iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033683

UUCD1 version

UUC-EqC-00313

Ensembl Protein ID

ENSECAP00000013767.1

UniProt Accession

F6V134; F6V134_HORSE

Protein Name

Uncharacterized protein

Gene Name

AMFR

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000015773.1	ENSECAT00000017000.1	ENSECAP00000013767.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/CUE	2.50e-11	43.5	453	494

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/CUE

   S: 1    dletaleqLkeiFPnldysviqvvLeantgsleaavnnLLegs 43
           +l+ +++q++e+FP+++y ++ ++L ++t s+e +++n+Leg 
   Q: 453  QLNAMAHQIQEMFPQVPYHLVLQDL-QLTRSVEITTDNILEGR 494
           5889*********************.***************95 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MPLLFLERFP WPSLRTYTGL SGLGLLGTIF RAYRALTQPQ GGAGARRGQN TPMVPALVAD 60
SAGSTGRPRN RNMKQSLLSD LMLFWVLVNT ACCVLMLVAK LIQCIVFGPL RVSERQHLKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCGTTGC TCTTCCTCGA GCGCTTCCCC TGGCCCAGCC TCCGCACCTA CACGGGCCTC 60
AGCGGCCTGG GCCTGCTCGG GACCATCTTC AGGGCCTACC GCGCCCTCAC CCAACCCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003892--CUE
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51140--CUE

Pfam

PF02845--CUE

SMART

SM00546--CUE

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0005794--C:Golgi apparatus
GO:0030176--C:integral component of endoplasmic reticulum membrane
GO:0048471--C:perinuclear region of cytoplasm
GO:0004872--F:receptor activity
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:1990381--F:ubiquitin-specific protease binding
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0032092--P:positive regulation of protein binding
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0051259--P:protein oligomerization
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001300	Ailuropoda melanoleuca	92.81	0.00e+00	972.00
IUUC-Apl-003404	Anas platyrhynchos	85.97	0.00e+00	893.00
IUUC-Aca-004559	Anolis carolinensis	82.49	0.00e+00	824.00
IUUC-Ame-011640	Astyanax mexicanus	70.27	0.00e+00	780.00
IUUC-Bta-012980	Bos taurus	87.17	0.00e+00	1032.00
IUUC-Cel-018598	Caenorhabditis elegans	23.13	6.00e-28	119.00
IUUC-Cja-019577	Callithrix jacchus	88.98	0.00e+00	1068.00
IUUC-Cfa-020793	Canis familiaris	93.76	0.00e+00	997.00
IUUC-Cpo-022387	Cavia porcellus	88.66	0.00e+00	1045.00
IUUC-Csa-023168	Chlorocebus sabaeus	89.60	0.00e+00	1076.00
IUUC-Cho-024433	Choloepus hoffmanni	94.10	0.00e+00	810.00
IUUC-Cin-025215	Ciona intestinalis	43.63	1.00e-133	470.00
IUUC-Csv-026133	Ciona savignyi	47.89	6.00e-122	431.00
IUUC-Cgl-026735	Colletotrichum gloeosporioides	27.66	4.00e-03	34.30
IUUC-Dre-027594	Danio rerio	68.08	0.00e+00	734.00
IUUC-Dno-029407	Dasypus novemcinctus	94.63	0.00e+00	964.00
IUUC-Dor-030961	Dipodomys ordii	94.63	0.00e+00	991.00
IUUC-Ete-032962	Echinops telfairi	84.97	0.00e+00	811.00
IUUC-Eeu-034515	Erinaceus europaeus	91.85	5.00e-67	248.00
IUUC-Fca-035398	Felis catus	95.50	0.00e+00	963.00
IUUC-Fal-036758	Ficedula albicollis	79.55	0.00e+00	826.00
IUUC-Gmo-039014	Gadus morhua	67.11	0.00e+00	725.00
IUUC-Gga-040575	Gallus gallus	81.37	0.00e+00	958.00
IUUC-Gac-041414	Gasterosteus aculeatus	66.39	0.00e+00	714.00
IUUC-Hsa-046272	Homo sapiens	89.44	0.00e+00	1058.00
IUUC-Itr-047956	Ictidomys tridecemlineatus	92.67	0.00e+00	966.00
IUUC-Lch-050491	Latimeria chalumnae	74.04	0.00e+00	816.00
IUUC-Loc-052758	Lepisosteus oculatus	73.75	0.00e+00	792.00
IUUC-Laf-053452	Loxodonta africana	93.02	0.00e+00	983.00
IUUC-Mcc-055820	Macaca mulatta	94.35	0.00e+00	980.00
IUUC-Meu-056726	Macropus eugenii	80.71	0.00e+00	788.00
IUUC-Mga-059937	Meleagris gallopavo	86.94	0.00e+00	892.00
IUUC-Mmr-060730	Microcebus murinus	88.51	0.00e+00	1025.00
IUUC-Mdo-062771	Monodelphis domestica	85.13	0.00e+00	996.00
IUUC-Mmu-064219	Mus musculus	88.94	0.00e+00	1064.00
IUUC-Mpu-066796	Mustela putorius furo	95.26	0.00e+00	989.00
IUUC-Mlu-068189	Myotis lucifugus	92.32	0.00e+00	962.00
IUUC-Nle-069239	Nomascus leucogenys	88.98	0.00e+00	1038.00
IUUC-Opr-070702	Ochotona princeps	86.45	5.00e-126	444.00
IUUC-Ont-072033	Oreochromis niloticus	68.93	0.00e+00	763.00
IUUC-Oan-073717	Ornithorhynchus anatinus	91.25	0.00e+00	832.00
IUUC-Ocu-074145	Oryctolagus cuniculus	87.42	0.00e+00	1046.00
IUUC-Ola-087152	Oryzias latipes	66.50	0.00e+00	737.00
IUUC-Oga-088486	Otolemur garnettii	92.73	0.00e+00	977.00
IUUC-Oar-089310	Ovis aries	94.81	0.00e+00	1003.00
IUUC-Ptr-090649	Pan troglodytes	94.10	0.00e+00	997.00
IUUC-Pan-091692	Papio anubis	85.56	0.00e+00	994.00
IUUC-Psi-093064	Pelodiscus sinensis	92.71	0.00e+00	736.00
IUUC-Pma-094763	Petromyzon marinus	77.87	3.00e-97	347.00
IUUC-Ppa-095969	Physcomitrella patens	28.66	3.00e-31	130.00
IUUC-Pfo-096810	Poecilia formosa	68.42	0.00e+00	753.00
IUUC-Pab-097859	Pongo abelii	93.99	0.00e+00	978.00
IUUC-Pca-100344	Procavia capensis	88.06	0.00e+00	1011.00
IUUC-Pva-103114	Pteropus vampyrus	65.12	0.00e+00	654.00
IUUC-Rno-105880	Rattus norvegicus	87.21	0.00e+00	1013.00
IUUC-Sha-107015	Sarcophilus harrisii	90.34	0.00e+00	944.00
IUUC-Smo-109664	Selaginella moellendorffii	29.43	1.00e-28	120.00
IUUC-Sar-113397	Sorex araneus	95.69	0.00e+00	724.00
IUUC-Ssc-115988	Sus scrofa	91.35	2.00e-131	461.00
IUUC-Tgu-116717	Taeniopygia guttata	85.92	0.00e+00	874.00
IUUC-Tru-117805	Takifugu rubripes	65.74	0.00e+00	773.00
IUUC-Tsy-119442	Tarsius syrichta	88.01	0.00e+00	897.00
IUUC-Tni-119777	Tetraodon nigroviridis	69.95	1.00e-161	562.00
IUUC-Tbe-127322	Tupaia belangeri	66.27	4.00e-105	375.00
IUUC-Ttr-128181	Tursiops truncatus	94.63	0.00e+00	1004.00
IUUC-Vpa-130483	Vicugna pacos	83.10	0.00e+00	629.00
IUUC-Xtr-132614	Xenopus tropicalis	74.01	0.00e+00	738.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence