iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-116401

Ensembl Protein ID

ENSSSCP00000022923.1

UniProt Accession

I3LFT1; I3LFT1_PIG

Genbank Protein ID

ENSSSCP00000022923

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

FP312781

Gene Name

RFFL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000026646.1	ENSSSCT00000027235.1	ENSSSCP00000022923.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	90.63	0.00e+00	685.00	IUUC-Hsa-045798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sus scrofa

Protein Sequence
(Fasta)

MSMLTAWPTK ENFIMWATCC NWFCLDGQPE EAPPPQGART QAYSNPGYSS FPSPTGSEPS 60
CKACGAHFAS MSRKQTCLDC KKNFCTTCSS QVGTGPRLCL LCQRFRATAF QREELMKMKV 120

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Nucleotide Sequence
(Fasta)

ATGTCCATGC TGACTGCTTG GCCTACCAAG GAAAGCACGT CTTAACTGTA TCACTGCAGC 60
CCCCCGGCAT TTTAGTGGAC GCCCTCAAAA CCTTTCATTT ATTCTGACAT TTGAGAGATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0002947--C:tumor necrosis factor receptor superfamily complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000777	Aegilops tauschii	33.33	3.00e-07	50.80
IUUC-Aml-001630	Ailuropoda melanoleuca	89.34	0.00e+00	644.00
IUUC-Apl-004124	Anas platyrhynchos	65.75	2.00e-121	428.00
IUUC-Aca-005050	Anolis carolinensis	34.97	2.00e-24	105.00
IUUC-Aly-005548	Arabidopsis lyrata	47.06	2.00e-08	54.70
IUUC-Ath-006731	Arabidopsis thaliana	34.33	5.00e-07	49.70
IUUC-Ame-011616	Astyanax mexicanus	57.65	1.00e-104	372.00
IUUC-Bta-012374	Bos taurus	88.95	0.00e+00	658.00
IUUC-Cja-019780	Callithrix jacchus	87.91	0.00e+00	648.00
IUUC-Cfa-021252	Canis familiaris	91.53	0.00e+00	646.00
IUUC-Cpo-022047	Cavia porcellus	88.25	0.00e+00	647.00
IUUC-Csa-023161	Chlorocebus sabaeus	90.36	0.00e+00	684.00
IUUC-Cho-024316	Choloepus hoffmanni	89.77	1.00e-154	538.00
IUUC-Dre-028596	Danio rerio	55.37	7.00e-109	386.00
IUUC-Dno-029333	Dasypus novemcinctus	92.29	0.00e+00	665.00
IUUC-Dor-030596	Dipodomys ordii	40.62	9.00e-70	256.00
IUUC-Ete-033163	Echinops telfairi	84.57	1.00e-165	575.00
IUUC-Eca-033994	Equus caballus	92.08	0.00e+00	675.00
IUUC-Eeu-035162	Erinaceus europaeus	84.33	1.00e-127	449.00
IUUC-Fca-036418	Felis catus	90.71	0.00e+00	692.00
IUUC-Fal-037427	Ficedula albicollis	67.03	4.00e-134	471.00
IUUC-Gga-041053	Gallus gallus	68.32	2.00e-133	468.00
IUUC-Gac-042281	Gasterosteus aculeatus	45.40	9.00e-74	270.00
IUUC-Ggo-045436	Gorilla gorilla	90.63	0.00e+00	685.00
IUUC-Hsa-045798	Homo sapiens	90.63	0.00e+00	685.00
IUUC-Itr-048077	Ictidomys tridecemlineatus	88.25	0.00e+00	629.00
IUUC-Lch-050639	Latimeria chalumnae	61.43	7.00e-123	433.00
IUUC-Loc-052099	Lepisosteus oculatus	44.85	5.00e-77	281.00
IUUC-Laf-053355	Loxodonta africana	86.18	2.00e-176	610.00
IUUC-Mcc-055222	Macaca mulatta	90.08	0.00e+00	648.00
IUUC-Meu-056692	Macropus eugenii	76.58	7.00e-156	542.00
IUUC-Mga-059298	Meleagris gallopavo	67.95	5.00e-134	470.00
IUUC-Mmr-061792	Microcebus murinus	89.26	0.00e+00	643.00
IUUC-Mdo-062986	Monodelphis domestica	79.08	2.00e-165	575.00
IUUC-Mmu-063356	Mus musculus	87.77	0.00e+00	642.00
IUUC-Mac-064492	Musa acuminata	37.14	3.00e-07	50.40
IUUC-Mpu-066273	Mustela putorius furo	90.98	0.00e+00	693.00
IUUC-Mlu-066953	Myotis lucifugus	91.26	0.00e+00	685.00
IUUC-Nle-070075	Nomascus leucogenys	88.86	0.00e+00	686.00
IUUC-Opr-070838	Ochotona princeps	88.98	0.00e+00	645.00
IUUC-Ont-071967	Oreochromis niloticus	73.43	4.00e-55	207.00
IUUC-Oan-073504	Ornithorhynchus anatinus	41.87	3.00e-57	214.00
IUUC-Ocu-074807	Oryctolagus cuniculus	89.89	0.00e+00	679.00
IUUC-Oba-075828	Oryza barthii	41.51	1.00e-07	52.40
IUUC-Olo-080815	Oryza longistaminata	40.00	3.00e-06	47.80
IUUC-Ola-086903	Oryzias latipes	69.13	9.00e-56	210.00
IUUC-Oga-088536	Otolemur garnettii	87.88	2.00e-178	617.00
IUUC-Oar-089838	Ovis aries	88.68	0.00e+00	644.00
IUUC-Ptr-090962	Pan troglodytes	90.63	0.00e+00	685.00
IUUC-Pan-092853	Papio anubis	89.81	0.00e+00	681.00
IUUC-Psi-093164	Pelodiscus sinensis	69.32	7.00e-126	443.00
IUUC-Pma-094104	Petromyzon marinus	44.55	5.00e-58	218.00
IUUC-Pno-094968	Phaeosphaeria nodorum	38.78	6.00e-09	57.40
IUUC-Pab-098304	Pongo abelii	89.40	0.00e+00	687.00
IUUC-Pop-099791	Populus trichocarpa	33.77	8.00e-08	52.40
IUUC-Pca-100316	Procavia capensis	89.26	2.00e-179	621.00
IUUC-Ppe-101490	Prunus persica	36.59	1.00e-08	54.70
IUUC-Pva-102612	Pteropus vampyrus	76.86	1.00e-154	538.00
IUUC-Rno-105449	Rattus norvegicus	88.15	0.00e+00	633.00
IUUC-Sce-106206	Saccharomyces cerevisiae	43.59	3.80e-01	30.40
IUUC-Sha-107578	Sarcophilus harrisii	78.63	1.00e-154	538.00
IUUC-Sit-110649	Setaria italica	37.14	1.00e-08	52.00
IUUC-Sar-113638	Sorex araneus	88.15	3.00e-179	620.00
IUUC-Tgu-117252	Taeniopygia guttata	46.61	4.00e-73	268.00
IUUC-Tru-118765	Takifugu rubripes	50.41	1.00e-83	302.00
IUUC-Tsy-118850	Tarsius syrichta	87.46	5.00e-152	529.00
IUUC-Tni-119741	Tetraodon nigroviridis	41.98	2.00e-67	248.00
IUUC-Tae-124586	Triticum aestivum	38.18	3.00e-07	49.70
IUUC-Tbe-128086	Tupaia belangeri	81.82	3.00e-174	603.00
IUUC-Ttr-128249	Tursiops truncatus	73.55	6.00e-146	509.00
IUUC-Vpa-130816	Vicugna pacos	89.53	1.00e-41	162.00
IUUC-Xtr-132262	Xenopus tropicalis	46.45	2.00e-68	252.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence