iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062224

Ensembl Protein ID

ENSMODP00000026913.3

UniProt Accession

F7DZQ4; F7DZQ4_MONDO

Protein Name

Uncharacterized protein

Gene Name

EML2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000021541.3	ENSMODT00000027395.3	ENSMODP00000026913.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.10e-19	67.8	476	505

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H+++v++l+   d tl++ G++D  + +W 
   Q: 476  HEGGVFGLCVlRDgTLVSGGGRDRRVVLWG 505
           9********888846555588********6 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MATGGRARAG IAAMSERERE PGPACPPSLY DTASLLRFCH DDSLSGSGME VDDRVSALEQ 60
RLQLQEDELA VLKAALADAL RRLRVCEEQG TAIRARGTPK GRAPLRLGPA ATVCQLLKGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGTTAGGGA TCCGGGCAGC CCCTGGCTCT AAGCATCCCT GGCTCTGCTG TAGCCCCATT 60
GGCCGGAGAG CAGCCAATCA GCAGGCTGAG GTGGGGAGAG CCCGGGGTCT GAGGTAGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0015630--C:microtubule cytoskeleton
GO:0072686--C:mitotic spindle
GO:0008017--F:microtubule binding
GO:0031115--P:negative regulation of microtubule polymerization
GO:0010968--P:regulation of microtubule nucleation

KEGG

mdo:100011401

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002155	Ailuropoda melanoleuca	85.87	0.00e+00	1174.00
IUUC-Aca-005316	Anolis carolinensis	75.03	0.00e+00	1027.00
IUUC-Bta-013267	Bos taurus	85.03	0.00e+00	1196.00
IUUC-Cja-019146	Callithrix jacchus	82.04	0.00e+00	986.00
IUUC-Cfa-020267	Canis familiaris	85.97	0.00e+00	1208.00
IUUC-Dno-028961	Dasypus novemcinctus	84.63	0.00e+00	1143.00
IUUC-Eca-033785	Equus caballus	84.43	0.00e+00	1177.00
IUUC-Fca-036170	Felis catus	83.06	0.00e+00	1143.00
IUUC-Ggo-044669	Gorilla gorilla	82.74	0.00e+00	1130.00
IUUC-Hsa-046141	Homo sapiens	86.84	0.00e+00	1215.00
IUUC-Itr-048788	Ictidomys tridecemlineatus	84.92	0.00e+00	1190.00
IUUC-Laf-054137	Loxodonta africana	82.53	0.00e+00	951.00
IUUC-Mcc-055780	Macaca mulatta	87.68	0.00e+00	1038.00
IUUC-Meu-056664	Macropus eugenii	91.41	0.00e+00	1055.00
IUUC-Mmr-060853	Microcebus murinus	85.73	0.00e+00	1199.00
IUUC-Mmu-063860	Mus musculus	85.73	0.00e+00	1202.00
IUUC-Mpu-066043	Mustela putorius furo	86.17	0.00e+00	1201.00
IUUC-Mlu-067125	Myotis lucifugus	65.82	0.00e+00	789.00
IUUC-Nle-069618	Nomascus leucogenys	77.67	0.00e+00	1011.00
IUUC-Opr-070228	Ochotona princeps	78.71	0.00e+00	913.00
IUUC-Oga-088048	Otolemur garnettii	82.56	0.00e+00	1144.00
IUUC-Oar-089907	Ovis aries	87.66	0.00e+00	1014.00
IUUC-Pan-092082	Papio anubis	85.29	0.00e+00	1196.00
IUUC-Pab-097619	Pongo abelii	88.55	0.00e+00	1052.00
IUUC-Pca-101070	Procavia capensis	80.04	0.00e+00	875.00
IUUC-Pva-102957	Pteropus vampyrus	83.27	0.00e+00	973.00
IUUC-Rno-105074	Rattus norvegicus	87.30	0.00e+00	1020.00
IUUC-Sha-106692	Sarcophilus harrisii	90.95	0.00e+00	1179.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence