iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098540

UUCD1 version

UUC-PoA-00938

Ensembl Protein ID

ENSPPYP00000014710.2

UniProt Accession

Q5RCG7; Q5RA18; AAMP_PONAB

Genbank Protein ID

CAH90540.1; CAH91392.1

Protein Name

Angio-associated migratory cell protein

Genbank Nucleotide ID

CR858303; CR859206

Gene Name

AAMP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000013166.2	ENSPPYT00000015307.2	ENSPPYP00000014710.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.90e-33	111.0	90	127
UBD/Beta-Prp	3.80e-49	167.6	89	299

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlrtgvll 36
           H++sv+c+++   ++tl v+G+ D +  vW+l++g ll
   Q: 90   HSASVFCVSLdpkTNTLAVTGGEDDKAFVWRLSDGELL 127
           99*********8655999**************999875 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkf.spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
            h  sv  cv    + ++l +tg++d++  vw++++g ll +  gh++ vt+  fs+d+ + +tg   +++kvw ++t + v +++   
   Q: 89   LHSASVF-CVSLdPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSFE--A 174
           4444455.577735556666899************************************9**************************..8 PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgghtd 181
            ++  ++++p   +l++G++d    +w++++g c   t++g +   +c +v pdg+  v G  D+t+r+Wdlk+g+ ++ l  t+gh++
   Q: 175  GDLEWMEWHPRAPVLLAGTADGNTWMWKVPNGDCK--TFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLkgTEGHQG 261
           9999******************************9..7*******************************************99677*** PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
           + ++++ +++g  +++gs d + kl++  tg++v  ++
   Q: 262  PLTCVATNQDGSLILTGSVDCQAKLVSATTGKVVGVFR 299
           ********************************998765 PP

Organism

Pongo abelii

Functional Description
(View)

Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway (By similarity).

Protein Sequence
(Fasta)

MESESESGAA ADTPPLETLS FHGDEEIIEV VELDPGPPDP DDLAQEMEDV DFEEEEEEEG 60
NEEGWVLEPQ EGVVGSMEGP DDSEVTFALH SASVFCVSLD PKTNTLAVTG GEDDKAFVWR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGTCCG AATCGGAAAG CGGGGCTGCT GCTGACACCC CCCCACTGGA GACCCTAAGC 60
TTCCATGGTG ACGAAGAGAT TATCGAGGTG GTAGAACTTG ATCCCGGTCC GCCGGACCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0037--Angiogenesis
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0217--Developmental protein
KW-0221--Differentiation
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0009986--C:cell surface
GO:0005829--C:cytosol
GO:0045171--C:intercellular bridge
GO:0015630--C:microtubule cytoskeleton
GO:0005886--C:plasma membrane
GO:0001525--P:angiogenesis
GO:0030154--P:cell differentiation
GO:0010595--P:positive regulation of endothelial cell migration
GO:0014909--P:smooth muscle cell migration

KEGG

pon:100172186

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000794	Aegilops tauschii	34.91	3.00e-57	216.00
IUUC-Aml-001781	Ailuropoda melanoleuca	93.12	0.00e+00	750.00
IUUC-Atr-003169	Amborella trichopoda	35.82	6.00e-61	227.00
IUUC-Apl-003939	Anas platyrhynchos	66.96	5.00e-115	407.00
IUUC-Aca-004594	Anolis carolinensis	83.62	9.00e-176	609.00
IUUC-Aly-006277	Arabidopsis lyrata	31.25	6.00e-48	184.00
IUUC-Ath-007701	Arabidopsis thaliana	33.43	4.00e-56	211.00
IUUC-Ame-011651	Astyanax mexicanus	56.44	3.00e-135	474.00
IUUC-Bgr-012118	Blumeria graminis	22.82	7.00e-18	85.10
IUUC-Bta-012833	Bos taurus	98.85	0.00e+00	758.00
IUUC-Bdi-014289	Brachypodium distachyon	35.21	3.00e-62	232.00
IUUC-Bol-015313	Brassica oleracea	32.29	7.00e-53	201.00
IUUC-Bra-017115	Brassica rapa	31.43	5.00e-43	168.00
IUUC-Cel-018305	Caenorhabditis elegans	32.10	8.00e-38	150.00
IUUC-Cja-019433	Callithrix jacchus	98.62	0.00e+00	756.00
IUUC-Cfa-020093	Canis familiaris	97.01	0.00e+00	765.00
IUUC-Cpo-021742	Cavia porcellus	96.78	0.00e+00	758.00
IUUC-Cre-022781	Chlamydomonas reinhardtii	33.24	1.00e-42	166.00
IUUC-Csa-023498	Chlorocebus sabaeus	98.85	0.00e+00	754.00
IUUC-Cho-024628	Choloepus hoffmanni	97.77	4.00e-177	613.00
IUUC-Cin-025244	Ciona intestinalis	46.44	3.00e-85	308.00
IUUC-Csv-026218	Ciona savignyi	46.44	8.00e-88	317.00
IUUC-Cne-026911	Cryptococcus neoformans	27.23	3.00e-26	112.00
IUUC-Dre-028528	Danio rerio	65.25	1.00e-139	489.00
IUUC-Dno-029297	Dasypus novemcinctus	94.28	0.00e+00	758.00
IUUC-Dor-030543	Dipodomys ordii	97.16	1.00e-65	243.00
IUUC-Dme-031587	Drosophila melanogaster	31.28	4.00e-45	175.00
IUUC-Ete-033100	Echinops telfairi	81.96	1.00e-136	478.00
IUUC-Eca-034277	Equus caballus	96.71	0.00e+00	736.00
IUUC-Eeu-035052	Erinaceus europaeus	98.55	1.00e-106	379.00
IUUC-Fca-036115	Felis catus	97.01	0.00e+00	763.00
IUUC-Fal-036864	Ficedula albicollis	82.09	1.00e-177	615.00
IUUC-Gmo-039090	Gadus morhua	57.89	4.00e-99	354.00
IUUC-Gga-040545	Gallus gallus	79.57	0.00e+00	627.00
IUUC-Gac-042027	Gasterosteus aculeatus	63.08	1.00e-141	496.00
IUUC-Gma-044168	Glycine max	35.92	7.00e-58	217.00
IUUC-Ggo-045036	Gorilla gorilla	98.85	0.00e+00	754.00
IUUC-Hsa-046749	Homo sapiens	98.85	0.00e+00	754.00
IUUC-Hvu-047217	Hordeum vulgare	34.96	5.00e-59	221.00
IUUC-Itr-048114	Ictidomys tridecemlineatus	96.55	0.00e+00	755.00
IUUC-Kpa-049147	Komagataella pastoris	25.20	4.00e-24	105.00
IUUC-Lch-049747	Latimeria chalumnae	62.32	7.00e-138	483.00
IUUC-Lpe-051433	Leersia perrieri	32.73	2.00e-53	203.00
IUUC-Loc-052406	Lepisosteus oculatus	69.30	3.00e-161	561.00
IUUC-Lma-053153	Leptosphaeria maculans	27.75	4.00e-15	75.90
IUUC-Laf-053901	Loxodonta africana	97.01	0.00e+00	758.00
IUUC-Mcc-054990	Macaca mulatta	100.00	0.00e+00	711.00
IUUC-Meu-056844	Macropus eugenii	87.62	0.00e+00	660.00
IUUC-Mtr-057759	Medicago truncatula	37.18	5.00e-59	221.00
IUUC-Mla-058856	Melampsora laricipopulina	29.17	1.00e-36	147.00
IUUC-Mga-059749	Meleagris gallopavo	81.20	2.00e-177	615.00
IUUC-Mvi-060237	Microbotryum violaceum	31.15	5.00e-44	172.00
IUUC-Mmr-061270	Microcebus murinus	92.70	0.00e+00	744.00
IUUC-Mdo-062965	Monodelphis domestica	86.90	0.00e+00	664.00
IUUC-Mmu-064081	Mus musculus	94.95	0.00e+00	761.00
IUUC-Mac-065236	Musa acuminata	33.43	3.00e-56	211.00
IUUC-Mpu-066355	Mustela putorius furo	97.47	0.00e+00	766.00
IUUC-Mlu-067630	Myotis lucifugus	96.10	0.00e+00	750.00
IUUC-Nle-069701	Nomascus leucogenys	100.00	0.00e+00	766.00
IUUC-Opr-070337	Ochotona princeps	90.34	0.00e+00	691.00
IUUC-Ont-072614	Oreochromis niloticus	69.71	5.00e-148	517.00
IUUC-Ocu-073912	Oryctolagus cuniculus	94.04	0.00e+00	748.00
IUUC-Oba-075195	Oryza barthii	32.44	4.00e-54	204.00
IUUC-Obr-076059	Oryza brachyantha	31.90	2.00e-55	209.00
IUUC-Ogl-077318	Oryza glaberrima	32.18	4.00e-56	211.00
IUUC-Ogu-078579	Oryza glumaepatula	32.05	5.00e-54	204.00
IUUC-Oin-079340	Oryza indica	32.18	4.00e-56	211.00
IUUC-Olo-080813	Oryza longistaminata	32.64	2.00e-54	206.00
IUUC-Ome-081420	Oryza meridionalis	33.04	2.00e-54	206.00
IUUC-Oni-082650	Oryza nivara	32.44	4.00e-54	204.00
IUUC-Opu-083832	Oryza punctata	33.04	8.00e-56	210.00
IUUC-Oru-084207	Oryza rufipogon	32.44	4.00e-54	204.00
IUUC-Osa-085708	Oryza sativa	32.18	4.00e-56	211.00
IUUC-Ola-087164	Oryzias latipes	65.25	3.00e-148	518.00
IUUC-Olu-087824	Ostreococcus lucimarinus	37.60	8.00e-51	194.00
IUUC-Oga-088864	Otolemur garnettii	94.04	0.00e+00	751.00
IUUC-Oar-090115	Ovis aries	98.62	0.00e+00	755.00
IUUC-Ptr-091398	Pan troglodytes	99.77	0.00e+00	765.00
IUUC-Pan-092002	Papio anubis	99.08	0.00e+00	756.00
IUUC-Psi-093979	Pelodiscus sinensis	86.90	1.00e-88	318.00
IUUC-Pma-094618	Petromyzon marinus	61.11	2.00e-128	452.00
IUUC-Ppa-095351	Physcomitrella patens	37.71	1.00e-66	246.00
IUUC-Pfo-097078	Poecilia formosa	72.57	2.00e-150	525.00
IUUC-Pop-099140	Populus trichocarpa	35.53	4.00e-58	218.00
IUUC-Pca-101072	Procavia capensis	91.01	0.00e+00	708.00
IUUC-Ppe-101979	Prunus persica	36.34	6.00e-59	221.00
IUUC-Pva-102400	Pteropus vampyrus	88.97	0.00e+00	677.00
IUUC-Pgr-103362	Puccinia graminis	29.06	1.00e-43	170.00
IUUC-Ptt-103756	Puccinia triticina	31.93	1.00e-32	134.00
IUUC-Rno-105672	Rattus norvegicus	97.93	0.00e+00	770.00
IUUC-Sja-107693	Schizosaccharomyces japonicus	29.36	3.00e-44	172.00
IUUC-Spo-108208	Schizosaccharomyces pombe	29.66	2.00e-47	182.00
IUUC-Smo-109168	Selaginella moellendorffii	34.99	1.00e-57	216.00
IUUC-Sit-109978	Setaria italica	33.05	5.00e-56	211.00
IUUC-Sly-111316	Solanum lycopersicum	36.00	8.00e-60	224.00
IUUC-Stu-111956	Solanum tuberosum	37.32	5.00e-62	231.00
IUUC-Sbi-114189	Sorghum bicolor	33.05	1.00e-53	203.00
IUUC-Sre-115029	Sporisorium reilianum	33.14	5.00e-41	161.00
IUUC-Ssc-116045	Sus scrofa	87.78	2.00e-167	581.00
IUUC-Tgu-117514	Taeniopygia guttata	81.54	2.00e-176	611.00
IUUC-Tru-117851	Takifugu rubripes	67.14	5.00e-142	497.00
IUUC-Tsy-119140	Tarsius syrichta	90.57	0.00e+00	693.00
IUUC-Tni-120248	Tetraodon nigroviridis	67.71	2.00e-142	498.00
IUUC-Tca-121686	Theobroma cacao	32.59	2.00e-55	209.00
IUUC-Tae-123968	Triticum aestivum	34.96	4.00e-59	221.00
IUUC-Tur-126174	Triticum urartu	35.21	4.00e-57	214.00
IUUC-Tme-127079	Tuber melanosporum	27.92	2.00e-13	70.50
IUUC-Tbe-127476	Tupaia belangeri	98.07	5.00e-107	380.00
IUUC-Ttr-128182	Tursiops truncatus	97.93	0.00e+00	768.00
IUUC-Uma-129624	Ustilago maydis	32.55	5.00e-44	172.00
IUUC-Vpa-130605	Vicugna pacos	90.84	1.00e-173	602.00
IUUC-Vvi-131319	Vitis vinifera	34.01	6.00e-57	214.00
IUUC-Xtr-132193	Xenopus tropicalis	71.57	2.00e-165	574.00
IUUC-Xma-133880	Xiphophorus maculatus	71.71	4.00e-150	524.00
IUUC-Yli-134520	Yarrowia lipolytica	28.69	1.00e-26	114.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence