iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-089087

Ensembl Protein ID

ENSOGAP00000004737.2

UniProt Accession

H0WRR9; H0WRR9_OTOGA

Genbank Protein ID

ENSOGAP00000004737

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03040876

Gene Name

HGS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000005291.2	ENSOGAT00000005298.2	ENSOGAP00000004737.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UIM	87.48	0.00e+00	1056.00	IUUC-Bta-012506
UBD/Alpha-Helix/UIM	47.04	1.00e-66	251.00	IUUC-Dme-031952
UBD/Alpha-Helix/DUIM	88.67	0.00e+00	1099.00	IUUC-Hsa-046009
UBD/Alpha-Helix/VHS	88.67	0.00e+00	1099.00	IUUC-Hsa-046009
UBD/Alpha-Helix/UIM	87.66	0.00e+00	1092.00	IUUC-Mmu-063952
UBD/Alpha-Helix/VHS	88.55	0.00e+00	1089.00	IUUC-Rno-105125
UBD/Alpha-Helix/UIM	29.19	2.00e-22	102.00	IUUC-Sce-106192
UBD/Alpha-Helix/UIM	35.71	7.00e-34	140.00	IUUC-Spo-108220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MGRGSGTFER LLADFSPSSL LIPWLFFSLL LLILILRAKY AVNSIKKKVN DKNPHVALYA 60
LEVMESVVKN CGQTVHDEVA NKQTMEELKD LLKRQVEVNV RNKILYLIQA WAHAFRNEPK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGAGAG GCAGCGGCAC CTTCGAGCGT CTCCTAGGTA ACGCGCCCCC GCCTGCTGGC 60
TGCGGCCAGC GTCCTCCCTG CTCCCCCTGC CCGGCGCTGA GTCAGCGCTG TCCCGCGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008942--ENTH_VHS
IPR024641--HRS_helical
IPR017073--Ubi-bd_Hrs_VPS27
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF12210--Hrs_helical
PF00790--VHS

SMART

SM00064--FYVE
SM00288--VHS

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0016021--C:integral component of membrane
GO:0005764--C:lysosome
GO:0046872--F:metal ion binding
GO:0010324--P:membrane invagination
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:1903543--P:positive regulation of exosomal secretion
GO:0010628--P:positive regulation of gene expression
GO:0072657--P:protein localization to membrane
GO:0006622--P:protein targeting to lysosome
GO:0043405--P:regulation of MAP kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001518	Ailuropoda melanoleuca	86.19	0.00e+00	923.00
IUUC-Apl-003662	Anas platyrhynchos	82.42	0.00e+00	974.00
IUUC-Aca-004940	Anolis carolinensis	78.74	0.00e+00	1068.00
IUUC-Ago-007931	Ashbya gossypii	31.18	8.00e-25	108.00
IUUC-Acl-008274	Aspergillus clavatus	30.54	9.00e-35	141.00
IUUC-Afl-008521	Aspergillus flavus	32.64	9.00e-37	148.00
IUUC-Afu-008774	Aspergillus fumigatus	31.84	1.00e-35	144.00
IUUC-Ani-009445	Aspergillus nidulans	32.78	4.00e-37	149.00
IUUC-Ang-009863	Aspergillus niger	32.22	3.00e-37	149.00
IUUC-Ate-010444	Aspergillus terreus	34.71	4.00e-38	152.00
IUUC-Ame-011111	Astyanax mexicanus	73.94	0.00e+00	867.00
IUUC-Bgr-012087	Blumeria graminis	30.90	3.00e-39	156.00
IUUC-Bta-012506	Bos taurus	87.06	0.00e+00	1080.00
IUUC-Bci-013782	Botrytis cinerea	30.84	5.00e-39	156.00
IUUC-Cel-018493	Caenorhabditis elegans	50.00	7.00e-59	221.00
IUUC-Cja-019998	Callithrix jacchus	86.26	0.00e+00	1034.00
IUUC-Cfa-020615	Canis familiaris	83.67	0.00e+00	1001.00
IUUC-Cpo-022019	Cavia porcellus	87.43	0.00e+00	1145.00
IUUC-Csa-023596	Chlorocebus sabaeus	88.82	0.00e+00	1026.00
IUUC-Cin-025488	Ciona intestinalis	45.44	4.00e-114	405.00
IUUC-Csv-025802	Ciona savignyi	49.30	6.00e-106	377.00
IUUC-Cgl-026560	Colletotrichum gloeosporioides	33.12	1.00e-36	148.00
IUUC-Cne-026847	Cryptococcus neoformans	31.30	1.00e-32	134.00
IUUC-Dre-028353	Danio rerio	73.95	0.00e+00	849.00
IUUC-Dno-029005	Dasypus novemcinctus	82.26	0.00e+00	1060.00
IUUC-Dor-030280	Dipodomys ordii	86.49	0.00e+00	1084.00
IUUC-Dse-031238	Dothistroma septosporum	38.71	1.00e-38	154.00
IUUC-Dme-031952	Drosophila melanogaster	47.04	2.00e-67	250.00
IUUC-Ete-032235	Echinops telfairi	84.62	6.00e-111	395.00
IUUC-Eca-033873	Equus caballus	90.39	0.00e+00	1090.00
IUUC-Eeu-034652	Erinaceus europaeus	82.78	9.00e-85	308.00
IUUC-Fca-036563	Felis catus	85.79	0.00e+00	1055.00
IUUC-Fal-036649	Ficedula albicollis	82.89	0.00e+00	1013.00
IUUC-Fox-037962	Fusarium oxysporum	32.77	2.00e-35	144.00
IUUC-Fso-038396	Fusarium solani	33.06	7.00e-36	145.00
IUUC-Gmo-039510	Gadus morhua	70.30	0.00e+00	874.00
IUUC-Ggr-039938	Gaeumannomyces graminis	32.28	2.00e-34	140.00
IUUC-Gga-040201	Gallus gallus	78.39	0.00e+00	1025.00
IUUC-Gac-041459	Gasterosteus aculeatus	70.16	0.00e+00	897.00
IUUC-Ggo-044573	Gorilla gorilla	89.20	0.00e+00	1121.00
IUUC-Hsa-046009	Homo sapiens	88.82	0.00e+00	1159.00
IUUC-Itr-049065	Ictidomys tridecemlineatus	89.07	0.00e+00	1182.00
IUUC-Kpa-049327	Komagataella pastoris	30.56	2.00e-26	114.00
IUUC-Lch-049944	Latimeria chalumnae	76.29	3.00e-156	544.00
IUUC-Loc-051850	Lepisosteus oculatus	75.10	0.00e+00	947.00
IUUC-Lma-053252	Leptosphaeria maculans	35.11	8.00e-37	149.00
IUUC-Laf-053346	Loxodonta africana	79.26	0.00e+00	957.00
IUUC-Mcc-055789	Macaca mulatta	89.32	0.00e+00	1090.00
IUUC-Meu-056329	Macropus eugenii	70.70	4.00e-156	545.00
IUUC-Mor-057205	Magnaporthe oryzae	33.33	3.00e-35	143.00
IUUC-Mpo-057295	Magnaporthe poae	32.28	2.00e-36	147.00
IUUC-Mla-058849	Melampsora laricipopulina	32.79	7.00e-28	119.00
IUUC-Mga-059361	Meleagris gallopavo	80.13	0.00e+00	975.00
IUUC-Mvi-060561	Microbotryum violaceum	32.75	1.00e-34	140.00
IUUC-Mmr-061122	Microcebus murinus	91.40	0.00e+00	966.00
IUUC-Mdo-062171	Monodelphis domestica	85.02	0.00e+00	1105.00
IUUC-Mmu-063952	Mus musculus	87.40	0.00e+00	1194.00
IUUC-Mpu-065852	Mustela putorius furo	84.91	0.00e+00	1009.00
IUUC-Mlu-066996	Myotis lucifugus	79.96	7.00e-138	483.00
IUUC-Nfi-068539	Neosartorya fischeri	31.84	6.00e-36	145.00
IUUC-Ncr-068726	Neurospora crassa	39.56	1.00e-35	144.00
IUUC-Nle-070148	Nomascus leucogenys	83.68	0.00e+00	994.00
IUUC-Opr-070833	Ochotona princeps	72.35	0.00e+00	790.00
IUUC-Ont-071261	Oreochromis niloticus	73.58	0.00e+00	891.00
IUUC-Oan-073684	Ornithorhynchus anatinus	66.82	4.00e-141	494.00
IUUC-Ocu-074133	Oryctolagus cuniculus	33.58	1.00e-15	78.20
IUUC-Ola-087570	Oryzias latipes	70.26	0.00e+00	894.00
IUUC-Oar-089534	Ovis aries	87.06	0.00e+00	1085.00
IUUC-Ptr-091654	Pan troglodytes	83.55	0.00e+00	1006.00
IUUC-Pan-092652	Papio anubis	88.95	0.00e+00	1097.00
IUUC-Pno-095125	Phaeosphaeria nodorum	38.62	2.00e-37	150.00
IUUC-Pfo-096757	Poecilia formosa	72.40	0.00e+00	865.00
IUUC-Pab-097788	Pongo abelii	87.82	0.00e+00	753.00
IUUC-Pca-100145	Procavia capensis	75.84	0.00e+00	866.00
IUUC-Pva-102965	Pteropus vampyrus	82.91	0.00e+00	1026.00
IUUC-Pgr-103609	Puccinia graminis	34.01	2.00e-30	126.00
IUUC-Ptt-103865	Puccinia triticina	34.97	3.00e-31	130.00
IUUC-Pte-104095	Pyrenophora teres	35.48	2.00e-36	147.00
IUUC-Pyt-104668	Pyrenophora triticirepentis	35.64	2.00e-36	147.00
IUUC-Rno-105125	Rattus norvegicus	88.14	0.00e+00	1108.00
IUUC-Sce-106192	Saccharomyces cerevisiae	29.19	1.00e-23	105.00
IUUC-Sha-107066	Sarcophilus harrisii	85.29	0.00e+00	1073.00
IUUC-Sja-107931	Schizosaccharomyces japonicus	33.44	3.00e-37	150.00
IUUC-Spo-108220	Schizosaccharomyces pombe	32.91	1.00e-34	141.00
IUUC-Smo-109055	Selaginella moellendorffii	43.75	2.00e-12	68.20
IUUC-Stu-112464	Solanum tuberosum	45.31	8.00e-14	73.20
IUUC-Sar-113393	Sorex araneus	89.57	5.00e-89	322.00
IUUC-Sre-114986	Sporisorium reilianum	38.80	4.00e-37	150.00
IUUC-Tgu-117505	Taeniopygia guttata	81.66	0.00e+00	987.00
IUUC-Tru-118494	Takifugu rubripes	73.81	0.00e+00	925.00
IUUC-Tsy-119626	Tarsius syrichta	97.80	2.00e-48	187.00
IUUC-Tni-120174	Tetraodon nigroviridis	70.48	0.00e+00	923.00
IUUC-Tre-122191	Trichoderma reesei	32.79	5.00e-36	145.00
IUUC-Tvi-122318	Trichoderma virens	32.68	2.00e-37	150.00
IUUC-Tme-126914	Tuber melanosporum	35.25	3.00e-40	159.00
IUUC-Ttr-129095	Tursiops truncatus	87.87	0.00e+00	1126.00
IUUC-Uma-129475	Ustilago maydis	37.50	3.00e-34	140.00
IUUC-Vda-129908	Verticillium dahliae	32.08	2.00e-31	130.00
IUUC-Xtr-131900	Xenopus tropicalis	72.64	0.00e+00	958.00
IUUC-Xma-133124	Xiphophorus maculatus	72.32	0.00e+00	901.00
IUUC-Yli-134682	Yarrowia lipolytica	35.29	7.00e-27	115.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence