iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118614

UUCD1 version

UUC-TaR-00971

Ensembl Protein ID

ENSTRUP00000045034.1

UniProt Accession

H2V745; H2V745_TAKRU

Protein Name

Uncharacterized protein

Gene Name

klhl40b; klhl40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000017569.1	ENSTRUT00000045186.1	ENSTRUP00000045034.1
ENSTRUG00000017569.1	ENSTRUT00000045187.1	ENSTRUP00000045035.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.30e-23	83.0	34	99
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.90e-08	32.5	132	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           D++l+++++ef++h++vL+a+Ss+F+a fl++leesk k++++++dv+p+v+  +lk+lYt+k++ +
   Q: 34   DCVLKIKDKEFPCHRLVLCACSSYFRAIFLSDLEESK-KKEIVLEDVEPGVMGLILKYLYTSKINVT 99
           9************************************.*************************9876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           l+Ncl+++r++ ++dcp+L+ +a+++++  F
   Q: 132  LSNCLAVFRLGLMLDCPRLAISARNYACERF 162
           69**************************988 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MALPINPTDE PRVYQQTLLQ DGLYDLLEND KLVDCVLKIK DKEFPCHRLV LCACSSYFRA 60
IFLSDLEESK KKEIVLEDVE PGVMGLILKY LYTSKINVTE HNVQDIFAVA NMYQIPSIFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCACTGC CGATCAACCC GACGGACGAG CCGAGGGTGT ACCAGCAGAC GCTGCTCCAG 60
GATGGCCTGT ACGACCTGCT GGAGAATGAC AAGCTGGTGG ACTGCGTCCT GAAGATCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030607--KLHL40
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031672--C:A band
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0031674--C:I band
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031397--P:negative regulation of protein ubiquitination
GO:0016567--P:protein ubiquitination
GO:0048741--P:skeletal muscle fiber development
GO:0036268--P:swimming

KEGG

tru:101078471

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001792	Ailuropoda melanoleuca	55.50	0.00e+00	705.00
IUUC-Apl-003748	Anas platyrhynchos	66.77	0.00e+00	839.00
IUUC-Aca-005275	Anolis carolinensis	59.24	0.00e+00	743.00
IUUC-Ame-011294	Astyanax mexicanus	71.47	0.00e+00	928.00
IUUC-Bta-012801	Bos taurus	59.49	0.00e+00	772.00
IUUC-Cja-019795	Callithrix jacchus	58.70	0.00e+00	679.00
IUUC-Cpo-022436	Cavia porcellus	59.38	0.00e+00	770.00
IUUC-Csa-023105	Chlorocebus sabaeus	59.78	0.00e+00	754.00
IUUC-Dre-028077	Danio rerio	70.39	0.00e+00	899.00
IUUC-Eca-034393	Equus caballus	58.46	0.00e+00	720.00
IUUC-Fca-035823	Felis catus	51.38	0.00e+00	644.00
IUUC-Fal-037632	Ficedula albicollis	66.40	0.00e+00	820.00
IUUC-Gmo-039697	Gadus morhua	76.26	0.00e+00	990.00
IUUC-Gga-040525	Gallus gallus	65.81	0.00e+00	832.00
IUUC-Gac-042421	Gasterosteus aculeatus	83.82	0.00e+00	1077.00
IUUC-Ggo-045596	Gorilla gorilla	59.46	0.00e+00	750.00
IUUC-Hsa-046235	Homo sapiens	59.46	0.00e+00	747.00
IUUC-Itr-048612	Ictidomys tridecemlineatus	59.74	0.00e+00	781.00
IUUC-Lch-050123	Latimeria chalumnae	67.55	0.00e+00	874.00
IUUC-Loc-051824	Lepisosteus oculatus	70.95	0.00e+00	924.00
IUUC-Mcc-054909	Macaca mulatta	59.46	0.00e+00	752.00
IUUC-Meu-055972	Macropus eugenii	59.62	0.00e+00	763.00
IUUC-Mtr-058084	Medicago truncatula	32.20	2.00e-14	73.20
IUUC-Mga-059451	Meleagris gallopavo	65.81	0.00e+00	841.00
IUUC-Mmr-060736	Microcebus murinus	59.65	0.00e+00	774.00
IUUC-Mdo-062563	Monodelphis domestica	60.54	4.00e-174	604.00
IUUC-Mmu-063549	Mus musculus	59.94	0.00e+00	780.00
IUUC-Mpu-066262	Mustela putorius furo	59.65	0.00e+00	777.00
IUUC-Mlu-067210	Myotis lucifugus	59.58	0.00e+00	773.00
IUUC-Opr-070384	Ochotona princeps	57.03	0.00e+00	705.00
IUUC-Ont-071273	Oreochromis niloticus	83.74	0.00e+00	1056.00
IUUC-Ocu-074499	Oryctolagus cuniculus	60.00	0.00e+00	753.00
IUUC-Ola-087175	Oryzias latipes	81.08	0.00e+00	1055.00
IUUC-Oga-088855	Otolemur garnettii	59.65	0.00e+00	776.00
IUUC-Ptr-091028	Pan troglodytes	56.04	9.00e-142	496.00
IUUC-Pan-091827	Papio anubis	59.78	0.00e+00	754.00
IUUC-Psi-092998	Pelodiscus sinensis	65.70	0.00e+00	816.00
IUUC-Pma-094586	Petromyzon marinus	61.57	1.00e-97	349.00
IUUC-Pfo-096216	Poecilia formosa	80.88	0.00e+00	1053.00
IUUC-Sha-107091	Sarcophilus harrisii	60.53	0.00e+00	797.00
IUUC-Ssl-108429	Sclerotinia sclerotiorum	29.25	5.00e-08	51.60
IUUC-Ssc-116276	Sus scrofa	59.33	0.00e+00	767.00
IUUC-Tgu-116494	Taeniopygia guttata	66.29	0.00e+00	846.00
IUUC-Tni-119776	Tetraodon nigroviridis	91.64	0.00e+00	1143.00
IUUC-Tbe-127806	Tupaia belangeri	54.72	0.00e+00	689.00
IUUC-Ttr-128813	Tursiops truncatus	58.95	0.00e+00	761.00
IUUC-Xtr-132942	Xenopus tropicalis	64.72	0.00e+00	831.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence