iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-117505

Ensembl Protein ID

ENSTGUP00000003542.1

UniProt Accession

H0YZ10; H0YZ10_TAEGU

Genbank Protein ID

ENSTGUP00000003542

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01037500

Gene Name

HGS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000003410.1	ENSTGUT00000003578.1	ENSTGUP00000003542.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/VHS	3.70e-51	172.4	3	131

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/VHS

   S: 1    atselvtsedwelileicdliqetkegakdalralrkrinnknphvalraLtlLdscvsnCgkkfhvevaskdlleelrellknenepk 89
           ats+l+ ++dwe+il+icd+i++ +++ak+a++a++k++n+knphval+aL++++s+v+nCg+++h+eva+k+++eel+e+lk+++e+ 
   Q: 3    ATSQLLLETDWESILQICDMIRQGDTQAKYAVNAIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKEILKRQVETS 91
           799************************************************************************************** PP
   S: 90   vieKlkalivsWadelknepalslivaliktlkeeGlefp 129
           v+ K+++li++Wa++++nep++++++++++ +k eG++fp
   Q: 92   VRSKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFP 131
           ***************************************8 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

DKATSQLLLE TDWESILQIC DMIRQGDTQA KYAVNAIKKK VNDKNPHVAL YALEVMESVV 60
KNCGQTVHDE VANKQTMEEL KEILKRQVET SVRSKILYLI QAWAHAFRNE PKYKVVQDTY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATAAGGCCA CGAGCCAGCT CCTGCTGGAG ACAGACTGGG AATCCATCCT GCAGATCTGC 60
GACATGATCC GTCAGGGAGA CACCCAGTAA GTGCTCCTGG GCTTTAGGAC GCGCTGTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008942--ENTH_VHS
IPR024641--HRS_helical
IPR017073--Ubi-bd_Hrs_VPS27
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF12210--Hrs_helical
PF00790--VHS

SMART

SM00064--FYVE
SM00288--VHS

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0005764--C:lysosome
GO:0046872--F:metal ion binding
GO:0010324--P:membrane invagination
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:1903543--P:positive regulation of exosomal secretion
GO:0010628--P:positive regulation of gene expression
GO:0072657--P:protein localization to membrane
GO:0006622--P:protein targeting to lysosome
GO:0043405--P:regulation of MAP kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001518	Ailuropoda melanoleuca	79.07	0.00e+00	899.00
IUUC-Apl-003662	Anas platyrhynchos	92.12	0.00e+00	1052.00
IUUC-Aca-004940	Anolis carolinensis	86.70	0.00e+00	1182.00
IUUC-Ago-007931	Ashbya gossypii	31.73	4.00e-27	115.00
IUUC-Acl-008274	Aspergillus clavatus	29.74	4.00e-38	152.00
IUUC-Afl-008521	Aspergillus flavus	32.41	4.00e-40	159.00
IUUC-Afu-008774	Aspergillus fumigatus	31.60	2.00e-39	157.00
IUUC-Ani-009445	Aspergillus nidulans	32.94	8.00e-41	161.00
IUUC-Ang-009863	Aspergillus niger	31.97	1.00e-40	161.00
IUUC-Ate-010444	Aspergillus terreus	34.69	1.00e-41	163.00
IUUC-Ame-011111	Astyanax mexicanus	79.92	0.00e+00	931.00
IUUC-Bgr-012087	Blumeria graminis	33.81	2.00e-41	164.00
IUUC-Bta-012506	Bos taurus	84.48	0.00e+00	1067.00
IUUC-Bci-013782	Botrytis cinerea	32.54	1.00e-39	157.00
IUUC-Cel-018493	Caenorhabditis elegans	52.68	4.00e-66	245.00
IUUC-Cja-019998	Callithrix jacchus	79.97	0.00e+00	974.00
IUUC-Cfa-020615	Canis familiaris	80.26	0.00e+00	969.00
IUUC-Cpo-022019	Cavia porcellus	83.49	0.00e+00	1097.00
IUUC-Csa-023596	Chlorocebus sabaeus	81.06	0.00e+00	986.00
IUUC-Cin-025488	Ciona intestinalis	48.49	4.00e-126	445.00
IUUC-Csv-025802	Ciona savignyi	49.91	3.00e-116	411.00
IUUC-Cgl-026560	Colletotrichum gloeosporioides	35.29	3.00e-40	159.00
IUUC-Cne-026847	Cryptococcus neoformans	31.08	4.00e-36	145.00
IUUC-Dre-028353	Danio rerio	78.42	0.00e+00	920.00
IUUC-Dno-029005	Dasypus novemcinctus	78.68	0.00e+00	1026.00
IUUC-Dor-030280	Dipodomys ordii	82.47	0.00e+00	1048.00
IUUC-Dse-031238	Dothistroma septosporum	39.35	5.00e-43	169.00
IUUC-Dme-031952	Drosophila melanogaster	46.20	5.00e-98	351.00
IUUC-Ete-032235	Echinops telfairi	95.19	1.00e-123	436.00
IUUC-Eca-033873	Equus caballus	82.81	0.00e+00	1060.00
IUUC-Eeu-034652	Erinaceus europaeus	95.81	7.00e-98	351.00
IUUC-Fca-036563	Felis catus	80.49	0.00e+00	1009.00
IUUC-Fal-036649	Ficedula albicollis	95.13	0.00e+00	1200.00
IUUC-Fox-037962	Fusarium oxysporum	32.46	3.00e-38	153.00
IUUC-Fso-038396	Fusarium solani	33.09	2.00e-38	154.00
IUUC-Gmo-039510	Gadus morhua	75.58	0.00e+00	917.00
IUUC-Ggr-039938	Gaeumannomyces graminis	32.32	2.00e-37	150.00
IUUC-Gga-040201	Gallus gallus	90.97	0.00e+00	1191.00
IUUC-Gac-041459	Gasterosteus aculeatus	76.03	0.00e+00	934.00
IUUC-Ggo-044573	Gorilla gorilla	82.03	0.00e+00	1047.00
IUUC-Hsa-046009	Homo sapiens	81.64	0.00e+00	1087.00
IUUC-Itr-049065	Ictidomys tridecemlineatus	80.52	0.00e+00	1109.00
IUUC-Kpa-049327	Komagataella pastoris	31.58	4.00e-32	132.00
IUUC-Lch-049944	Latimeria chalumnae	80.22	5.00e-162	563.00
IUUC-Loc-051850	Lepisosteus oculatus	81.07	0.00e+00	1028.00
IUUC-Lma-053252	Leptosphaeria maculans	35.78	1.00e-40	161.00
IUUC-Laf-053346	Loxodonta africana	76.00	0.00e+00	944.00
IUUC-Mcc-055789	Macaca mulatta	83.47	0.00e+00	1044.00
IUUC-Meu-056329	Macropus eugenii	67.10	3.00e-148	518.00
IUUC-Mor-057205	Magnaporthe oryzae	33.69	1.00e-37	151.00
IUUC-Mpo-057295	Magnaporthe poae	32.31	3.00e-39	156.00
IUUC-Mla-058849	Melampsora laricipopulina	32.85	4.00e-31	129.00
IUUC-Mga-059361	Meleagris gallopavo	90.76	0.00e+00	1152.00
IUUC-Mvi-060561	Microbotryum violaceum	36.73	2.00e-36	146.00
IUUC-Mmr-061122	Microcebus murinus	87.32	0.00e+00	929.00
IUUC-Mdo-062171	Monodelphis domestica	85.39	0.00e+00	1120.00
IUUC-Mmu-063952	Mus musculus	81.99	0.00e+00	1136.00
IUUC-Mpu-065852	Mustela putorius furo	81.14	0.00e+00	979.00
IUUC-Mlu-066996	Myotis lucifugus	75.00	3.00e-128	451.00
IUUC-Nfi-068539	Neosartorya fischeri	31.60	9.00e-40	158.00
IUUC-Ncr-068726	Neurospora crassa	38.68	2.00e-38	153.00
IUUC-Nle-070148	Nomascus leucogenys	76.48	0.00e+00	935.00
IUUC-Opr-070833	Ochotona princeps	65.37	6.00e-126	444.00
IUUC-Ont-071261	Oreochromis niloticus	78.79	0.00e+00	945.00
IUUC-Oan-073684	Ornithorhynchus anatinus	71.19	3.00e-153	534.00
IUUC-Ola-087570	Oryzias latipes	74.16	0.00e+00	954.00
IUUC-Oga-089087	Otolemur garnettii	84.18	0.00e+00	981.00
IUUC-Oar-089534	Ovis aries	84.04	0.00e+00	1067.00
IUUC-Ptr-091654	Pan troglodytes	76.95	0.00e+00	944.00
IUUC-Pan-092652	Papio anubis	81.19	0.00e+00	1044.00
IUUC-Pno-095125	Phaeosphaeria nodorum	36.24	7.00e-40	158.00
IUUC-Pfo-096757	Poecilia formosa	78.25	0.00e+00	916.00
IUUC-Pab-097788	Pongo abelii	87.55	0.00e+00	750.00
IUUC-Pca-100145	Procavia capensis	72.79	0.00e+00	830.00
IUUC-Pva-102965	Pteropus vampyrus	80.82	0.00e+00	994.00
IUUC-Pgr-103609	Puccinia graminis	34.18	6.00e-34	138.00
IUUC-Ptt-103865	Puccinia triticina	35.42	2.00e-34	140.00
IUUC-Pte-104095	Pyrenophora teres	34.86	2.00e-39	157.00
IUUC-Pyt-104668	Pyrenophora triticirepentis	35.32	1.00e-39	157.00
IUUC-Rno-105125	Rattus norvegicus	83.47	0.00e+00	1052.00
IUUC-Sce-106192	Saccharomyces cerevisiae	30.10	2.00e-27	116.00
IUUC-Sha-107066	Sarcophilus harrisii	86.48	0.00e+00	1091.00
IUUC-Sja-107931	Schizosaccharomyces japonicus	32.97	5.00e-40	159.00
IUUC-Spo-108220	Schizosaccharomyces pombe	34.26	2.00e-38	153.00
IUUC-Stu-112464	Solanum tuberosum	45.90	2.00e-13	71.20
IUUC-Sar-113393	Sorex araneus	91.58	5.00e-106	378.00
IUUC-Sre-114986	Sporisorium reilianum	39.72	6.00e-42	165.00
IUUC-Tru-118494	Takifugu rubripes	79.03	0.00e+00	991.00
IUUC-Tsy-119626	Tarsius syrichta	97.80	8.00e-49	187.00
IUUC-Tni-120174	Tetraodon nigroviridis	74.14	0.00e+00	982.00
IUUC-Tre-122191	Trichoderma reesei	33.21	1.00e-39	157.00
IUUC-Tvi-122318	Trichoderma virens	32.48	3.00e-39	156.00
IUUC-Tme-126914	Tuber melanosporum	35.40	3.00e-44	172.00
IUUC-Ttr-129095	Tursiops truncatus	84.91	0.00e+00	1088.00
IUUC-Uma-129475	Ustilago maydis	36.74	2.00e-37	150.00
IUUC-Vda-129908	Verticillium dahliae	32.22	3.00e-35	143.00
IUUC-Xtr-131900	Xenopus tropicalis	78.56	0.00e+00	1043.00
IUUC-Xma-133124	Xiphophorus maculatus	73.87	0.00e+00	951.00
IUUC-Yli-134682	Yarrowia lipolytica	33.21	6.00e-33	135.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence