iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062575

UUCD1 version

UUC-MoD-00121

Ensembl Protein ID

ENSMODP00000005616.2

UniProt Accession

F6R5D3; F6R5D3_MONDO

Protein Name

Uncharacterized protein

Gene Name

UBE3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000004553.2	ENSMODT00000005735.2	ENSMODP00000005616.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.30e-112	376.7	711	1076

Active Site

Position(s)	Description	Evidence
1044	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           ++++k +++v+fv+     E+g+d++Gv++efl++++k++++p l+lf+++++d++ l+p+p+s++++ ++l+lFef+G++lgka++
   Q: 711  QNAMKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDER-LYPSPTSYIHE-NYLQLFEFVGKMLGKAVY 795
           67899*******************************************99987665.59*******76.****************** PP
   S: 84   dgrlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           +g ++d+p++++f+++llg+       s+++l+++d+e+yk+l++ik++ + d+++lgl+l++  +e+++g+  ++eL+pgG++ipV
   Q: 796  EGIVVDVPFASFFLSQLLGHhhsifYSSVDELPSLDAEFYKNLTSIKRY-DGDVSDLGLTLSY--DEDVMGQLVCHELVPGGKTIPV 879
           ********************777777999********************.6799998777776..5999****************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwe 251
           tneNk +Y++l++++r++++ik+q++++ +Gf+++i+ e++++F++ el+ li+G+ +eid+edlkk+t y gg++ ++++i+w+w+
   Q: 880  TNENKISYIHLMAHFRMHTQIKSQTASLISGFRSIIKWEWIRMFSTPELQRLISGDnAEIDLEDLKKHTVYYGGFHGSHRVIIWLWD 966
           ********************************************************9****************************** PP
   S: 252  vl.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeY 313
           +l ++f+ eer++fL+FvT++sr Pl Gfa+lk                        + +f+irk++   rlP+s+TCfn+LkLP+Y
   Q: 967  ILaNDFTPEERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKKEPGGRLPTSSTCFNLLKLPNY 1053
           **99*************************************************************9999****************** PP
   S: 314  sskeilkekLlyAieetkgFels 336
           s+k+il+ekL+yAi++++gFels
   Q: 1054 SKKSILREKLRYAISMNTGFELS 1076
           ********************985 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MVQFAKMFGT SQSSRAQFLD KARQAREERR GQKEKERAAV QIQAVVRSFL CRCRLQNDIR 60
KEIDDFFDET DPGPSKRSAL CLFKIGRKLL FIFQASEDEL RFGMLCRCIL DSMNENDPKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAAAGAAA AGAAATAACT CGGACCAGGC TCCCTTCCTG CTTTGTTGCC CTCACTATGA 60
GCTGTCAAGA GAGGACATGC CTTTTGTGTG CATTGTGATG GGTAACTGAA TTTACGAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	39.08	8.00e-104	372.00
IUUC-Aml-002107	Ailuropoda melanoleuca	84.13	0.00e+00	1830.00
IUUC-Atr-003017	Amborella trichopoda	38.30	4.00e-108	386.00
IUUC-Apl-003328	Anas platyrhynchos	85.37	0.00e+00	1788.00
IUUC-Aly-005794	Arabidopsis lyrata	38.75	4.00e-107	382.00
IUUC-Ath-007269	Arabidopsis thaliana	39.46	4.00e-110	392.00
IUUC-Bta-013547	Bos taurus	83.85	0.00e+00	1850.00
IUUC-Bdi-014502	Brachypodium distachyon	38.61	5.00e-107	382.00
IUUC-Bol-015093	Brassica oleracea	40.18	1.00e-111	397.00
IUUC-Bra-016722	Brassica rapa	40.18	2.00e-112	400.00
IUUC-Cel-018447	Caenorhabditis elegans	38.44	0.00e+00	689.00
IUUC-Cja-019855	Callithrix jacchus	83.75	0.00e+00	1819.00
IUUC-Cfa-020066	Canis familiaris	83.58	0.00e+00	1804.00
IUUC-Cpo-021504	Cavia porcellus	83.19	0.00e+00	1841.00
IUUC-Csa-023579	Chlorocebus sabaeus	83.94	0.00e+00	1826.00
IUUC-Cho-024430	Choloepus hoffmanni	72.63	0.00e+00	1307.00
IUUC-Cin-025750	Ciona intestinalis	46.17	0.00e+00	935.00
IUUC-Csv-026016	Ciona savignyi	47.02	0.00e+00	988.00
IUUC-Dre-028271	Danio rerio	80.21	0.00e+00	1730.00
IUUC-Dno-029054	Dasypus novemcinctus	84.22	0.00e+00	1831.00
IUUC-Dor-030938	Dipodomys ordii	88.28	0.00e+00	1123.00
IUUC-Dme-031602	Drosophila melanogaster	46.49	0.00e+00	913.00
IUUC-Ete-033041	Echinops telfairi	68.58	0.00e+00	1224.00
IUUC-Eca-034411	Equus caballus	84.22	0.00e+00	1810.00
IUUC-Eeu-035201	Erinaceus europaeus	81.90	0.00e+00	776.00
IUUC-Fca-036594	Felis catus	83.01	0.00e+00	1793.00
IUUC-Fal-037317	Ficedula albicollis	82.15	0.00e+00	1810.00
IUUC-Gmo-039412	Gadus morhua	76.85	0.00e+00	1720.00
IUUC-Gga-040149	Gallus gallus	85.43	0.00e+00	1831.00
IUUC-Gac-042088	Gasterosteus aculeatus	79.80	0.00e+00	1793.00
IUUC-Gma-043839	Glycine max	39.79	8.00e-110	391.00
IUUC-Ggo-045279	Gorilla gorilla	84.03	0.00e+00	1827.00
IUUC-Hsa-045660	Homo sapiens	84.03	0.00e+00	1827.00
IUUC-Hvu-047102	Hordeum vulgare	38.90	3.00e-103	370.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	97.12	0.00e+00	843.00
IUUC-Lch-050664	Latimeria chalumnae	81.53	0.00e+00	1796.00
IUUC-Lpe-050755	Leersia perrieri	37.12	7.00e-96	345.00
IUUC-Loc-052791	Lepisosteus oculatus	81.77	0.00e+00	1752.00
IUUC-Laf-053902	Loxodonta africana	84.69	0.00e+00	1842.00
IUUC-Mcc-054730	Macaca mulatta	83.94	0.00e+00	1826.00
IUUC-Meu-056527	Macropus eugenii	87.50	0.00e+00	1829.00
IUUC-Mtr-057671	Medicago truncatula	39.43	3.00e-110	393.00
IUUC-Mga-059260	Meleagris gallopavo	85.18	0.00e+00	1831.00
IUUC-Mmr-060804	Microcebus murinus	83.10	0.00e+00	1763.00
IUUC-Mmu-063636	Mus musculus	82.54	0.00e+00	1759.00
IUUC-Mac-064989	Musa acuminata	38.30	2.00e-104	374.00
IUUC-Mpu-066677	Mustela putorius furo	82.64	0.00e+00	1704.00
IUUC-Mlu-067952	Myotis lucifugus	84.31	0.00e+00	1774.00
IUUC-Nle-069153	Nomascus leucogenys	84.13	0.00e+00	1826.00
IUUC-Opr-070554	Ochotona princeps	84.78	0.00e+00	1689.00
IUUC-Ont-071372	Oreochromis niloticus	80.49	0.00e+00	1758.00
IUUC-Oan-073327	Ornithorhynchus anatinus	68.57	0.00e+00	707.00
IUUC-Ocu-074183	Oryctolagus cuniculus	82.91	0.00e+00	1798.00
IUUC-Oba-075213	Oryza barthii	38.92	7.00e-104	372.00
IUUC-Obr-076320	Oryza brachyantha	38.74	1.00e-106	380.00
IUUC-Ogl-077093	Oryza glaberrima	39.09	2.00e-106	380.00
IUUC-Ogu-078947	Oryza glumaepatula	36.59	1.00e-108	387.00
IUUC-Oin-080058	Oryza indica	39.09	2.00e-106	380.00
IUUC-Olo-080742	Oryza longistaminata	35.38	4.00e-105	376.00
IUUC-Ome-081741	Oryza meridionalis	35.45	2.00e-99	357.00
IUUC-Oni-082385	Oryza nivara	36.59	1.00e-108	387.00
IUUC-Opu-083529	Oryza punctata	35.81	1.00e-106	381.00
IUUC-Oru-085128	Oryza rufipogon	36.69	5.00e-93	335.00
IUUC-Osa-085557	Oryza sativa	39.09	4.00e-106	379.00
IUUC-Ola-087337	Oryzias latipes	80.30	0.00e+00	1711.00
IUUC-Oga-088342	Otolemur garnettii	83.49	0.00e+00	1741.00
IUUC-Oar-090234	Ovis aries	83.21	0.00e+00	1818.00
IUUC-Ptr-091661	Pan troglodytes	84.03	0.00e+00	1826.00
IUUC-Pan-092728	Papio anubis	83.68	0.00e+00	1820.00
IUUC-Psi-093251	Pelodiscus sinensis	84.19	0.00e+00	1702.00
IUUC-Pma-094195	Petromyzon marinus	69.75	0.00e+00	1443.00
IUUC-Ppa-095544	Physcomitrella patens	38.36	2.00e-110	394.00
IUUC-Pfo-097472	Poecilia formosa	80.67	0.00e+00	1776.00
IUUC-Pab-098570	Pongo abelii	84.22	0.00e+00	1827.00
IUUC-Pca-100110	Procavia capensis	73.95	0.00e+00	1547.00
IUUC-Ppe-101281	Prunus persica	38.30	2.00e-104	374.00
IUUC-Pva-102887	Pteropus vampyrus	79.76	0.00e+00	1696.00
IUUC-Rno-106028	Rattus norvegicus	79.29	0.00e+00	1644.00
IUUC-Sha-107331	Sarcophilus harrisii	93.38	0.00e+00	1958.00
IUUC-Smo-109488	Selaginella moellendorffii	37.14	9.00e-105	375.00
IUUC-Sit-109811	Setaria italica	35.65	4.00e-107	383.00
IUUC-Sar-113287	Sorex araneus	67.44	2.00e-163	569.00
IUUC-Sbi-114433	Sorghum bicolor	39.22	1.00e-107	384.00
IUUC-Ssc-116103	Sus scrofa	84.59	0.00e+00	1819.00
IUUC-Tgu-117275	Taeniopygia guttata	84.87	0.00e+00	1813.00
IUUC-Tru-118681	Takifugu rubripes	79.27	0.00e+00	1790.00
IUUC-Tsy-118985	Tarsius syrichta	71.87	0.00e+00	823.00
IUUC-Tni-120850	Tetraodon nigroviridis	91.48	0.00e+00	773.00
IUUC-Tca-121770	Theobroma cacao	39.18	1.00e-109	391.00
IUUC-Tae-125466	Triticum aestivum	36.41	6.00e-106	379.00
IUUC-Tur-126086	Triticum urartu	39.32	3.00e-103	370.00
IUUC-Tbe-127461	Tupaia belangeri	79.46	0.00e+00	1652.00
IUUC-Ttr-129269	Tursiops truncatus	83.29	0.00e+00	1788.00
IUUC-Vpa-130523	Vicugna pacos	73.18	2.00e-111	397.00
IUUC-Vvi-131524	Vitis vinifera	38.50	4.00e-107	382.00
IUUC-Xtr-132146	Xenopus tropicalis	83.49	0.00e+00	1826.00
IUUC-Xma-133526	Xiphophorus maculatus	80.39	0.00e+00	1769.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence