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Tag Content
UUCD2 ID IUUC-Mlu-067139
UUCD1 version UUC-MyL-01188
Ensembl Protein ID ENSMLUP00000010198.2
UniProt Accession G1PHP0; G1PHP0_MYOLU
Genbank Protein ID ENSMLUP00000010198
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAPE02032125
Gene Name USP25
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMLUG00000011144.2 ENSMLUT00000011189.2 ENSMLUP00000010198.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 2.80e-63 214.2 154 640
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +GlkN+gNtC++ +v+Q+L+n+ e+r+l+l+    ++ ++l+++++++++ +++++l+ lf+ l+ +k+k+v+p++ +++lk++ ++ s
   Q: 154  VGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNykppSNAQDLPRNQKEHRNLPFMCELRYLFALLVGTKRKYVDPSRAVEILKDAFKS-S 241
           6******************************99988889999999999999*******************************99998.9 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
            ++qqD++Ef++ lld le+++++                  + +ee +++k k+++++lF g++    + +  +++ + +e f +++l
   Q: 242  DSQQQDVSEFTHKLLDWLEDAFQM------------------KAEEETDEEKPKNPMVELFYGRFLAVGVLE--GKKFENTEMFGQYPL 310
           9*********************33..................123456788999************777664..444556899****** PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           +v+g +     +l++cLe+ + e e+e+   +++e+  k+    +++++++lP+vL+++L+Rf+f+++ +++eki++k+efp+ L l++
   Q: 311  QVNGFK-----DLHECLEAAMIEGEIES---LHSENSGKS---GQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDR 388
           ******.....9**************96...999998865...589******************************************* PP
   S: 264  fcts..................................................................................... 267
           ++++                                                                                     
   Q: 389  YMHRnreitrikreeikrlkdyltvlqqrlerylsygsgpkrfplvdvlqyalefasskpvctspvddidassppsgsvpsqalpstme 477
           ****8888888888888888888888777777777777777777777777777777777777777777777777777777666666666 PP
   S: 268  .........peekqke......................................................................... 274
                    p     +                                                                         
   Q: 478  qqgaasselP-----Stsptsiaaissrsmihkpftqsrippdlpmhpaprhiteeelsvlesclhrwrteiendtrdlqesisrihrt 561
           5555555550.....05555555555555555555556666666666666666666666666777777777777777777788888888 PP
   S: 275  ...........kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                      ++ Y+L+av+vH+G+++ GHY+ay+ +++++ W++++D  Vt +++ee ++++      ++aY+l+Y 
   Q: 562  ielmysdksmiQVPYRLHAVLVHEGQANAGHYWAYIFDHHENrWMKYNDIAVTRSSWEELVRDSFggyrnASAYCLMYI 640
           88888888888**************************966656***************99997779************6 PP
   
Organism Myotis lucifugus
Protein Sequence
(Fasta)
HQQTFLNQLR EITGINDTQI LQQALKDSNG NLELAVAFLT AKNAKPPQQE ETAYYQTALP 60
SNDRYISVGS QADANVIDLT GDDKDDLQRA IALSLAESNR AFRETGITDE EQAISRVLEA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mlu-067139|DUB,USP|Myotis lucifugus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CATCAGCAGA CGTTTTTGAA TCAGCTGAGA GAAATCACTG GGATTAATGA CACCCAGATA 60
CTACAGCAAG CCTTGAAGGT ATGACCTCTG TTTTATGACA TAGTTCATGT TAACCCCTTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mlu-067139|DUB,USP|Myotis lucifugus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR003903--UIM_dom
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
PF02809--UIM
SMART

SM00726--UIM
Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1904293--P:negative regulation of ERAD pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001340 Ailuropoda melanoleuca 92.81 0.00e+00 1931.00
IUUC-Apl-004030 Anas platyrhynchos 82.82 0.00e+00 1801.00
IUUC-Aca-004753 Anolis carolinensis 64.50 0.00e+00 988.00
IUUC-Ani-009503 Aspergillus nidulans 33.96 1.00e-11 65.50
IUUC-Ame-010624 Astyanax mexicanus 70.56 0.00e+00 1084.00
IUUC-Bta-013166 Bos taurus 96.15 0.00e+00 1943.00
IUUC-Cel-018346 Caenorhabditis elegans 27.37 3.00e-29 124.00
IUUC-Cja-019150 Callithrix jacchus 94.38 0.00e+00 1391.00
IUUC-Cfa-020649 Canis familiaris 95.28 0.00e+00 1406.00
IUUC-Cpo-021807 Cavia porcellus 92.62 0.00e+00 2012.00
IUUC-Csa-023388 Chlorocebus sabaeus 94.25 0.00e+00 1420.00
IUUC-Cho-024343 Choloepus hoffmanni 82.93 0.00e+00 970.00
IUUC-Cin-025302 Ciona intestinalis 37.33 6.00e-95 341.00
IUUC-Csv-025911 Ciona savignyi 35.67 6.00e-130 458.00
IUUC-Cgl-026575 Colletotrichum gloeosporioides 55.32 2.00e-10 62.00
IUUC-Cme-027167 Cyanidioschyzon merolae 24.57 6.00e-14 73.20
IUUC-Dre-028016 Danio rerio 76.95 0.00e+00 1170.00
IUUC-Dno-029495 Dasypus novemcinctus 92.16 0.00e+00 1394.00
IUUC-Dor-030948 Dipodomys ordii 80.91 0.00e+00 1410.00
IUUC-Ete-032323 Echinops telfairi 93.60 5.00e-170 592.00
IUUC-Eca-033214 Equus caballus 94.83 0.00e+00 951.00
IUUC-Fca-035876 Felis catus 95.57 0.00e+00 1967.00
IUUC-Fal-036762 Ficedula albicollis 84.08 0.00e+00 1115.00
IUUC-Gmo-039490 Gadus morhua 72.29 0.00e+00 1509.00
IUUC-Gga-040817 Gallus gallus 85.34 0.00e+00 1335.00
IUUC-Gac-042473 Gasterosteus aculeatus 71.99 0.00e+00 1541.00
IUUC-Ggo-044939 Gorilla gorilla 91.60 0.00e+00 1863.00
IUUC-Hsa-046204 Homo sapiens 96.06 0.00e+00 1924.00
IUUC-Kpa-049349 Komagataella pastoris 28.12 3.00e-10 61.60
IUUC-Lch-049572 Latimeria chalumnae 79.08 0.00e+00 1212.00
IUUC-Loc-052070 Lepisosteus oculatus 78.66 0.00e+00 1191.00
IUUC-Lma-053078 Leptosphaeria maculans 30.56 4.00e-12 67.40
IUUC-Laf-054426 Loxodonta africana 95.86 0.00e+00 1817.00
IUUC-Mcc-055858 Macaca mulatta 94.38 0.00e+00 1422.00
IUUC-Mga-059808 Meleagris gallopavo 85.47 0.00e+00 1816.00
IUUC-Mmr-060987 Microcebus murinus 96.46 0.00e+00 1405.00
IUUC-Mmu-064245 Mus musculus 92.69 0.00e+00 1940.00
IUUC-Mpu-066304 Mustela putorius furo 95.41 0.00e+00 1404.00
IUUC-Nle-069075 Nomascus leucogenys 95.96 0.00e+00 1920.00
IUUC-Ont-072150 Oreochromis niloticus 74.91 0.00e+00 1172.00
IUUC-Oan-073054 Ornithorhynchus anatinus 79.14 0.00e+00 1667.00
IUUC-Ocu-074102 Oryctolagus cuniculus 92.67 0.00e+00 1399.00
IUUC-Ola-086529 Oryzias latipes 69.57 0.00e+00 1471.00
IUUC-Oga-088939 Otolemur garnettii 95.58 0.00e+00 1961.00
IUUC-Oar-090266 Ovis aries 95.94 0.00e+00 1408.00
IUUC-Ptr-090546 Pan troglodytes 95.96 0.00e+00 1923.00
IUUC-Pan-092311 Papio anubis 94.25 0.00e+00 1420.00
IUUC-Psi-093459 Pelodiscus sinensis 89.89 0.00e+00 1157.00
IUUC-Pfo-096726 Poecilia formosa 74.56 0.00e+00 1159.00
IUUC-Pab-097608 Pongo abelii 93.10 0.00e+00 1904.00
IUUC-Pca-100718 Procavia capensis 90.87 0.00e+00 1219.00
IUUC-Pva-103150 Pteropus vampyrus 92.71 0.00e+00 1471.00
IUUC-Rno-105727 Rattus norvegicus 93.27 0.00e+00 1907.00
IUUC-Sha-107051 Sarcophilus harrisii 88.55 0.00e+00 1842.00
IUUC-Sar-113097 Sorex araneus 85.53 0.00e+00 1795.00
IUUC-Ssc-115877 Sus scrofa 94.03 0.00e+00 1939.00
IUUC-Tgu-117473 Taeniopygia guttata 78.75 0.00e+00 1674.00
IUUC-Tru-118135 Takifugu rubripes 66.70 0.00e+00 1386.00
IUUC-Tsy-119471 Tarsius syrichta 88.49 0.00e+00 1758.00
IUUC-Tni-120139 Tetraodon nigroviridis 68.11 0.00e+00 1308.00
IUUC-Tbe-127549 Tupaia belangeri 89.26 0.00e+00 1850.00
IUUC-Ttr-128896 Tursiops truncatus 89.26 0.00e+00 1853.00
IUUC-Uma-129338 Ustilago maydis 24.59 1.00e-13 72.80
IUUC-Vpa-130500 Vicugna pacos 92.46 0.00e+00 1314.00
IUUC-Xtr-132896 Xenopus tropicalis 80.35 0.00e+00 1705.00
IUUC-Xma-133349 Xiphophorus maculatus 74.18 0.00e+00 1578.00
Created Date 25-Jun-2017

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