iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028099

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ring finger protein 144B

Genbank Nucleotide ID

CABZ01038326

Gene Name

rnf144b

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000024940.5	ENSDART00000032778.5	ENSDARP00000034051.6

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	9.70e-42	143.7	30	222

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+  +  e+ +l++C+++fC +Cl+qy++l+i+ g  ++i+cp+++c+++  l +se+++  + +++++ y++l +e+ v+ d++ 
   Q: 30   CKLCLSDWPEAETCTLQSCSCVFCAQCLRQYVQLAIRAGAGSAITCPDPACKNSgtLLDSELAS-FAPSDQVELYQRLRFERGVQLDPSK 118
           ***************************************************99877899*****.79999******************** PP
   S: 89   kwcpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
            wcp   C++v+ +++ +  + + v+c+ c+++fC+ C++ w +g sC+  +  +       + a s+  +ea +k+Cp C vyie+n+g
   Q: 119  AWCPVLACQAVCSVTPGTegTPVPVPCPVCQTVFCCGCRSPWSDGHSCSLQQPLMPPLP---DGALSSDDTEAAIKQCPVCGVYIERNQG 205
           **************998755777788**********************98877777766...8999************************ PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m C++Ck++fCw+C
   Q: 206  CAQMLCKSCKHTFCWYC 222
           ***************** PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MESFTPMFLR YRNKPQQKAS MDGKSTTIHC KLCLSDWPEA ETCTLQSCSC VFCAQCLRQY 60
VQLAIRAGAG SAITCPDPAC KNSGTLLDSE LASFAPSDQV ELYQRLRFER GVQLDPSKAW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGACTGGG CGCAGATATA AAGCAGACCC GACTGACTGT CCATCATCAT CTTCAGCATC 60
TTCATGATCA GATGCGCGTG AGGATGCACA CACTCCAGTC ATGGCCATGA ATACTGAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001257	Ailuropoda melanoleuca	65.79	1.00e-100	359.00
IUUC-Apl-004112	Anas platyrhynchos	62.99	9.00e-89	320.00
IUUC-Aca-004533	Anolis carolinensis	63.16	4.00e-100	357.00
IUUC-Bta-012641	Bos taurus	64.29	1.00e-97	349.00
IUUC-Cja-019626	Callithrix jacchus	60.07	6.00e-87	313.00
IUUC-Cfa-020702	Canis familiaris	64.66	6.00e-99	353.00
IUUC-Cpo-022147	Cavia porcellus	65.79	6.00e-99	353.00
IUUC-Csa-023473	Chlorocebus sabaeus	65.41	8.00e-99	353.00
IUUC-Cho-024298	Choloepus hoffmanni	63.48	1.00e-83	302.00
IUUC-Dno-029122	Dasypus novemcinctus	60.30	5.00e-89	321.00
IUUC-Dor-030669	Dipodomys ordii	67.26	8.00e-86	309.00
IUUC-Ete-033141	Echinops telfairi	53.01	2.00e-67	249.00
IUUC-Eca-034360	Equus caballus	65.41	7.00e-100	356.00
IUUC-Eeu-034538	Erinaceus europaeus	56.65	2.00e-59	222.00
IUUC-Fca-036055	Felis catus	64.31	3.00e-98	351.00
IUUC-Fal-037339	Ficedula albicollis	63.49	5.00e-95	340.00
IUUC-Gmo-038780	Gadus morhua	70.96	2.00e-102	365.00
IUUC-Gga-040256	Gallus gallus	62.20	1.00e-92	333.00
IUUC-Gac-042127	Gasterosteus aculeatus	76.05	5.00e-105	374.00
IUUC-Ggo-044867	Gorilla gorilla	65.41	7.00e-99	353.00
IUUC-Hsa-046928	Homo sapiens	65.41	7.00e-99	353.00
IUUC-Hvu-047484	Hordeum vulgare	30.88	3.00e-18	86.70
IUUC-Itr-048250	Ictidomys tridecemlineatus	70.88	1.00e-72	265.00
IUUC-Lch-050168	Latimeria chalumnae	61.48	6.00e-96	343.00
IUUC-Lpe-051649	Leersia perrieri	30.00	6.00e-19	89.70
IUUC-Loc-052150	Lepisosteus oculatus	70.36	2.00e-94	338.00
IUUC-Laf-053967	Loxodonta africana	65.41	6.00e-100	357.00
IUUC-Mcc-055898	Macaca mulatta	65.41	8.00e-99	353.00
IUUC-Meu-056628	Macropus eugenii	87.18	2.00e-38	152.00
IUUC-Mga-059820	Meleagris gallopavo	61.81	2.00e-92	332.00
IUUC-Mmr-060680	Microcebus murinus	65.04	8.00e-99	353.00
IUUC-Mdo-062839	Monodelphis domestica	63.30	1.00e-97	349.00
IUUC-Mmu-063339	Mus musculus	62.41	6.00e-89	320.00
IUUC-Mac-065414	Musa acuminata	27.43	1.00e-17	84.00
IUUC-Mpu-065973	Mustela putorius furo	65.04	8.00e-100	356.00
IUUC-Mlu-067112	Myotis lucifugus	64.20	1.00e-94	339.00
IUUC-Nle-069795	Nomascus leucogenys	65.41	3.00e-99	354.00
IUUC-Opr-070390	Ochotona princeps	59.77	2.00e-84	305.00
IUUC-Ont-072329	Oreochromis niloticus	67.72	1.00e-103	369.00
IUUC-Oan-072980	Ornithorhynchus anatinus	64.66	5.00e-100	357.00
IUUC-Ocu-073845	Oryctolagus cuniculus	65.04	5.00e-100	357.00
IUUC-Ola-086872	Oryzias latipes	73.41	5.00e-101	360.00
IUUC-Oga-088954	Otolemur garnettii	64.66	5.00e-98	350.00
IUUC-Oar-089879	Ovis aries	64.29	1.00e-97	349.00
IUUC-Ptr-090685	Pan troglodytes	65.41	7.00e-99	353.00
IUUC-Pan-092086	Papio anubis	65.04	9.00e-99	353.00
IUUC-Psi-093481	Pelodiscus sinensis	58.36	7.00e-93	333.00
IUUC-Pfo-096065	Poecilia formosa	68.94	8.00e-103	366.00
IUUC-Pab-098031	Pongo abelii	65.41	1.00e-98	353.00
IUUC-Pca-100936	Procavia capensis	65.79	2.00e-101	361.00
IUUC-Pva-102864	Pteropus vampyrus	57.14	3.00e-82	298.00
IUUC-Rno-105503	Rattus norvegicus	62.41	3.00e-89	321.00
IUUC-Sha-107425	Sarcophilus harrisii	64.79	4.00e-100	357.00
IUUC-Ssc-115458	Sus scrofa	64.57	1.00e-93	336.00
IUUC-Tgu-117226	Taeniopygia guttata	63.10	2.00e-95	342.00
IUUC-Tru-118362	Takifugu rubripes	70.24	4.00e-108	384.00
IUUC-Tsy-119255	Tarsius syrichta	65.04	2.00e-99	355.00
IUUC-Tni-120140	Tetraodon nigroviridis	73.03	7.00e-102	363.00
IUUC-Tae-124420	Triticum aestivum	30.88	2.00e-19	90.50
IUUC-Tbe-127306	Tupaia belangeri	65.04	5.00e-99	353.00
IUUC-Ttr-128923	Tursiops truncatus	64.57	3.00e-92	331.00
IUUC-Vpa-130148	Vicugna pacos	64.66	2.00e-98	351.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence