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Tag Content
UUCD2 ID IUUC-Nle-069075
UUCD1 version UUC-NoL-01071
Ensembl Protein ID ENSNLEP00000002431.1
UniProt Accession G1QNB5; G1QNB5_NOMLE
Genbank Protein ID ENSNLEP00000002431
Protein Name Uncharacterized protein
Genbank Nucleotide ID ADFV01018324
Gene Name USP25
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSNLEG00000001900.1 ENSNLET00000002561.1 ENSNLEP00000002431.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 5.40e-64 216.5 169 655
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +GlkN+gNtC++ +v+Q+L+n+ e+r+l+l+    ++ ++l+++++++++ +++++l+ lf+ l+ +k+k+v+p++ +++lk++ ++ +
   Q: 169  VGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNykppSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTKRKYVDPSRAVEILKDAFKS-N 256
           6******************************99988889999999999999*******************************99997.9 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
            ++qqD++Ef++ lld le+++++                  + +ee +++k k+++++lF g++    + +  +++ + +e f +++l
   Q: 257  DSQQQDVSEFTHKLLDWLEDAFQM------------------KAEEETDEEKPKNPMVELFYGRFLAVGVLE--GKKFENTEMFGQYPL 325
           **********************33..................123456788999************777664..444556899****** PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           +v+g +     +l++cLe+ + e e+e+   +++e+  k+    +++++++lP+vL+++L+Rf+f+++ +++eki++k+efp+ L l++
   Q: 326  QVNGFK-----DLHECLEAAMIEGEIES---LHSENSGKS---GQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDR 403
           ******.....9**************96...999998865...589******************************************* PP
   S: 264  fcts..................................................................................... 267
           ++++                                                                                     
   Q: 404  YMHRnreitrikreeikrlkdyltvlqqrlerylsygsgpkrfplvdvlqyalefasskpvctspvddidassppsgsipsqtlpstte 492
           ****8888888888888888888888888888888888888888888888888777777777777777777777777777777766555 PP
   S: 268  ......peekqke............................................................................ 274
                 +     e                                                                            
   Q: 493  qqgapsS-----Elpstspssvaaissrsvihkpftqsrippdlpmhpaprhiteeelsvlesclhrwrteiendtrdlqesisrihrt 576
           5555550.....05555555556666666666666666666666666666666666666677777777777777777777888888888 PP
   S: 275  ...........kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                      ++ Y+L+av+vH+G+++ GHY+ay+ +++++ W++++D  Vt++++ee ++++      ++aY+l+Y 
   Q: 577  ielmysdksmiQVPYRLHAVLVHEGQANAGHYWAYIFDHRESrWMKYNDIAVTKSSWEELVRDSFggyrnASAYCLMYI 655
           88888888888**************************966556***************99997779************6 PP
   
Organism Nomascus leucogenys
Protein Sequence
(Fasta)
MTVEQNVLQQ SAAQKHQQTF LNQLREITGI NDTQILQQAL KDSNGNLELA VAFLTAKNAK 60
TPQQEETTYY QTALPGNDRY ISVGSQADTN VIDLTGDDKD DLQRAIALSL AESNRAFRET 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Nle-069075|DUB,USP|Nomascus leucogenys
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCAGCCCGCA AGCCGCCAGC GAAGGAGCGC GCGAACGCGT GACGCCGCCC GACTGGCTCA 60
CGCTCTCCCG TGCCCCGGCG TCCTCCGCCC GCTCATGGCC CGGGCCGCCG CGGACGAGCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Nle-069075|DUB,USP|Nomascus leucogenys
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR003903--UIM_dom
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
PF02809--UIM
SMART

SM00726--UIM
Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1904293--P:negative regulation of ERAD pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001340 Ailuropoda melanoleuca 94.01 0.00e+00 1996.00
IUUC-Apl-004030 Anas platyrhynchos 83.07 0.00e+00 1823.00
IUUC-Aca-004753 Anolis carolinensis 65.10 0.00e+00 1006.00
IUUC-Ani-009503 Aspergillus nidulans 33.02 8.00e-11 63.20
IUUC-Ame-010624 Astyanax mexicanus 70.94 0.00e+00 1090.00
IUUC-Bta-013166 Bos taurus 96.39 0.00e+00 1989.00
IUUC-Cel-018346 Caenorhabditis elegans 28.61 4.00e-29 124.00
IUUC-Cja-019150 Callithrix jacchus 99.61 0.00e+00 1468.00
IUUC-Cfa-020649 Canis familiaris 97.05 0.00e+00 1460.00
IUUC-Cpo-021807 Cavia porcellus 93.65 0.00e+00 2075.00
IUUC-Csa-023388 Chlorocebus sabaeus 99.61 0.00e+00 1470.00
IUUC-Cho-024343 Choloepus hoffmanni 83.28 0.00e+00 983.00
IUUC-Cin-025302 Ciona intestinalis 37.33 7.00e-96 344.00
IUUC-Cgl-026575 Colletotrichum gloeosporioides 53.19 5.00e-10 60.50
IUUC-Dre-028016 Danio rerio 77.14 0.00e+00 1189.00
IUUC-Dno-029495 Dasypus novemcinctus 91.05 0.00e+00 1445.00
IUUC-Dor-030948 Dipodomys ordii 82.04 0.00e+00 1445.00
IUUC-Fca-035876 Felis catus 96.92 0.00e+00 2014.00
IUUC-Fal-036762 Ficedula albicollis 84.26 0.00e+00 1112.00
IUUC-Gmo-039490 Gadus morhua 72.07 0.00e+00 1543.00
IUUC-Gga-040817 Gallus gallus 85.09 0.00e+00 1347.00
IUUC-Gac-042473 Gasterosteus aculeatus 72.30 0.00e+00 1575.00
IUUC-Ggo-044939 Gorilla gorilla 94.94 0.00e+00 1976.00
IUUC-Hsa-046204 Homo sapiens 99.62 0.00e+00 2041.00
IUUC-Kpa-049349 Komagataella pastoris 28.12 3.00e-10 61.60
IUUC-Lch-049572 Latimeria chalumnae 79.40 0.00e+00 1219.00
IUUC-Loc-052070 Lepisosteus oculatus 76.40 0.00e+00 1223.00
IUUC-Lma-053078 Leptosphaeria maculans 30.56 4.00e-12 67.40
IUUC-Laf-054426 Loxodonta africana 96.90 0.00e+00 1852.00
IUUC-Mcc-055858 Macaca mulatta 99.74 0.00e+00 1500.00
IUUC-Mga-059808 Meleagris gallopavo 85.32 0.00e+00 1837.00
IUUC-Mmr-060987 Microcebus murinus 98.33 0.00e+00 1454.00
IUUC-Mmu-064245 Mus musculus 93.56 0.00e+00 2001.00
IUUC-Mpu-066304 Mustela putorius furo 96.61 0.00e+00 1429.00
IUUC-Mlu-067139 Myotis lucifugus 95.96 0.00e+00 2017.00
IUUC-Ont-072150 Oreochromis niloticus 74.70 0.00e+00 1202.00
IUUC-Oan-073054 Ornithorhynchus anatinus 79.93 0.00e+00 1700.00
IUUC-Ocu-074102 Oryctolagus cuniculus 94.55 0.00e+00 1453.00
IUUC-Ola-086529 Oryzias latipes 69.93 0.00e+00 1516.00
IUUC-Oga-088939 Otolemur garnettii 95.94 0.00e+00 2011.00
IUUC-Oar-090266 Ovis aries 97.52 0.00e+00 1435.00
IUUC-Ptr-090546 Pan troglodytes 99.43 0.00e+00 2039.00
IUUC-Pan-092311 Papio anubis 99.61 0.00e+00 1498.00
IUUC-Psi-093459 Pelodiscus sinensis 91.03 0.00e+00 1176.00
IUUC-Pfo-096726 Poecilia formosa 73.70 0.00e+00 1184.00
IUUC-Pab-097608 Pongo abelii 96.64 0.00e+00 1995.00
IUUC-Pca-100718 Procavia capensis 92.19 0.00e+00 1241.00
IUUC-Pva-103150 Pteropus vampyrus 92.35 0.00e+00 1479.00
IUUC-Rno-105727 Rattus norvegicus 94.22 0.00e+00 1969.00
IUUC-Sha-107051 Sarcophilus harrisii 89.33 0.00e+00 1869.00
IUUC-Sar-113097 Sorex araneus 86.57 0.00e+00 1834.00
IUUC-Ssc-115877 Sus scrofa 94.36 0.00e+00 1970.00
IUUC-Tgu-117473 Taeniopygia guttata 77.95 0.00e+00 1691.00
IUUC-Tru-118135 Takifugu rubripes 67.37 0.00e+00 1429.00
IUUC-Tsy-119471 Tarsius syrichta 89.99 0.00e+00 1811.00
IUUC-Tni-120139 Tetraodon nigroviridis 67.61 0.00e+00 1346.00
IUUC-Tbe-127549 Tupaia belangeri 90.58 0.00e+00 1887.00
IUUC-Ttr-128896 Tursiops truncatus 90.06 0.00e+00 1910.00
IUUC-Vpa-130500 Vicugna pacos 93.72 0.00e+00 1337.00
IUUC-Xtr-132896 Xenopus tropicalis 80.98 0.00e+00 1734.00
IUUC-Xma-133349 Xiphophorus maculatus 74.72 0.00e+00 1616.00
Created Date 25-Jun-2017

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