iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000019426.11	ENSDART00000144275.2	ENSDARP00000118025.2
ENSDARG00000019426.11	ENSDART00000087055.5	ENSDARP00000081489.4
ENSDARG00000019426.11	ENSDART00000163475.1	ENSDARP00000137053.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.20e-10	41.2	1670	1721

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvk..elegkrGlfP 55
             v++d++a n++eLt+++G +v+v+e  +   +W+           +Gl+P
   Q: 1670 TVVIHDFMAGNSNELTIRRGQTVEVLERLHDKPDWCLVRTtdRSPALEGLVP 1721
           679***********************9999999**97654223334567776 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MYLHCGAVED TDSLSSWWNG NVASLLDNHR WQYAQTGNTL IQLPGKALTP LLGFRRNEEM 60
KAMEVLPILK EKVAFLSGGR DKRGGPVLTF PSRTNHDRIR HEDLRRLIAY LAGIPSEDVC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCCGCCCC CTGCCGTCTC TCCGCTCCGC ACGGGAGAAC CGACCGCCGG CCGGCGCTGT 60
TAATGTGTGT TATAACCAAG ATGGAGGAGG TTTTGTGATG TTCCCCAGCA GCACTCAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase

Interpro

IPR001251--CRAL-TRIO_dom
IPR000219--DH-domain
IPR007110--Ig-like_dom
IPR013783--Ig-like_fold
IPR013098--Ig_I-set
IPR003599--Ig_sub
IPR003598--Ig_sub2
IPR011009--Kinase-like_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain
IPR018159--Spectrin/alpha-actinin
IPR002017--Spectrin_repeat
IPR028570--TRIO

PROSITE

PS50191--CRAL_TRIO
PS50010--DH_2
PS50835--IG_LIKE
PS50003--PH_DOMAIN
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF00650--CRAL_TRIO
PF07679--I-set
PF00069--Pkinase
PF00621--RhoGEF
PF00018--SH3_1
PF00435--Spectrin

SMART

SM00409--IG
SM00408--IGc2
SM00233--PH
SM00325--RhoGEF
SM00220--S_TKc
SM00516--SEC14
SM00326--SH3
SM00150--SPEC

Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

KEGG

dre:557667

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001797	Ailuropoda melanoleuca	81.79	0.00e+00	4908.00
IUUC-Apl-003498	Anas platyrhynchos	82.75	0.00e+00	4652.00
IUUC-Bta-013121	Bos taurus	81.43	0.00e+00	4856.00
IUUC-Cja-018919	Callithrix jacchus	88.89	0.00e+00	3999.00
IUUC-Cfa-020547	Canis familiaris	81.32	0.00e+00	4858.00
IUUC-Cpo-022301	Cavia porcellus	82.29	0.00e+00	4910.00
IUUC-Csa-023889	Chlorocebus sabaeus	88.89	0.00e+00	3997.00
IUUC-Dno-028888	Dasypus novemcinctus	81.51	0.00e+00	4871.00
IUUC-Dor-030992	Dipodomys ordii	82.18	0.00e+00	3617.00
IUUC-Ete-033167	Echinops telfairi	83.17	0.00e+00	1533.00
IUUC-Eca-033685	Equus caballus	88.56	0.00e+00	3962.00
IUUC-Fca-035647	Felis catus	80.76	0.00e+00	4826.00
IUUC-Fal-036845	Ficedula albicollis	89.11	0.00e+00	4007.00
IUUC-Gga-040959	Gallus gallus	82.35	0.00e+00	4978.00
IUUC-Gac-041349	Gasterosteus aculeatus	90.52	0.00e+00	3988.00
IUUC-Ggo-045170	Gorilla gorilla	88.87	0.00e+00	3974.00
IUUC-Hsa-046059	Homo sapiens	88.84	0.00e+00	4000.00
IUUC-Lch-050010	Latimeria chalumnae	80.44	0.00e+00	4806.00
IUUC-Loc-052783	Lepisosteus oculatus	85.29	0.00e+00	5078.00
IUUC-Laf-053884	Loxodonta africana	88.76	0.00e+00	3976.00
IUUC-Mcc-055804	Macaca mulatta	88.56	0.00e+00	3982.00
IUUC-Mga-060008	Meleagris gallopavo	81.68	0.00e+00	4928.00
IUUC-Mmr-061081	Microcebus murinus	82.00	0.00e+00	4896.00
IUUC-Mdo-062888	Monodelphis domestica	90.20	0.00e+00	3715.00
IUUC-Mmu-063327	Mus musculus	81.97	0.00e+00	4843.00
IUUC-Mpu-066905	Mustela putorius furo	88.98	0.00e+00	4000.00
IUUC-Mlu-068215	Myotis lucifugus	85.98	0.00e+00	3923.00
IUUC-Nle-069414	Nomascus leucogenys	86.79	0.00e+00	3859.00
IUUC-Opr-070819	Ochotona princeps	84.46	0.00e+00	3840.00
IUUC-Ont-072678	Oreochromis niloticus	92.68	0.00e+00	4086.00
IUUC-Oan-072974	Ornithorhynchus anatinus	88.85	0.00e+00	4004.00
IUUC-Ocu-074919	Oryctolagus cuniculus	82.14	0.00e+00	4895.00
IUUC-Oga-088068	Otolemur garnettii	82.35	0.00e+00	4923.00
IUUC-Oar-090050	Ovis aries	85.71	0.00e+00	3856.00
IUUC-Ptr-090841	Pan troglodytes	88.88	0.00e+00	4000.00
IUUC-Psi-093088	Pelodiscus sinensis	81.85	0.00e+00	4923.00
IUUC-Pfo-097201	Poecilia formosa	84.48	0.00e+00	3734.00
IUUC-Pab-098130	Pongo abelii	88.88	0.00e+00	3994.00
IUUC-Pca-100839	Procavia capensis	77.58	0.00e+00	3305.00
IUUC-Pva-102115	Pteropus vampyrus	88.79	0.00e+00	2723.00
IUUC-Rno-105207	Rattus norvegicus	82.00	0.00e+00	4838.00
IUUC-Sha-107011	Sarcophilus harrisii	78.99	0.00e+00	3803.00
IUUC-Tgu-116970	Taeniopygia guttata	81.97	0.00e+00	4904.00
IUUC-Tru-117758	Takifugu rubripes	91.72	0.00e+00	4066.00
IUUC-Ttr-128857	Tursiops truncatus	80.94	0.00e+00	3616.00
IUUC-Xtr-131909	Xenopus tropicalis	79.13	0.00e+00	4771.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence