iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	4.60e-12	46.5	34	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgklde 67
           +Dv++ v+g++f+ah++vLaa+Ss+F++ + ++ +    +l++++ + v  + f+ l++F Yt kl +
   Q: 34   CDVTVLVEGQQFRAHRSVLAACSSYFHSRIVGQTDA---ELTITLPQeVTVKGFEPLIQFAYTAKLIL 98
           8*****************************777664...579***966*****************987 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSVSESAVFA YESSVHSTNV LLSLNDQRKK DVLCDVTVLV EGQQFRAHRS VLAACSSYFH 60
SRIVGQTDAE LTITLPQEVT VKGFEPLIQF AYTAKLILSK DNVDEVCKCV EFLSVHNIEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGACGGGCG GCCGTCCGCG CGGAGGGAGT GAGTCACCTG ACCGCCGCTT GCCGCCTGCA 60
GTCGGGCCGT GCCGCGCCTC GGCTCCGGTG AGTGGCTCGG ACGGTGCGGG CTGCCGTCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR000210--BTB/POZ_dom
IPR004827--bZIP
IPR004826--bZIP_Maf
IPR011333--SKP1/BTB/POZ
IPR008917--TF_DNA-bd

PROSITE

PS50097--BTB
PS50217--BZIP
PS00036--BZIP_BASIC

Pfam

PF00651--BTB
PF03131--bZIP_Maf

SMART

SM00338--BRLZ
SM00225--BTB

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000980--F:RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0001205--F:transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001206--F:transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0006281--P:DNA repair
GO:0016567--P:protein ubiquitination
GO:0061418--P:regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0000083--P:regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000117--P:regulation of transcription involved in G2/M transition of mitotic cell cycle
GO:0006366--P:transcription from RNA polymerase II promoter

KEGG

rno:304127

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002273	Ailuropoda melanoleuca	76.38	0.00e+00	1055.00
IUUC-Apl-003378	Anas platyrhynchos	63.95	0.00e+00	754.00
IUUC-Aca-004992	Anolis carolinensis	52.60	0.00e+00	639.00
IUUC-Ani-009267	Aspergillus nidulans	35.56	4.60e-01	30.00
IUUC-Ame-011817	Astyanax mexicanus	34.48	1.00e-75	277.00
IUUC-Bta-012599	Bos taurus	73.22	0.00e+00	1045.00
IUUC-Cja-019778	Callithrix jacchus	78.78	0.00e+00	1114.00
IUUC-Cfa-020459	Canis familiaris	77.60	0.00e+00	1099.00
IUUC-Cpo-021433	Cavia porcellus	76.42	0.00e+00	1077.00
IUUC-Csa-023346	Chlorocebus sabaeus	79.86	0.00e+00	1113.00
IUUC-Cho-024893	Choloepus hoffmanni	75.95	0.00e+00	1084.00
IUUC-Dno-029607	Dasypus novemcinctus	77.94	0.00e+00	1103.00
IUUC-Dor-031026	Dipodomys ordii	55.34	9.00e-123	434.00
IUUC-Ete-032304	Echinops telfairi	67.65	0.00e+00	890.00
IUUC-Eca-033379	Equus caballus	74.84	0.00e+00	865.00
IUUC-Eeu-035358	Erinaceus europaeus	75.71	0.00e+00	854.00
IUUC-Fca-035499	Felis catus	77.47	0.00e+00	1104.00
IUUC-Fal-037171	Ficedula albicollis	61.42	0.00e+00	692.00
IUUC-Gga-041169	Gallus gallus	60.23	0.00e+00	801.00
IUUC-Ggo-044485	Gorilla gorilla	79.05	0.00e+00	1122.00
IUUC-Hsa-046202	Homo sapiens	79.46	0.00e+00	1106.00
IUUC-Itr-047970	Ictidomys tridecemlineatus	78.81	0.00e+00	1130.00
IUUC-Loc-052298	Lepisosteus oculatus	46.44	2.00e-57	217.00
IUUC-Laf-054320	Loxodonta africana	74.55	0.00e+00	854.00
IUUC-Mcc-055644	Macaca mulatta	80.14	0.00e+00	1115.00
IUUC-Mga-059196	Meleagris gallopavo	60.05	0.00e+00	793.00
IUUC-Mmr-061053	Microcebus murinus	80.30	0.00e+00	1142.00
IUUC-Mdo-062091	Monodelphis domestica	58.26	0.00e+00	709.00
IUUC-Mmu-063403	Mus musculus	92.42	0.00e+00	1299.00
IUUC-Mpu-065768	Mustela putorius furo	76.64	0.00e+00	1071.00
IUUC-Mlu-067451	Myotis lucifugus	69.88	0.00e+00	938.00
IUUC-Nle-069507	Nomascus leucogenys	79.32	0.00e+00	1129.00
IUUC-Oan-073692	Ornithorhynchus anatinus	65.09	5.00e-97	348.00
IUUC-Ocu-074850	Oryctolagus cuniculus	81.11	0.00e+00	1031.00
IUUC-Oga-088762	Otolemur garnettii	77.90	0.00e+00	1103.00
IUUC-Oar-089511	Ovis aries	77.06	0.00e+00	977.00
IUUC-Ptr-091232	Pan troglodytes	79.19	0.00e+00	1140.00
IUUC-Pan-091803	Papio anubis	80.14	0.00e+00	1117.00
IUUC-Pab-098303	Pongo abelii	79.19	0.00e+00	1123.00
IUUC-Pca-100147	Procavia capensis	67.61	0.00e+00	635.00
IUUC-Pva-102920	Pteropus vampyrus	77.72	0.00e+00	1108.00
IUUC-Sha-107059	Sarcophilus harrisii	64.28	0.00e+00	832.00
IUUC-Sar-113133	Sorex araneus	70.08	7.00e-146	511.00
IUUC-Ssc-115328	Sus scrofa	75.23	0.00e+00	1041.00
IUUC-Tgu-116625	Taeniopygia guttata	60.90	0.00e+00	803.00
IUUC-Tru-118149	Takifugu rubripes	41.38	1.00e-44	174.00
IUUC-Tni-120068	Tetraodon nigroviridis	57.69	6.00e-38	152.00
IUUC-Ttr-128805	Tursiops truncatus	75.71	0.00e+00	761.00
IUUC-Xtr-132494	Xenopus tropicalis	44.65	6.00e-159	554.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence