iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000018381.15	ENSMUST00000059026.9	ENSMUSP00000061893.3
ENSMUSG00000018381.15	ENSMUST00000137645.1	ENSMUSP00000119990.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
microRNA	TRANSFAC	RepTar	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	dbPTM	UniProt
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.00e-11	43.8	311	364

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +ekv +ly+y+ q+d+eL++ +G v+ v      + gW++g    ++  G+fP n+ve
   Q: 311  LEKVVTLYPYTRQKDNELSFSEGTVICVT--RRYSDGWCEG--VSSEGTGFFPGNYVE 364
           589*************************7..999*******..688899********8 PP

Organism

Mus musculus

Functional Description
(View)

Inhibits ectopic tumor cell metastasis of SRD cells. In vitro, reduces cell motility.

Protein Sequence
(Fasta)

MAELQQLQQL QEFDIPTGRE ALRGNHSALL RVANYCEDNY LQATDKRKAL EETMAFTTQA 60
LASVAYQVGN LAGHTLRMLD LQGAALRQVE AKMSTLGQMV NMHMEKVARR EIGTLATVVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCAACTAGC TTCCTCTCCA GGACCAGGGA GCAATCACAG ATGCCCCGAC CTTGGCTTCC 60
TTTGCTTGGT GAGATTGAGA GACCGAGCCC CCAACAGGCC CCTGGTTTCC CCCTTCTCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR028457--ABI
IPR028455--ABI3
IPR012849--Abl-interactor_HHR_dom
IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF07815--Abi_HHR
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005622--C:intracellular
GO:0030027--C:lamellipodium
GO:0016020--C:membrane
GO:0030334--P:regulation of cell migration

KEGG

mmu:66610

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002253	Ailuropoda melanoleuca	86.53	8.00e-97	347.00
IUUC-Apl-003887	Anas platyrhynchos	60.27	2.00e-42	166.00
IUUC-Aca-005073	Anolis carolinensis	54.12	2.00e-49	189.00
IUUC-Bta-012731	Bos taurus	88.60	2.00e-99	355.00
IUUC-Cja-019927	Callithrix jacchus	87.37	2.00e-98	352.00
IUUC-Cfa-021246	Canis familiaris	86.30	4.00e-65	241.00
IUUC-Csa-023170	Chlorocebus sabaeus	90.16	4.00e-100	357.00
IUUC-Dno-030080	Dasypus novemcinctus	88.89	3.00e-79	288.00
IUUC-Dor-030777	Dipodomys ordii	89.64	4.00e-92	331.00
IUUC-Ete-032324	Echinops telfairi	86.99	2.00e-73	269.00
IUUC-Eca-034219	Equus caballus	73.54	1.00e-76	280.00
IUUC-Eeu-034475	Erinaceus europaeus	82.72	5.00e-72	264.00
IUUC-Fca-036479	Felis catus	87.05	2.00e-88	319.00
IUUC-Ggo-045520	Gorilla gorilla	89.64	2.00e-99	355.00
IUUC-Hsa-046385	Homo sapiens	90.16	4.00e-100	357.00
IUUC-Itr-048846	Ictidomys tridecemlineatus	89.59	5.00e-104	370.00
IUUC-Laf-053905	Loxodonta africana	89.06	4.00e-98	351.00
IUUC-Mcc-055351	Macaca mulatta	90.67	2.00e-100	359.00
IUUC-Meu-056867	Macropus eugenii	77.71	2.00e-79	289.00
IUUC-Mga-060205	Meleagris gallopavo	60.44	5.00e-53	201.00
IUUC-Mmr-060684	Microcebus murinus	91.71	1.00e-94	339.00
IUUC-Mdo-062899	Monodelphis domestica	74.43	1.00e-90	326.00
IUUC-Mpu-066022	Mustela putorius furo	86.86	2.00e-80	293.00
IUUC-Mlu-067886	Myotis lucifugus	89.64	1.00e-97	350.00
IUUC-Nle-069030	Nomascus leucogenys	90.16	6.00e-100	357.00
IUUC-Opr-070747	Ochotona princeps	88.08	1.00e-97	350.00
IUUC-Ocu-073874	Oryctolagus cuniculus	87.93	1.00e-87	316.00
IUUC-Oga-088294	Otolemur garnettii	87.33	1.00e-100	359.00
IUUC-Oar-089285	Ovis aries	88.36	5.00e-75	275.00
IUUC-Ptr-090972	Pan troglodytes	89.12	4.00e-99	354.00
IUUC-Pan-092463	Papio anubis	90.67	8.00e-94	337.00
IUUC-Pab-098655	Pongo abelii	89.64	1.00e-99	356.00
IUUC-Pca-100627	Procavia capensis	62.44	7.00e-60	224.00
IUUC-Pva-103217	Pteropus vampyrus	78.36	2.00e-66	245.00
IUUC-Rno-105415	Rattus norvegicus	96.55	7.00e-109	387.00
IUUC-Ssc-115938	Sus scrofa	85.34	1.00e-85	310.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence