iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.70e-13	49.8	221	299

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 1    evpeeflCpIslelMrdPvvlpsGitydrssIekwlasggk.....tcPvtrqpl.teedlvPnltlrrliqawceens 73
           ++peefl++I+ elM  P+vlpsG ++d+s+I k+ ++  k     ++P+t+ ++ ++++ + +l+l++ i++++ ens
   Q: 221  SIPEEFLDSITWELMIFPTVLPSGKVVDQSTIDKHAEEEAKwgrqpSDPFTGLEFnAQRKAILHLALKARIEKFLMENS 299
           59*********************************9999889999**********666677**************9997 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSSLINFLNP KLKPSVETDA VCEDGYTAAN LVADDVEQLE RGFMCFAVCK PPIEIVFDFP 60
KAVDMKVIKL WPSCGALRST AFELHGRHDG IWERVAFVRD LGRGVDSVTF CYQSDYNSRS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATTTTAACT CATTCAATTT TTGCCGCCCA AGCGAATAGG TGTTACCGTA CGCGAGTACT 60
GAGCGAAGTC CATCTGACTG GTCGCACCAC CACTACCGCC CGGGCATGGT CACACTGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR008979--Galactose-bd-like
IPR003613--Ubox_domain
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1

Pfam

PF04564--U-box

SMART

SM00504--Ubox

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0016567--P:protein ubiquitination

KEGG

dme:Dmel_CG2218

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001702	Ailuropoda melanoleuca	38.46	4.00e-25	108.00
IUUC-Apl-003809	Anas platyrhynchos	27.72	7.00e-32	130.00
IUUC-Ame-011326	Astyanax mexicanus	25.86	3.00e-27	115.00
IUUC-Bta-012836	Bos taurus	27.35	2.00e-31	129.00
IUUC-Cja-018735	Callithrix jacchus	26.51	2.00e-06	46.60
IUUC-Cfa-020914	Canis familiaris	26.41	1.00e-29	123.00
IUUC-Cpo-022397	Cavia porcellus	27.81	9.00e-32	130.00
IUUC-Csa-023033	Chlorocebus sabaeus	28.53	4.00e-30	125.00
IUUC-Cho-025050	Choloepus hoffmanni	38.06	3.00e-24	105.00
IUUC-Csv-025960	Ciona savignyi	22.71	1.00e-08	52.80
IUUC-Dre-028494	Danio rerio	26.60	1.00e-24	107.00
IUUC-Dno-029134	Dasypus novemcinctus	39.86	8.00e-24	103.00
IUUC-Eca-033535	Equus caballus	27.51	2.00e-31	129.00
IUUC-Fca-036298	Felis catus	27.06	3.00e-30	125.00
IUUC-Fal-037385	Ficedula albicollis	29.06	3.00e-32	132.00
IUUC-Gmo-039572	Gadus morhua	35.16	6.00e-17	81.30
IUUC-Gga-040207	Gallus gallus	28.49	5.00e-33	134.00
IUUC-Gac-042339	Gasterosteus aculeatus	37.78	7.00e-19	87.80
IUUC-Ggo-044710	Gorilla gorilla	39.61	3.00e-24	105.00
IUUC-Hsa-045766	Homo sapiens	28.53	8.00e-30	124.00
IUUC-Itr-048280	Ictidomys tridecemlineatus	38.71	3.00e-25	108.00
IUUC-Lch-050587	Latimeria chalumnae	28.31	1.00e-31	130.00
IUUC-Mcc-055661	Macaca mulatta	39.61	3.00e-25	108.00
IUUC-Meu-055959	Macropus eugenii	42.67	2.00e-26	112.00
IUUC-Mga-059505	Meleagris gallopavo	23.29	5.00e-25	108.00
IUUC-Mmr-061218	Microcebus murinus	37.74	2.00e-24	106.00
IUUC-Mdo-062113	Monodelphis domestica	27.99	2.00e-33	135.00
IUUC-Mmu-063349	Mus musculus	25.30	3.00e-06	46.20
IUUC-Mpu-066189	Mustela putorius furo	37.11	5.00e-24	104.00
IUUC-Mlu-067083	Myotis lucifugus	28.02	2.00e-31	129.00
IUUC-Nle-069481	Nomascus leucogenys	28.36	1.00e-06	47.40
IUUC-Opr-070674	Ochotona princeps	28.48	1.00e-27	117.00
IUUC-Ont-071995	Oreochromis niloticus	38.89	6.00e-22	97.80
IUUC-Oan-073003	Ornithorhynchus anatinus	43.62	3.00e-26	112.00
IUUC-Ocu-073834	Oryctolagus cuniculus	37.11	4.00e-25	108.00
IUUC-Ola-086469	Oryzias latipes	36.62	7.00e-17	81.30
IUUC-Oga-088316	Otolemur garnettii	39.61	4.00e-25	108.00
IUUC-Oar-089563	Ovis aries	38.96	1.00e-25	110.00
IUUC-Ptr-091293	Pan troglodytes	28.53	9.00e-30	124.00
IUUC-Pan-092705	Papio anubis	28.53	5.00e-31	128.00
IUUC-Psi-093111	Pelodiscus sinensis	28.46	1.00e-32	133.00
IUUC-Pfo-096603	Poecilia formosa	46.81	3.00e-19	89.40
IUUC-Pab-098636	Pongo abelii	38.96	3.00e-24	105.00
IUUC-Pca-100109	Procavia capensis	38.99	1.00e-25	110.00
IUUC-Pva-103028	Pteropus vampyrus	37.91	5.00e-24	104.00
IUUC-Rno-104883	Rattus norvegicus	28.32	5.00e-32	131.00
IUUC-Sha-107133	Sarcophilus harrisii	40.38	1.00e-24	107.00
IUUC-Ssc-116252	Sus scrofa	36.57	3.00e-25	108.00
IUUC-Tgu-117163	Taeniopygia guttata	29.33	2.00e-33	135.00
IUUC-Tru-118541	Takifugu rubripes	38.10	8.00e-22	97.80
IUUC-Tsy-119281	Tarsius syrichta	47.27	7.00e-23	100.00
IUUC-Tni-120789	Tetraodon nigroviridis	35.33	2.00e-21	96.30
IUUC-Ttr-128555	Tursiops truncatus	26.82	9.00e-31	127.00
IUUC-Xtr-132303	Xenopus tropicalis	38.42	9.00e-28	117.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence