iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117905

UUCD1 version

UUC-TaR-00394

Ensembl Protein ID

ENSTRUP00000019298.1

UniProt Accession

H2T3R0; H2T3R0_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000007761.1	ENSTRUT00000019376.1	ENSTRUP00000019298.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-35	120.4	194	232
UBD/Beta-Prp	1.60e-48	166.7	189	392

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllks 38
           Ht+ v++++f  +d  ++++s+Dgt+ +WD+ +g ll+s
   Q: 194  HTNYVSGCSFvnTDMQILTSSGDGTCALWDVESGQLLQS 232
           9**********55588******************99986 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqcleet 132
           +s+  h++ v+ ++f +++  ++t+s D+t  +wd+++g+ +++++gh+++vlsl+f p  +g+ ++sG+ d+ ++vwd+++gq ++  
   Q: 189  KSVAMHTNYVSGCSFVNTDMQILTSSGDGTCALWDVESGQLLQSFHGHTADVLSLDFIPseTGNIFISGGCDKKANVWDMRSGQNIQ-S 276
           577889*************9***************************************9777************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh.tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           +++h + vncv++hp+g+ ++s+s+D t+r++dl+ ++ +   +++       sl+f+ +g+ l +g +d t+++wd+ +g+ v  l g
   Q: 277  FENHVSDVNCVKFHPSGDAFASASDDATCRFYDLRADREVAVYQKDSiIFGASSLDFSLSGRLLFTGYNDYTINVWDVLKGSRVSVLFG 365
           *****************************************996622133557888********************************* PP
   S: 221  htdnvksvrfspnderlvsgssDgsir 247
           h++ +++vr+sp+++ l s+s D ++r
   Q: 366  HENRISRVRVSPDGTALCSASWDSTLR 392
           ***********************9987 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MCDQTFVAAT FGPCDSCANP SPLMNIYIKN EPINYCSFCV EMMACRELQR GETLASLKRE 60
SDTLKKKLEE ERGKLNDVEL HQVAEKVDTL GALSLKTKRV LKGHGNKVLC MDWCKDKRRL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGCGACC AGACGTTTGT GGCGGCCACT TTTGGCCCCT GCGACAGCTG TGCGAACCCG 60
AGTCCACTGA TGAACATCTA CATCAAGAAC GAGCCCATCA ACTACTGCTC GTTCTGCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR002475--Bcl2-like
IPR026298--Blc2_fam
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50062--BCL2_FAMILY
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00452--Bcl-2
PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0042981--P:regulation of apoptotic process
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dre-028432	Danio rerio	81.12	0.00e+00	657.00
IUUC-Loc-052790	Lepisosteus oculatus	72.05	0.00e+00	799.00
IUUC-Ont-071535	Oreochromis niloticus	88.52	0.00e+00	661.00
IUUC-Ola-087428	Oryzias latipes	87.31	0.00e+00	667.00
IUUC-Pma-094140	Petromyzon marinus	69.01	6.00e-87	313.00
IUUC-Pfo-096685	Poecilia formosa	88.01	0.00e+00	670.00
IUUC-Tni-119834	Tetraodon nigroviridis	94.39	0.00e+00	714.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence