iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107499

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01111388

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000018839.1	ENSSHAT00000022440.1	ENSSHAP00000022262.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	3.10e-26	91.4	404	475
E3 adaptor/Cullin RING/DCX/DWD	1.90e-38	129.0	53	88
UBD/Beta-Prp	1.50e-52	178.8	7	217

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           +p+eflCpI+ elM+dPv++++G++y++++Ie w++++++t+P+t+  l +  l+Pn tl+  i++w+e+++
   Q: 404  IPDEFLCPITRELMQDPVIASDGYSYEKEAIENWISKKKRTSPMTNLVLPSLILTPNRTLKMAIDRWLETHQ 475
           8********************************************************************997 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           Ht  v+c++f ++ ++l+s+s Dgt  +W++ tg  
   Q: 53   HTYAVHCCCFsPSgHILASCSTDGTTVLWNTQTGLI 88
           9999*******666999*************999976 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           tl +h ++v +c  f  ++sllat s d+t++++++   +    + l+ h+ +v +++fsp+g il+++s+D+t  +w+ +tg ++ +l
   Q: 7    TLADHGDDV-NCCSF--SSSLLATCSLDKTLRLYSLNGFNElpYSPLKYHTYAVHCCCFSPSGHILASCSTDGTTVLWNTQTGLILAVL 92
           555555555.55788..9******************99777778999****************************************** PP
   S: 91   kghe.dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           ++ + + v+ ++fsp++ +lvsG +d t+  w+++t + ++ + s++dg+    +++p+g+++v+Gs  + + +Wd k+ + l+  +  
   Q: 93   NQPSgSPVRVCRFSPDSTYLVSGAADGTVVSWNMQTHKLFR-CGSVKDGSLVACAFSPNGSIFVTGSSCGDLTVWDDKMRC-LYSEKA- 178
           9765267**********************************.**********************************96655.555555. PP
   S: 179  htdsvyslsfdsng..........kelvsgsldgtvklw 207
           h+  +++ +f+s+           ++++s+++d ++klw
   Q: 179  HDLGITCCDFSSQPisdgehgpqfFRMASCGQDCQIKLW 217
           ***********998999********************** PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MVTLIHTLAD HGDDVNCCSF SSSLLATCSL DKTLRLYSLN GFNELPYSPL KYHTYAVHCC 60
CFSPSGHILA SCSTDGTTVL WNTQTGLILA VLNQPSGSPV RVCRFSPDST YLVSGAADGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGACAC TAATTCATAC ACTAGCAGAT CATGGTGATG ATGTCAACTG CTGTTCCTTT 60
TCTTCTTCCC TTTTGGCTAC TTGCTCCTTG GATAAGACAC TTCGTCTCTA TTCATTAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	84.24	0.00e+00	847.00
IUUC-Apl-003529	Anas platyrhynchos	76.26	0.00e+00	768.00
IUUC-Aca-004257	Anolis carolinensis	71.05	0.00e+00	710.00
IUUC-Ame-011357	Astyanax mexicanus	50.84	8.00e-113	400.00
IUUC-Bta-013032	Bos taurus	81.55	0.00e+00	817.00
IUUC-Cja-018743	Callithrix jacchus	83.19	0.00e+00	832.00
IUUC-Cfa-021197	Canis familiaris	83.82	0.00e+00	849.00
IUUC-Cpo-022279	Cavia porcellus	82.35	0.00e+00	833.00
IUUC-Csa-023954	Chlorocebus sabaeus	84.87	0.00e+00	848.00
IUUC-Cho-025083	Choloepus hoffmanni	67.99	4.00e-146	510.00
IUUC-Cin-025786	Ciona intestinalis	36.09	2.00e-83	302.00
IUUC-Dre-028087	Danio rerio	57.20	5.00e-144	504.00
IUUC-Dno-028919	Dasypus novemcinctus	84.24	0.00e+00	844.00
IUUC-Dor-031112	Dipodomys ordii	80.67	0.00e+00	803.00
IUUC-Ete-032405	Echinops telfairi	81.63	2.00e-170	591.00
IUUC-Eca-033254	Equus caballus	82.77	0.00e+00	830.00
IUUC-Eeu-034545	Erinaceus europaeus	78.78	0.00e+00	770.00
IUUC-Fca-035482	Felis catus	84.66	0.00e+00	845.00
IUUC-Fal-036976	Ficedula albicollis	62.55	3.00e-166	577.00
IUUC-Gmo-039213	Gadus morhua	54.83	4.00e-138	484.00
IUUC-Gga-040561	Gallus gallus	74.63	0.00e+00	751.00
IUUC-Gac-041471	Gasterosteus aculeatus	57.98	1.00e-140	492.00
IUUC-Ggo-045503	Gorilla gorilla	84.24	0.00e+00	845.00
IUUC-Hsa-045910	Homo sapiens	84.66	0.00e+00	849.00
IUUC-Hvu-047757	Hordeum vulgare	46.15	5.00e-19	89.70
IUUC-Itr-048214	Ictidomys tridecemlineatus	81.43	0.00e+00	644.00
IUUC-Loc-052307	Lepisosteus oculatus	59.13	5.00e-170	590.00
IUUC-Laf-053587	Loxodonta africana	82.98	0.00e+00	832.00
IUUC-Mcc-055679	Macaca mulatta	84.66	0.00e+00	847.00
IUUC-Meu-055962	Macropus eugenii	77.31	0.00e+00	704.00
IUUC-Mga-059652	Meleagris gallopavo	74.42	0.00e+00	758.00
IUUC-Mmr-060943	Microcebus murinus	80.96	0.00e+00	810.00
IUUC-Mdo-062592	Monodelphis domestica	91.23	0.00e+00	907.00
IUUC-Mmu-063577	Mus musculus	77.57	0.00e+00	772.00
IUUC-Mpu-066422	Mustela putorius furo	83.61	0.00e+00	840.00
IUUC-Mlu-067250	Myotis lucifugus	82.56	0.00e+00	823.00
IUUC-Nle-069517	Nomascus leucogenys	84.03	0.00e+00	843.00
IUUC-Opr-070776	Ochotona princeps	83.19	0.00e+00	827.00
IUUC-Ont-071821	Oreochromis niloticus	57.11	3.00e-149	521.00
IUUC-Oan-073706	Ornithorhynchus anatinus	85.89	0.00e+00	852.00
IUUC-Ocu-074766	Oryctolagus cuniculus	76.04	0.00e+00	741.00
IUUC-Ola-086531	Oryzias latipes	56.21	2.00e-145	508.00
IUUC-Oga-088388	Otolemur garnettii	82.35	0.00e+00	833.00
IUUC-Oar-089748	Ovis aries	82.18	0.00e+00	816.00
IUUC-Ptr-090616	Pan troglodytes	84.14	0.00e+00	838.00
IUUC-Pan-091769	Papio anubis	85.17	1.00e-176	611.00
IUUC-Psi-093334	Pelodiscus sinensis	79.62	0.00e+00	752.00
IUUC-Pma-094383	Petromyzon marinus	49.12	4.00e-132	464.00
IUUC-Pfo-096801	Poecilia formosa	56.37	2.00e-145	509.00
IUUC-Pab-098139	Pongo abelii	83.29	0.00e+00	679.00
IUUC-Pca-100523	Procavia capensis	70.59	0.00e+00	689.00
IUUC-Pva-102286	Pteropus vampyrus	83.61	0.00e+00	810.00
IUUC-Rno-104831	Rattus norvegicus	78.57	0.00e+00	786.00
IUUC-Sar-113389	Sorex araneus	80.67	0.00e+00	775.00
IUUC-Tgu-116769	Taeniopygia guttata	73.32	0.00e+00	729.00
IUUC-Tru-118774	Takifugu rubripes	53.29	2.00e-136	478.00
IUUC-Tsy-119595	Tarsius syrichta	72.57	5.00e-168	583.00
IUUC-Tni-119850	Tetraodon nigroviridis	56.87	2.00e-146	511.00
IUUC-Tbe-127938	Tupaia belangeri	75.41	1.00e-134	472.00
IUUC-Ttr-128193	Tursiops truncatus	82.55	0.00e+00	695.00
IUUC-Vpa-130275	Vicugna pacos	84.24	0.00e+00	840.00
IUUC-Xtr-131982	Xenopus tropicalis	62.74	3.00e-170	591.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence