iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073476

UUCD1 version

UUC-OrA-00230

Ensembl Protein ID

ENSOANP00000013581.1

UniProt Accession

F6VT66; F6VT66_ORNAN

Protein Name

Uncharacterized protein

Gene Name

KLHL41

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000008534.2	ENSOANT00000013584.2	ENSOANP00000013581.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.40e-16	60.8	34	100
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.20e-10	40.5	132	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           D++l+ g++  ++h+++L+a+S++F+  fl+e +e k k++++++ v+p  +  ++k+lY+ ++d+n+
   Q: 34   DCTLKAGDKSLPCHRLILSACSPYFREYFLSEISEDK-KKEMVLDNVDPALLDLIIKYLYSASIDLND 100
           9***********************************9.99999999*******************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           + Ncl+ilr++ l+dcp+L+++a++f+++ F
   Q: 132  PGNCLAILRLGLLLDCPRLALSAREFVSDRF 162
           56***************************99 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MDSQRELTEE LRLYQSTLLQ DGLKDLLDEK KFIDCTLKAG DKSLPCHRLI LSACSPYFRE 60
YFLSEISEDK KKEMVLDNVD PALLDLIIKY LYSASIDLND GNVQDIFALA SRFQIPSVFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCCAAAAG TAACTGATAC AGAGACAGCT CTCCTATGAG CAATGCGCTG TTCATTTTGC 60
CTGCCTAGCA ATTTGCATAC CACACAAAAT TTTGAAGAAG CTTCTTTACC ATTCTGATTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030571--KLHL41
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0031430--C:M band
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0033017--C:sarcoplasmic reticulum membrane
GO:0016567--P:protein ubiquitination
GO:0045661--P:regulation of myoblast differentiation
GO:2000291--P:regulation of myoblast proliferation
GO:2001014--P:regulation of skeletal muscle cell differentiation
GO:0045214--P:sarcomere organization
GO:0035914--P:skeletal muscle cell differentiation
GO:0048741--P:skeletal muscle fiber development

KEGG

oaa:100083421

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002167	Ailuropoda melanoleuca	92.90	0.00e+00	1142.00
IUUC-Apl-003866	Anas platyrhynchos	84.82	0.00e+00	1044.00
IUUC-Aca-005275	Anolis carolinensis	50.72	2.00e-178	618.00
IUUC-Ame-011172	Astyanax mexicanus	61.53	0.00e+00	757.00
IUUC-Bta-012925	Bos taurus	93.07	0.00e+00	1141.00
IUUC-Bci-013875	Botrytis cinerea	28.44	6.00e-17	80.90
IUUC-Bdi-014115	Brachypodium distachyon	24.05	4.00e-11	61.60
IUUC-Cja-019348	Callithrix jacchus	92.08	0.00e+00	1137.00
IUUC-Cfa-020782	Canis familiaris	93.73	0.00e+00	1151.00
IUUC-Cpo-021825	Cavia porcellus	91.91	0.00e+00	1129.00
IUUC-Csa-023184	Chlorocebus sabaeus	92.51	0.00e+00	975.00
IUUC-Cin-025237	Ciona intestinalis	28.64	1.00e-67	249.00
IUUC-Dre-028278	Danio rerio	59.93	0.00e+00	775.00
IUUC-Dno-029516	Dasypus novemcinctus	92.90	0.00e+00	1143.00
IUUC-Dor-030850	Dipodomys ordii	88.19	0.00e+00	731.00
IUUC-Ete-032697	Echinops telfairi	91.09	0.00e+00	1100.00
IUUC-Eca-033714	Equus caballus	93.23	0.00e+00	1144.00
IUUC-Eeu-035245	Erinaceus europaeus	90.51	0.00e+00	1033.00
IUUC-Fca-035823	Felis catus	45.28	2.00e-161	561.00
IUUC-Fal-037632	Ficedula albicollis	55.65	0.00e+00	682.00
IUUC-Gmo-039392	Gadus morhua	57.47	0.00e+00	735.00
IUUC-Ggr-040041	Gaeumannomyces graminis	27.08	5.00e-08	51.20
IUUC-Gga-041106	Gallus gallus	84.49	0.00e+00	1060.00
IUUC-Gac-042252	Gasterosteus aculeatus	60.70	0.00e+00	774.00
IUUC-Ggo-044817	Gorilla gorilla	92.74	0.00e+00	1140.00
IUUC-Hsa-046620	Homo sapiens	92.74	0.00e+00	1140.00
IUUC-Itr-048612	Ictidomys tridecemlineatus	51.52	0.00e+00	677.00
IUUC-Lch-050477	Latimeria chalumnae	69.64	0.00e+00	860.00
IUUC-Loc-051955	Lepisosteus oculatus	69.97	0.00e+00	912.00
IUUC-Laf-053500	Loxodonta africana	93.23	0.00e+00	1144.00
IUUC-Mcc-055316	Macaca mulatta	92.57	0.00e+00	1139.00
IUUC-Meu-055972	Macropus eugenii	51.87	0.00e+00	655.00
IUUC-Mga-059451	Meleagris gallopavo	56.86	0.00e+00	712.00
IUUC-Mmr-061444	Microcebus murinus	92.90	0.00e+00	1142.00
IUUC-Mdo-062563	Monodelphis domestica	53.22	6.00e-144	503.00
IUUC-Mmu-064147	Mus musculus	92.74	0.00e+00	1139.00
IUUC-Mpu-066262	Mustela putorius furo	51.05	0.00e+00	663.00
IUUC-Mlu-067481	Myotis lucifugus	92.24	0.00e+00	1127.00
IUUC-Nle-069339	Nomascus leucogenys	92.90	0.00e+00	1142.00
IUUC-Opr-070703	Ochotona princeps	92.74	0.00e+00	1097.00
IUUC-Ont-072420	Oreochromis niloticus	60.13	0.00e+00	796.00
IUUC-Ocu-074248	Oryctolagus cuniculus	93.23	0.00e+00	1152.00
IUUC-Ola-086361	Oryzias latipes	62.00	0.00e+00	784.00
IUUC-Oga-088855	Otolemur garnettii	50.49	0.00e+00	661.00
IUUC-Oar-090349	Ovis aries	92.74	0.00e+00	1139.00
IUUC-Ptr-091028	Pan troglodytes	49.65	7.00e-123	433.00
IUUC-Pan-092069	Papio anubis	92.74	0.00e+00	1140.00
IUUC-Psi-093671	Pelodiscus sinensis	87.95	0.00e+00	1054.00
IUUC-Pma-094586	Petromyzon marinus	57.14	2.00e-93	334.00
IUUC-Pfo-096122	Poecilia formosa	61.46	0.00e+00	806.00
IUUC-Pab-098711	Pongo abelii	92.57	0.00e+00	1139.00
IUUC-Pca-100495	Procavia capensis	85.15	0.00e+00	1021.00
IUUC-Pva-102401	Pteropus vampyrus	92.74	0.00e+00	1139.00
IUUC-Rno-105969	Rattus norvegicus	92.90	0.00e+00	1142.00
IUUC-Sha-107091	Sarcophilus harrisii	52.31	0.00e+00	679.00
IUUC-Sar-113405	Sorex araneus	90.76	0.00e+00	1103.00
IUUC-Ssc-116276	Sus scrofa	50.56	0.00e+00	657.00
IUUC-Tgu-116725	Taeniopygia guttata	84.82	0.00e+00	1078.00
IUUC-Tru-117743	Takifugu rubripes	59.54	0.00e+00	764.00
IUUC-Tsy-119225	Tarsius syrichta	86.80	0.00e+00	1047.00
IUUC-Tni-120547	Tetraodon nigroviridis	61.96	0.00e+00	791.00
IUUC-Tbe-127806	Tupaia belangeri	46.20	1.00e-165	575.00
IUUC-Ttr-128645	Tursiops truncatus	92.57	0.00e+00	1138.00
IUUC-Vpa-130714	Vicugna pacos	93.23	0.00e+00	1147.00
IUUC-Xtr-132144	Xenopus tropicalis	76.40	0.00e+00	950.00
IUUC-Xma-133253	Xiphophorus maculatus	62.60	0.00e+00	808.00
IUUC-Yli-134535	Yarrowia lipolytica	23.64	2.00e-06	45.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence