iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055180

Ensembl Protein ID

ENSMMUP00000006731.2

UniProt Accession

F7C4B0; H9FNB0; F7C4B0_MACMU

Genbank Protein ID

AFE76119.1

Protein Name

Abl interactor 1 isoform a

Genbank Nucleotide ID

JSUE03043097

Gene Name

ABI1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000005078.3	ENSMMUT00000007163.2	ENSMMUP00000006731.2
ENSMMUG00000005078.3	ENSMMUT00000007162.3	ENSMMUP00000006730.3
ENSMMUG00000005078.3	ENSMMUT00000007161.3	ENSMMUP00000006729.3
ENSMMUG00000005078.3	ENSMMUT00000007160.3	ENSMMUP00000006728.3
ENSMMUG00000005078.3	ENSMMUT00000072752.1	ENSMMUP00000044809.1
ENSMMUG00000005078.3	ENSMMUT00000060896.1	ENSMMUP00000055745.1
ENSMMUG00000005078.3	ENSMMUT00000043110.2	ENSMMUP00000036124.2
ENSMMUG00000005078.3	ENSMMUT00000043109.2	ENSMMUP00000036123.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.70e-14	52.2	449	503

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           ekv ++ydy+  +ddeL++ +G +++vi  +++d gW +g    +   GlfP n+ve +
   Q: 449  EKVVAIYDYTKDKDDELSFMEGAIIYVI--KKNDDGWYEG--VCNRVTGLFPGNYVESI 503
           789*************************..99********..79************987 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAELQMLLEE EIPSGKRALI ESYQNLTRVA DYCENNYIQA TDKRKALEET KAYTTQSLAS 60
VAYQINALAN NVLQLLDIQA SQLRRMESSI NHISQTVDIH KEKVARREIG ILTTNKNTSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGAAGACTCG CGAGAGAACG AGGTTCAGGC GGCTGCGCGA AGTGGGTGGA GGGAGACCCG 60
AGAGAGTGAG GAAGAACGGG AGGAGGTGCC GTCCCACAAT ACCAGGCGGG AGGGCGGGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028457--ABI
IPR028456--ABI1/ABI2
IPR012849--Abl-interactor_HHR_dom
IPR001452--SH3_domain
IPR000727--T_SNARE_dom

PROSITE

PS50002--SH3
PS50192--T_SNARE

Pfam

PF07815--Abi_HHR
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0030175--C:filopodium
GO:0030027--C:lamellipodium
GO:0043005--C:neuron projection
GO:0031209--C:SCAR complex
GO:0030296--F:protein tyrosine kinase activator activity
GO:0008154--P:actin polymerization or depolymerization
GO:0048813--P:dendrite morphogenesis
GO:0072673--P:lamellipodium morphogenesis
GO:0035855--P:megakaryocyte development
GO:0018108--P:peptidyl-tyrosine phosphorylation
GO:0001756--P:somitogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001375	Ailuropoda melanoleuca	97.64	0.00e+00	777.00
IUUC-Apl-003291	Anas platyrhynchos	95.09	0.00e+00	754.00
IUUC-Aca-004955	Anolis carolinensis	90.30	0.00e+00	665.00
IUUC-Ame-011140	Astyanax mexicanus	60.34	1.00e-141	496.00
IUUC-Bta-013104	Bos taurus	65.64	5.00e-154	537.00
IUUC-Cja-019099	Callithrix jacchus	99.80	0.00e+00	796.00
IUUC-Cfa-020201	Canis familiaris	99.21	0.00e+00	795.00
IUUC-Cpo-021955	Cavia porcellus	97.91	8.00e-129	453.00
IUUC-Csa-024155	Chlorocebus sabaeus	100.00	0.00e+00	792.00
IUUC-Cho-024588	Choloepus hoffmanni	97.08	4.00e-127	448.00
IUUC-Cin-025769	Ciona intestinalis	55.88	3.00e-66	246.00
IUUC-Csv-026114	Ciona savignyi	61.29	2.00e-66	246.00
IUUC-Dre-028665	Danio rerio	94.44	5.00e-128	451.00
IUUC-Dno-029586	Dasypus novemcinctus	94.69	0.00e+00	779.00
IUUC-Ete-032286	Echinops telfairi	96.26	0.00e+00	789.00
IUUC-Eca-033716	Equus caballus	99.15	0.00e+00	714.00
IUUC-Eeu-034628	Erinaceus europaeus	83.81	7.00e-122	430.00
IUUC-Fca-036186	Felis catus	97.44	0.00e+00	780.00
IUUC-Fal-037526	Ficedula albicollis	95.67	0.00e+00	770.00
IUUC-Gmo-039109	Gadus morhua	72.01	4.00e-177	614.00
IUUC-Gga-040990	Gallus gallus	96.46	0.00e+00	776.00
IUUC-Gac-042525	Gasterosteus aculeatus	76.89	0.00e+00	673.00
IUUC-Ggo-044789	Gorilla gorilla	99.21	0.00e+00	780.00
IUUC-Hsa-045845	Homo sapiens	100.00	0.00e+00	792.00
IUUC-Itr-048893	Ictidomys tridecemlineatus	99.57	8.00e-112	396.00
IUUC-Lch-050579	Latimeria chalumnae	86.85	2.00e-152	531.00
IUUC-Loc-052683	Lepisosteus oculatus	87.38	0.00e+00	713.00
IUUC-Laf-054032	Loxodonta africana	93.90	0.00e+00	771.00
IUUC-Mga-059287	Meleagris gallopavo	89.17	0.00e+00	679.00
IUUC-Mmr-061282	Microcebus murinus	99.80	0.00e+00	796.00
IUUC-Mdo-062996	Monodelphis domestica	93.50	0.00e+00	762.00
IUUC-Mmu-063875	Mus musculus	92.32	0.00e+00	724.00
IUUC-Mpu-065785	Mustela putorius furo	98.23	0.00e+00	787.00
IUUC-Mlu-068146	Myotis lucifugus	91.43	0.00e+00	704.00
IUUC-Nle-070077	Nomascus leucogenys	93.50	0.00e+00	758.00
IUUC-Opr-070618	Ochotona princeps	77.26	5.00e-101	361.00
IUUC-Ont-072203	Oreochromis niloticus	77.95	0.00e+00	638.00
IUUC-Oan-073650	Ornithorhynchus anatinus	92.32	0.00e+00	761.00
IUUC-Ocu-074682	Oryctolagus cuniculus	94.29	0.00e+00	778.00
IUUC-Opu-083893	Oryza punctata	21.98	1.30e+00	28.90
IUUC-Ola-086654	Oryzias latipes	71.29	3.00e-170	591.00
IUUC-Oga-088619	Otolemur garnettii	92.43	5.00e-170	590.00
IUUC-Oar-089983	Ovis aries	94.69	0.00e+00	779.00
IUUC-Ptr-091652	Pan troglodytes	99.61	0.00e+00	791.00
IUUC-Pan-091799	Papio anubis	94.69	0.00e+00	779.00
IUUC-Psi-093802	Pelodiscus sinensis	91.54	0.00e+00	745.00
IUUC-Pfo-097441	Poecilia formosa	79.77	0.00e+00	652.00
IUUC-Pab-098208	Pongo abelii	94.69	0.00e+00	779.00
IUUC-Pca-100439	Procavia capensis	61.70	9.00e-100	357.00
IUUC-Pva-102520	Pteropus vampyrus	98.82	0.00e+00	781.00
IUUC-Rno-106012	Rattus norvegicus	92.72	0.00e+00	726.00
IUUC-Sha-106615	Sarcophilus harrisii	88.41	0.00e+00	633.00
IUUC-Sar-113140	Sorex araneus	91.34	0.00e+00	711.00
IUUC-Ssc-115676	Sus scrofa	100.00	4.00e-77	280.00
IUUC-Tgu-117093	Taeniopygia guttata	95.33	0.00e+00	695.00
IUUC-Tru-117869	Takifugu rubripes	78.38	0.00e+00	635.00
IUUC-Tsy-119104	Tarsius syrichta	92.96	0.00e+00	640.00
IUUC-Tni-120686	Tetraodon nigroviridis	76.12	0.00e+00	654.00
IUUC-Tbe-127508	Tupaia belangeri	94.49	0.00e+00	722.00
IUUC-Ttr-129105	Tursiops truncatus	98.17	0.00e+00	744.00
IUUC-Vpa-130514	Vicugna pacos	97.87	0.00e+00	670.00
IUUC-Xtr-131805	Xenopus tropicalis	85.63	0.00e+00	723.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence