-22 100.00
IUUC-Tae-123606 Triticum aestivum 30.86 7.00e-41 162.00
IUUC-Tur-126077 Triticum urartu 30.37 3.00e-39 157.00
IUUC-Tme-127029 Tuber melanosporum 29.33 9.00e-28 120.00
IUUC-Tbe-127811 Tupaia belangeri 78.37 0.00e+00 1217.00
IUUC-Ttr-128664 Tursiops truncatus 85.32 0.00e+00 2017.00
IUUC-Uma-129427 Ustilago maydis 29.00 7.00e-33 137.00
IUUC-Vda-129791 Verticillium dahliae 26.30 1.00e-21 99.80
IUUC-Vpa-130558 Vicugna pacos 83.67 0.00e+00 2137.00
IUUC-Vvi-131602 Vitis vinifera 34.50 4.00e-37 150.00
IUUC-Xtr-131965 Xenopus tropicalis 62.10 0.00e+00 1544.00
IUUC-Xma-133569 Xiphophorus maculatus 56.64 0.00e+00 1429.00
IUUC-Yli-134409 Yarrowia lipolytica 30.88 4.00e-26 114.00
IUUC-Zma-135450 Zea mays 30.04 3.00e-42 167.00
Created Date 25-Jun-2017

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