iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000008288.2	ENSCJAT00000016227.2	ENSCJAP00000015365.2
ENSCJAG00000008288.2	ENSCJAT00000016251.2	ENSCJAP00000015384.2
ENSCJAG00000008288.2	ENSCJAT00000016214.2	ENSCJAP00000015355.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.80e-12	46.9	65	122

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 65   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 122
           67899************************.*********98..788899*********997 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

XETGFNIFTQ HGECGSRREG EREAGGGLSE ALHRPYGCDL EPQALNEAIR WSSKENLLGA 60
TESDPNLFVA LYDFVASGDN TLSITKGEKL RVLGYNQNGE WSEVRSKNGQ GWVPSNYITP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NCAGAGACCG GCTTCAATAT CTTCACCCAG CATGGTGAGT GTCCGGGAGC CGGCGTGAGG 60
GCGAGCGGGA GGCCGGGGGT GGGGTCTGGG CAGGGTGGCT GGCGGACGAG CTGCCCTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005623--C:cell
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0030145--F:manganese ion binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0071300--P:cellular response to retinoic acid
GO:0007204--P:positive regulation of cytosolic calcium ion concentration
GO:0010976--P:positive regulation of neuron projection development
GO:0051353--P:positive regulation of oxidoreductase activity
GO:0010863--P:positive regulation of phospholipase C activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002263	Ailuropoda melanoleuca	96.58	0.00e+00	2002.00
IUUC-Atr-002778	Amborella trichopoda	32.49	1.00e-22	102.00
IUUC-Apl-003389	Anas platyrhynchos	85.50	0.00e+00	1732.00
IUUC-Ame-010629	Astyanax mexicanus	58.45	0.00e+00	1083.00
IUUC-Bta-013370	Bos taurus	94.65	0.00e+00	1997.00
IUUC-Cfa-020398	Canis familiaris	97.44	0.00e+00	1248.00
IUUC-Cpo-022367	Cavia porcellus	89.22	0.00e+00	1823.00
IUUC-Csa-023386	Chlorocebus sabaeus	98.11	0.00e+00	2036.00
IUUC-Cho-024714	Choloepus hoffmanni	91.64	0.00e+00	1864.00
IUUC-Dre-027741	Danio rerio	66.72	0.00e+00	1400.00
IUUC-Dno-029246	Dasypus novemcinctus	94.64	0.00e+00	1969.00
IUUC-Dor-030416	Dipodomys ordii	87.29	0.00e+00	1822.00
IUUC-Ete-032899	Echinops telfairi	76.96	0.00e+00	845.00
IUUC-Eca-033387	Equus caballus	96.25	0.00e+00	1964.00
IUUC-Eeu-035058	Erinaceus europaeus	85.03	0.00e+00	1845.00
IUUC-Fca-036578	Felis catus	89.73	0.00e+00	1788.00
IUUC-Fal-037491	Ficedula albicollis	88.32	0.00e+00	1863.00
IUUC-Gmo-038509	Gadus morhua	77.36	0.00e+00	1132.00
IUUC-Gga-040638	Gallus gallus	85.84	0.00e+00	1809.00
IUUC-Gac-042550	Gasterosteus aculeatus	69.50	0.00e+00	1351.00
IUUC-Ggo-044487	Gorilla gorilla	96.58	0.00e+00	2048.00
IUUC-Hsa-046636	Homo sapiens	96.67	0.00e+00	2048.00
IUUC-Itr-048685	Ictidomys tridecemlineatus	95.45	0.00e+00	1985.00
IUUC-Lch-049530	Latimeria chalumnae	77.25	0.00e+00	1595.00
IUUC-Loc-051933	Lepisosteus oculatus	71.09	0.00e+00	1449.00
IUUC-Laf-053802	Loxodonta africana	94.49	0.00e+00	2039.00
IUUC-Mcc-054836	Macaca mulatta	96.67	0.00e+00	2074.00
IUUC-Mga-059277	Meleagris gallopavo	87.86	0.00e+00	1821.00
IUUC-Mmr-061206	Microcebus murinus	94.74	0.00e+00	1924.00
IUUC-Mdo-062281	Monodelphis domestica	93.16	0.00e+00	1215.00
IUUC-Mmu-063847	Mus musculus	92.56	0.00e+00	1894.00
IUUC-Mpu-066309	Mustela putorius furo	95.98	0.00e+00	1262.00
IUUC-Mlu-068070	Myotis lucifugus	96.04	0.00e+00	1986.00
IUUC-Nle-070062	Nomascus leucogenys	96.75	0.00e+00	1274.00
IUUC-Opr-070534	Ochotona princeps	90.76	0.00e+00	1072.00
IUUC-Ont-072440	Oreochromis niloticus	71.25	0.00e+00	1251.00
IUUC-Oan-073526	Ornithorhynchus anatinus	88.77	0.00e+00	1776.00
IUUC-Ocu-074051	Oryctolagus cuniculus	95.23	0.00e+00	1889.00
IUUC-Ola-086752	Oryzias latipes	95.05	0.00e+00	914.00
IUUC-Oga-088767	Otolemur garnettii	90.66	0.00e+00	1800.00
IUUC-Oar-089800	Ovis aries	96.13	0.00e+00	1982.00
IUUC-Ptr-090857	Pan troglodytes	96.90	0.00e+00	1274.00
IUUC-Pan-092279	Papio anubis	96.49	0.00e+00	2038.00
IUUC-Psi-093573	Pelodiscus sinensis	88.60	0.00e+00	1795.00
IUUC-Pfo-096543	Poecilia formosa	74.44	0.00e+00	1152.00
IUUC-Pab-097949	Pongo abelii	96.31	0.00e+00	1996.00
IUUC-Pca-100370	Procavia capensis	93.86	0.00e+00	1460.00
IUUC-Pva-103220	Pteropus vampyrus	86.75	0.00e+00	1705.00
IUUC-Rno-105924	Rattus norvegicus	91.04	0.00e+00	1889.00
IUUC-Sha-107114	Sarcophilus harrisii	88.21	0.00e+00	1390.00
IUUC-Sit-110219	Setaria italica	29.48	5.00e-20	93.20
IUUC-Ssc-115968	Sus scrofa	94.48	0.00e+00	2038.00
IUUC-Tgu-117301	Taeniopygia guttata	87.87	0.00e+00	1805.00
IUUC-Tru-118410	Takifugu rubripes	67.51	0.00e+00	1377.00
IUUC-Tni-119991	Tetraodon nigroviridis	66.81	0.00e+00	1384.00
IUUC-Tbe-127362	Tupaia belangeri	90.27	0.00e+00	1810.00
IUUC-Ttr-129291	Tursiops truncatus	95.95	0.00e+00	1996.00
IUUC-Vpa-130800	Vicugna pacos	96.35	0.00e+00	1559.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence