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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Ath-007535
UUCD1 version UUC-ArT-01162
Ensembl Protein ID AT3G42830.1
UniProt Accession Q9M2B0; Q1PEJ6; RBX1B_ARATH
Genbank Protein ID CAB87200.1; AEE77754.1; ABE65984.1
Protein Name RING-box protein 1b; At-Rbx1; 2; RBX1-1; RBX1b-At
Genbank Nucleotide ID AL138639; CP002686; DQ446722
Gene Name RBX1B; At3g42830; T21C14.50
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT3G42830 AT3G42830.1 AT3G42830.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
Protein Expression/Proteomics
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 4.70e-08 34.3 49 103
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplv..................lpCgHvfhadClqkwpglknssskefrCPl 44
           CaiC+++++d +++                  + C+H+fh++C+ +w       ++++ CPl
   Q: 49   CAICRNHIMD-LCIeclanqasatseectvawGVCNHAFHFHCISRW------LKTRQVCPL 103
           ********66.55333344444433333333488*************......********5 PP
   
Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description


     Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. The SCF complex plays a crucial role in regulating response to auxin and is essential for growth and development. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme, to the complex and brings it into close proximity to the substrate (By similarity).
 Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. The SCF complex plays a crucial role in regulating response to auxin and is essential for growth and development. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme, to the complex and brings it into close proximity to the substrate (By similarity).
Protein Sequence
(Fasta)
MASLNSDVIM GESSSISVPS SSSKNSKRFE LKKWSAVALW AWDIVVDNCA ICRNHIMDLC 60
IECLANQASA TSEECTVAWG VCNHAFHFHC ISRWLKTRQV CPLDVCEWEF QKYGH 115
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Protein Fasta Sequence


>IUUC-Ath-007535|E3,RING|Arabidopsis thaliana
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Nucleotide Sequence
(Fasta)
ATGGCTTCTC TCAACTCCGA CGTTATCATG GGTGAATCCT CCTCCATCTC CGTACCTTCA 60
TCTTCGTCCA AGAACTCGAA ACGATTTGAA TTAAAGAAGT GGAGTGCTGT CGCTCTCTGG 120
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Nucleotide Fasta Sequence


>IUUC-Ath-007535|E3,RING|Arabidopsis thaliana
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Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR024766--Znf_RING_H2
PROSITE

PS50089--ZF_RING_2
Pfam

PF12678--zf-rbx1
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination
KEGG ath:AT3G42830
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001798 Ailuropoda melanoleuca 94.38 6.00e-47 177.00
IUUC-Apl-003762 Anas platyrhynchos 94.87 3.00e-39 151.00
IUUC-Aca-005328 Anolis carolinensis 94.38 5.00e-47 177.00
IUUC-Ago-007991 Ashbya gossypii 62.50 8.00e-33 130.00
IUUC-Acl-008332 Aspergillus clavatus 87.50 7.00e-44 167.00
IUUC-Afl-008537 Aspergillus flavus 88.37 6.00e-43 164.00
IUUC-Afu-008985 Aspergillus fumigatus 86.52 5.00e-44 168.00
IUUC-Ani-009342 Aspergillus nidulans 87.50 4.00e-44 168.00
IUUC-Ang-009778 Aspergillus niger 88.37 6.00e-43 164.00
IUUC-Aor-009918 Aspergillus oryzae 88.37 6.00e-43 164.00
IUUC-Ame-010814 Astyanax mexicanus 94.64 6.00e-27 110.00
IUUC-Bgr-012224 Blumeria graminis 90.91 7.00e-46 174.00
IUUC-Bta-012426 Bos taurus 94.38 5.00e-47 177.00
IUUC-Bci-013839 Botrytis cinerea 90.91 9.00e-45 171.00
IUUC-Bdi-014575 Brachypodium distachyon 94.38 5.00e-47 178.00
IUUC-Cel-018195 Caenorhabditis elegans 87.64 6.00e-44 167.00
IUUC-Cja-018788 Callithrix jacchus 94.19 1.00e-44 170.00
IUUC-Cfa-020188 Canis familiaris 50.00 4.00e-21 92.00
IUUC-Cpo-021365 Cavia porcellus 94.38 5.00e-47 177.00
IUUC-Cre-022904 Chlamydomonas reinhardtii 54.02 3.00e-23 99.80
IUUC-Csa-024198 Chlorocebus sabaeus 94.38 5.00e-47 177.00
IUUC-Cho-024344 Choloepus hoffmanni 94.55 8.00e-27 110.00
IUUC-Cin-025449 Ciona intestinalis 92.13 8.00e-46 174.00
IUUC-Csv-026356 Ciona savignyi 50.67 1.00e-18 83.20
IUUC-Cgl-026522 Colletotrichum gloeosporioides 89.89 2.00e-45 172.00
IUUC-Cne-027067 Cryptococcus neoformans 76.71 6.00e-32 128.00
IUUC-Cme-027268 Cyanidioschyzon merolae 64.77 2.00e-32 129.00
IUUC-Dre-027434 Danio rerio 94.38 5.00e-47 177.00
IUUC-Dno-029252 Dasypus novemcinctus 93.02 6.00e-44 168.00
IUUC-Dor-030861 Dipodomys ordii 67.06 3.00e-28 115.00
IUUC-Dse-031355 Dothistroma septosporum 87.64 2.00e-44 169.00
IUUC-Dme-031585 Drosophila melanogaster 93.26 2.00e-46 176.00
IUUC-Ete-032747 Echinops telfairi 47.19 4.00e-14 68.90
IUUC-Eca-033758 Equus caballus 94.38 5.00e-47 177.00
IUUC-Fca-035586 Felis catus 94.38 5.00e-47 177.00
IUUC-Fal-037097 Ficedula albicollis 93.83 4.00e-41 157.00
IUUC-Fox-037881 Fusarium oxysporum 90.12 5.00e-40 154.00
IUUC-Fso-038373 Fusarium solani 87.64 3.00e-44 169.00
IUUC-Gmo-039457 Gadus morhua 94.12 5.00e-44 167.00
IUUC-Ggr-039970 Gaeumannomyces graminis 89.66 2.00e-43 166.00
IUUC-Gga-040328 Gallus gallus 94.38 5.00e-47 177.00
IUUC-Gac-041578 Gasterosteus aculeatus 94.38 5.00e-47 177.00
IUUC-Ggo-045249 Gorilla gorilla 94.55 1.00e-27 113.00
IUUC-Hsa-046279 Homo sapiens 94.38 5.00e-47 177.00
IUUC-Hvu-047597 Hordeum vulgare 94.38 8.00e-47 177.00
IUUC-Itr-048174 Ictidomys tridecemlineatus 94.38 5.00e-47 177.00
IUUC-Kpa-049330 Komagataella pastoris 65.17 4.00e-34 135.00
IUUC-Lch-049667 Latimeria chalumnae 94.38 5.00e-47 178.00
IUUC-Loc-052481 Lepisosteus oculatus 50.00 3.00e-21 92.80
IUUC-Lma-053052 Leptosphaeria maculans 92.05 5.00e-45 171.00
IUUC-Laf-053827 Loxodonta africana 93.10 6.00e-45 171.00
IUUC-Mcc-055208 Macaca mulatta 94.38 5.00e-47 177.00
IUUC-Meu-056143 Macropus eugenii 95.12 2.00e-42 162.00
IUUC-Mor-057158 Magnaporthe oryzae 90.80 5.00e-44 168.00
IUUC-Mpo-057409 Magnaporthe poae 89.66 2.00e-43 166.00
IUUC-Mla-059071 Melampsora laricipopulina 75.96 3.00e-41 159.00
IUUC-Mga-059797 Meleagris gallopavo 94.38 5.00e-47 177.00
IUUC-Mvi-060401 Microbotryum violaceum 86.52 7.00e-44 168.00
IUUC-Mmr-061077 Microcebus murinus 94.38 5.00e-47 177.00
IUUC-Mdo-062218 Monodelphis domestica 94.38 5.00e-47 177.00
IUUC-Mmu-064224 Mus musculus 94.38 5.00e-47 177.00
IUUC-Mac-064505 Musa acuminata 94.32 4.00e-46 174.00
IUUC-Mpu-066572 Mustela putorius furo 94.38 5.00e-47 177.00
IUUC-Mlu-067821 Myotis lucifugus 94.38 5.00e-47 177.00
IUUC-Nfi-068412 Neosartorya fischeri 87.50 7.00e-44 167.00
IUUC-Nle-069309 Nomascus leucogenys 94.38 5.00e-47 177.00
IUUC-Opr-070307 Ochotona princeps 94.38 5.00e-47 177.00
IUUC-Ont-071677 Oreochromis niloticus 94.38 5.00e-47 178.00
IUUC-Oan-072926 Ornithorhynchus anatinus 95.00 8.00e-41 157.00
IUUC-Oba-075405 Oryza barthii 94.38 6.00e-47 178.00
IUUC-Obr-076843 Oryza brachyantha 94.38 2.00e-47 180.00
IUUC-Ogl-077608 Oryza glaberrima 94.38 6.00e-47 178.00
IUUC-Ogu-078316 Oryza glumaepatula 94.38 6.00e-47 178.00
IUUC-Ome-081246 Oryza meridionalis 93.18 4.00e-46 175.00
IUUC-Oni-082052 Oryza nivara 94.38 6.00e-47 178.00
IUUC-Opu-084035 Oryza punctata 93.26 3.00e-47 179.00
IUUC-Oru-084941 Oryza rufipogon 94.38 6.00e-47 178.00
IUUC-Osa-085800 Oryza sativa 94.38 6.00e-47 178.00
IUUC-Ola-087352 Oryzias latipes 94.38 5.00e-47 178.00
IUUC-Olu-087676 Ostreococcus lucimarinus 53.49 4.00e-24 102.00
IUUC-Oga-088880 Otolemur garnettii 94.38 5.00e-47 177.00
IUUC-Oar-089286 Ovis aries 94.38 7.00e-47 177.00
IUUC-Ptr-091402 Pan troglodytes 94.38 5.00e-47 177.00
IUUC-Pan-091687 Papio anubis 93.26 4.00e-46 175.00
IUUC-Psi-093640 Pelodiscus sinensis 94.38 4.00e-47 178.00
IUUC-Pma-094723 Petromyzon marinus 93.98 1.00e-42 162.00
IUUC-Pno-094822 Phaeosphaeria nodorum 91.01 2.00e-45 173.00
IUUC-Pfo-096055 Poecilia formosa 94.38 5.00e-47 178.00
IUUC-Pab-098577 Pongo abelii 94.38 5.00e-47 177.00
IUUC-Pca-100719 Procavia capensis 94.38 5.00e-47 177.00
IUUC-Pva-102885 Pteropus vampyrus 65.17 5.00e-28 114.00
IUUC-Pgr-103470 Puccinia graminis 87.64 5.00e-44 168.00
IUUC-Ptt-103909 Puccinia triticina 87.72 2.00e-26 110.00
IUUC-Pte-104144 Pyrenophora teres 89.77 4.00e-42 162.00
IUUC-Pyt-104533 Pyrenophora triticirepentis 92.05 3.00e-45 172.00
IUUC-Rno-105912 Rattus norvegicus 94.38 5.00e-47 177.00
IUUC-Sce-106407 Saccharomyces cerevisiae 62.92 3.00e-32 129.00
IUUC-Sha-107549 Sarcophilus harrisii 94.38 5.00e-47 177.00
IUUC-Sja-108003 Schizosaccharomyces japonicus 85.39 2.00e-43 166.00
IUUC-Spo-108091 Schizosaccharomyces pombe 82.02 2.00e-41 159.00
IUUC-Ssl-108634 Sclerotinia sclerotiorum 90.91 7.00e-45 171.00
IUUC-Smo-109406 Selaginella moellendorffii 94.19 5.00e-45 171.00
IUUC-Sit-110419 Setaria italica 92.13 5.00e-46 174.00
IUUC-Stu-112567 Solanum tuberosum 93.26 3.00e-47 179.00
IUUC-Sar-113409 Sorex araneus 65.17 6.00e-28 114.00
IUUC-Sbi-113799 Sorghum bicolor 94.38 4.00e-47 178.00
IUUC-Sre-115142 Sporisorium reilianum 84.27 2.00e-42 162.00
IUUC-Tgu-116923 Taeniopygia guttata 93.67 1.00e-39 152.00
IUUC-Tru-117710 Takifugu rubripes 92.13 3.00e-46 176.00
IUUC-Tsy-119251 Tarsius syrichta 50.00 4.00e-21 92.00
IUUC-Tni-119934 Tetraodon nigroviridis 94.38 2.00e-47 180.00
IUUC-Tre-122212 Trichoderma reesei 90.12 2.00e-40 156.00
IUUC-Tvi-122357 Trichoderma virens 87.64 3.00e-44 169.00
IUUC-Tae-125834 Triticum aestivum 94.38 4.00e-47 178.00
IUUC-Tur-126093 Triticum urartu 94.38 1.00e-46 177.00
IUUC-Tme-126940 Tuber melanosporum 88.51 7.00e-44 167.00
IUUC-Tbe-127918 Tupaia belangeri 95.12 2.00e-42 162.00
IUUC-Ttr-128306 Tursiops truncatus 95.12 2.00e-42 162.00
IUUC-Uma-129482 Ustilago maydis 79.78 2.00e-40 156.00
IUUC-Vda-129917 Verticillium dahliae 91.01 5.00e-46 175.00
IUUC-Vpa-130142 Vicugna pacos 90.59 8.00e-41 157.00
IUUC-Xtr-132382 Xenopus tropicalis 50.00 8.00e-21 90.50
IUUC-Xma-133061 Xiphophorus maculatus 94.38 5.00e-47 178.00
IUUC-Yli-134542 Yarrowia lipolytica 67.42 5.00e-34 135.00
IUUC-Zma-135466 Zea mays 94.38 5.00e-47 178.00
Created Date 25-Jun-2017

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