iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118655

UUCD1 version

UUC-TaR-00879

Ensembl Protein ID

ENSTRUP00000040807.1

UniProt Accession

H2UV32; H2UV32_TAKRU

Protein Name

Uncharacterized protein

Gene Name

klhl11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000015960.1	ENSTRUT00000040949.1	ENSTRUP00000040807.1
ENSTRUG00000015960.1	ENSTRUT00000040950.1	ENSTRUP00000040808.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	7.30e-11	43.5	70	149
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.80e-10	39.9	183	214

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvv........ggeeffahkivLaasSsvFyalflmeleesksklmveikd......vqpevfrallkFlYtgklde 67
           +Dv+lv         +  e+fah++vLaa+ ++F  l+ ++++es  +++ve+k+       +p+ ++ +++++Ytg+++ 
   Q: 70   CDVTLVFsgvangsvQSCEVFAHRSVLAAATDYFTPLLGGQFSESL-SGRVEMKEwsselgPDPDTVEGVIQYMYTGEIRV 149
           6777776666666658899**************************9.*******6667899****************9975 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           l Nc+++ ++A++y++++L+++a d+i ++F+
   Q: 183  LTNCMAVHSLAHMYTLDQLALRAADMIRRNFH 214
           58*****************************8 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

FPPLVTSDAR SRMAAAAPNP EDTGRSSAPP TPSALTGDGD AEEAEDFTSS SHCSELSRRQ 60
NEQRKEGLFC DVTLVFSGVA NGSVQSCEVF AHRSVLAAAT DYFTPLLGGQ FSESLSGRVE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCCCTCCTC TGGTCACATC CGACGCCCGC AGCAGGATGG CAGCGGCGGC CCCGAACCCG 60
GAGGACACAG GCAGGAGCAG CGCCCCCCCG ACCCCCAGCG CACTTACGGG AGATGGGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030162--P:regulation of proteolysis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002239	Ailuropoda melanoleuca	73.91	0.00e+00	1008.00
IUUC-Apl-003928	Anas platyrhynchos	76.92	0.00e+00	932.00
IUUC-Aca-004801	Anolis carolinensis	74.54	0.00e+00	980.00
IUUC-Ame-010943	Astyanax mexicanus	90.54	0.00e+00	1052.00
IUUC-Bta-012341	Bos taurus	80.36	9.00e-81	291.00
IUUC-Bci-013778	Botrytis cinerea	24.47	1.00e-05	43.50
IUUC-Cja-019924	Callithrix jacchus	75.26	0.00e+00	1040.00
IUUC-Cfa-021076	Canis familiaris	75.26	0.00e+00	1041.00
IUUC-Cpo-022193	Cavia porcellus	75.66	0.00e+00	1006.00
IUUC-Csa-023614	Chlorocebus sabaeus	75.26	0.00e+00	1038.00
IUUC-Cho-024806	Choloepus hoffmanni	64.05	0.00e+00	683.00
IUUC-Dre-028622	Danio rerio	86.36	0.00e+00	1176.00
IUUC-Dno-029965	Dasypus novemcinctus	73.60	0.00e+00	998.00
IUUC-Dor-030136	Dipodomys ordii	76.09	0.00e+00	859.00
IUUC-Eca-034191	Equus caballus	75.23	0.00e+00	1030.00
IUUC-Eeu-034746	Erinaceus europaeus	74.06	0.00e+00	1025.00
IUUC-Fca-035702	Felis catus	69.91	0.00e+00	928.00
IUUC-Fal-037360	Ficedula albicollis	79.47	0.00e+00	955.00
IUUC-Gmo-038582	Gadus morhua	91.18	0.00e+00	1231.00
IUUC-Gga-040375	Gallus gallus	75.97	0.00e+00	1021.00
IUUC-Gac-042523	Gasterosteus aculeatus	91.82	0.00e+00	1221.00
IUUC-Ggo-045632	Gorilla gorilla	76.56	0.00e+00	863.00
IUUC-Hsa-046817	Homo sapiens	75.26	0.00e+00	1039.00
IUUC-Itr-048433	Ictidomys tridecemlineatus	75.11	0.00e+00	1038.00
IUUC-Lch-049985	Latimeria chalumnae	83.88	0.00e+00	1085.00
IUUC-Loc-052594	Lepisosteus oculatus	86.30	0.00e+00	1165.00
IUUC-Laf-054357	Loxodonta africana	75.26	0.00e+00	1042.00
IUUC-Mcc-055454	Macaca mulatta	75.73	0.00e+00	1037.00
IUUC-Meu-056012	Macropus eugenii	73.29	3.00e-132	464.00
IUUC-Mla-059046	Melampsora laricipopulina	31.48	6.60e-01	27.70
IUUC-Mga-060048	Meleagris gallopavo	77.44	0.00e+00	787.00
IUUC-Mdo-062082	Monodelphis domestica	77.13	0.00e+00	1063.00
IUUC-Mmu-063119	Mus musculus	75.61	0.00e+00	1036.00
IUUC-Mpu-066511	Mustela putorius furo	75.41	0.00e+00	1041.00
IUUC-Mlu-067301	Myotis lucifugus	76.60	0.00e+00	1030.00
IUUC-Nle-069912	Nomascus leucogenys	75.26	0.00e+00	1039.00
IUUC-Opr-070762	Ochotona princeps	74.88	0.00e+00	645.00
IUUC-Ont-071916	Oreochromis niloticus	91.64	0.00e+00	1224.00
IUUC-Oan-072932	Ornithorhynchus anatinus	70.45	0.00e+00	746.00
IUUC-Ocu-074172	Oryctolagus cuniculus	76.58	0.00e+00	854.00
IUUC-Ola-086483	Oryzias latipes	90.20	0.00e+00	1207.00
IUUC-Oga-088112	Otolemur garnettii	74.62	0.00e+00	1004.00
IUUC-Oar-090129	Ovis aries	75.26	0.00e+00	1040.00
IUUC-Ptr-090571	Pan troglodytes	76.47	0.00e+00	860.00
IUUC-Pan-092073	Papio anubis	75.26	0.00e+00	1039.00
IUUC-Psi-093836	Pelodiscus sinensis	75.42	0.00e+00	947.00
IUUC-Pfo-096477	Poecilia formosa	92.74	0.00e+00	1220.00
IUUC-Pab-098473	Pongo abelii	75.26	0.00e+00	1039.00
IUUC-Pca-100239	Procavia capensis	73.77	5.00e-175	607.00
IUUC-Rno-104859	Rattus norvegicus	75.91	0.00e+00	1040.00
IUUC-Sha-106746	Sarcophilus harrisii	78.05	0.00e+00	1064.00
IUUC-Tgu-117183	Taeniopygia guttata	75.65	0.00e+00	1024.00
IUUC-Tsy-119430	Tarsius syrichta	76.24	0.00e+00	1032.00
IUUC-Tni-119698	Tetraodon nigroviridis	96.30	0.00e+00	1132.00
IUUC-Vpa-130715	Vicugna pacos	74.66	0.00e+00	1026.00
IUUC-Xtr-132276	Xenopus tropicalis	73.59	0.00e+00	928.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence