iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019317

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACFV01046985

Gene Name

TRIM62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000001177.2	ENSCJAT00000002145.1	ENSCJAP00000002027.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.30e-08	34.5	11	54
E3 activity/RING/U-box	1.30e-06	29.3	6	75

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl+ ++d p++l+C H f++ C+ ++w+ +   ++++  CP Cr
   Q: 11   CSICLSIYQD-PVSLGCEHYFCRRCItEHWVRQE--AQGARDCPECR 54
           **********.*******************5555..**********8 PP

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwl....asggktcPvtrqplteedlvPnltlrrliqaw 68
            +e+lC+I l + +dPv l + + + r++I ++     a+g + cP +r++++e  l P+l l ++++++
   Q: 6    KDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWvrqeAQGARDCPECRRTFAEPALAPSLKLANIVERY 75
           689***************************9888455444444*******************99999887 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MACSLKDELL CSICLSIYQD PVSLGCEHYF CRRCITEHWV RQEAQGARDC PECRRTFAEP 60
ALAPSLKLAN IVERYSAFPL DAILNARRAA RPCQAHDKVK LFCLTDRALL CFFCDEPALH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTGCA GCCTCAAGGA CGAGCTGCTG TGCTCCATCT GCCTGAGCAT CTACCAGGAT 60
CCGGTGAGCC TGGGGTGCGA GCACTACTTC TGCCGCCGCT GCATCACCGA GCACTGGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0010719--P:negative regulation of epithelial to mesenchymal transition
GO:0032897--P:negative regulation of viral transcription
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0046596--P:regulation of viral entry into host cell
GO:1902186--P:regulation of viral release from host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002199	Ailuropoda melanoleuca	93.47	0.00e+00	867.00
IUUC-Apl-003767	Anas platyrhynchos	81.94	0.00e+00	717.00
IUUC-Aca-004412	Anolis carolinensis	78.87	0.00e+00	739.00
IUUC-Ame-010927	Astyanax mexicanus	77.26	0.00e+00	768.00
IUUC-Bta-012927	Bos taurus	93.26	0.00e+00	865.00
IUUC-Cfa-020292	Canis familiaris	90.59	1.00e-176	612.00
IUUC-Cpo-022274	Cavia porcellus	90.62	9.00e-178	615.00
IUUC-Csa-023042	Chlorocebus sabaeus	93.47	0.00e+00	867.00
IUUC-Dre-028493	Danio rerio	76.00	0.00e+00	760.00
IUUC-Dno-030029	Dasypus novemcinctus	88.84	0.00e+00	807.00
IUUC-Dor-031051	Dipodomys ordii	90.33	0.00e+00	817.00
IUUC-Ete-032752	Echinops telfairi	98.21	2.00e-85	309.00
IUUC-Eca-033898	Equus caballus	73.56	0.00e+00	738.00
IUUC-Eeu-034659	Erinaceus europaeus	100.00	1.00e-84	305.00
IUUC-Fca-035492	Felis catus	84.70	0.00e+00	799.00
IUUC-Fal-036867	Ficedula albicollis	82.33	0.00e+00	772.00
IUUC-Gmo-038916	Gadus morhua	76.63	0.00e+00	739.00
IUUC-Gga-040360	Gallus gallus	84.63	0.00e+00	796.00
IUUC-Gac-041871	Gasterosteus aculeatus	77.26	0.00e+00	771.00
IUUC-Ggo-044411	Gorilla gorilla	86.58	0.00e+00	793.00
IUUC-Hsa-047025	Homo sapiens	92.84	0.00e+00	895.00
IUUC-Itr-047905	Ictidomys tridecemlineatus	93.47	0.00e+00	867.00
IUUC-Lch-050624	Latimeria chalumnae	80.58	7.00e-69	251.00
IUUC-Loc-052114	Lepisosteus oculatus	78.74	0.00e+00	781.00
IUUC-Laf-054359	Loxodonta africana	85.94	6.00e-169	586.00
IUUC-Mcc-055563	Macaca mulatta	93.47	0.00e+00	867.00
IUUC-Meu-056027	Macropus eugenii	70.11	0.00e+00	643.00
IUUC-Mga-060146	Meleagris gallopavo	84.30	3.00e-75	273.00
IUUC-Mmr-060822	Microcebus murinus	93.26	0.00e+00	864.00
IUUC-Mdo-062117	Monodelphis domestica	77.10	2.00e-168	585.00
IUUC-Mmu-064086	Mus musculus	93.26	0.00e+00	867.00
IUUC-Mpu-066378	Mustela putorius furo	93.47	0.00e+00	867.00
IUUC-Mlu-067155	Myotis lucifugus	92.34	0.00e+00	880.00
IUUC-Nle-069464	Nomascus leucogenys	93.05	0.00e+00	863.00
IUUC-Opr-071058	Ochotona princeps	84.62	5.00e-107	381.00
IUUC-Ont-071253	Oreochromis niloticus	68.62	0.00e+00	646.00
IUUC-Oan-073198	Ornithorhynchus anatinus	95.29	3.00e-84	304.00
IUUC-Ola-086794	Oryzias latipes	77.47	0.00e+00	764.00
IUUC-Oga-088889	Otolemur garnettii	93.05	0.00e+00	865.00
IUUC-Oar-089203	Ovis aries	88.76	0.00e+00	754.00
IUUC-Ptr-090795	Pan troglodytes	93.05	0.00e+00	896.00
IUUC-Pfo-096942	Poecilia formosa	76.84	0.00e+00	759.00
IUUC-Pab-097936	Pongo abelii	84.87	0.00e+00	634.00
IUUC-Pca-100397	Procavia capensis	92.00	0.00e+00	857.00
IUUC-Ppe-101916	Prunus persica	30.97	3.00e-10	61.20
IUUC-Pva-102293	Pteropus vampyrus	90.27	5.00e-173	600.00
IUUC-Rno-105551	Rattus norvegicus	93.05	0.00e+00	863.00
IUUC-Sre-115193	Sporisorium reilianum	45.83	3.00e-07	50.80
IUUC-Ssc-115983	Sus scrofa	93.47	0.00e+00	867.00
IUUC-Tgu-117279	Taeniopygia guttata	68.82	8.00e-165	573.00
IUUC-Tru-118238	Takifugu rubripes	77.05	0.00e+00	765.00
IUUC-Tni-119788	Tetraodon nigroviridis	55.30	3.00e-133	468.00
IUUC-Uma-129518	Ustilago maydis	45.83	3.00e-07	50.80
IUUC-Xtr-132768	Xenopus tropicalis	69.42	0.00e+00	647.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence