iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132325

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01098890

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000031122.1	ENSXETT00000038738.3	ENSXETP00000038738.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	1.00e-48	166.5	91	290

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++Cl+++++eel+ ll+C+h+ C  Cl+qyl+++i+e++ +++ cp  ec e+l++++++++l ++ l+++ye++ll+++++ad++++w
   Q: 91   CPLCLVRQPPEELPELLSCRHRSCLRCLRQYLRIEISESR-VNLRCP--ECAERLSPQHVRAILRDPLLTRKYEEFLLRRCLAADPDCRW 177
           ****************************************.9*****..89*************************************** PP
   S: 91   cpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeek......eeaeskelleanskkCpkCkvyie 172
           cpapdC ++v++  +a  +kl++e+e+c++efC++Ck+ wH++++C+++++++a +   +       ++ +++  ++++k+Cp+C++yi+
   Q: 178  CPAPDCGYAVIAYGCAscPKLTCEREGCQTEFCYHCKHVWHPNQTCDMARQQRAPSLGVRrkhpsgISYGQESGSADDMKSCPRCSAYII 267
           *************999899*********************************99998777788988888999999*************** PP
   S: 173  k..negCnhmtCakCkaefCwlC 193
           k  +++CnhmtCa C++efCwlC
   Q: 268  KmnDGSCNHMTCAVCGCEFCWLC 290
           997889***************** PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MRLRRFRSVR LPTSWFGIFG FPDMTEGSAE PPPCPGARRR RLLLSLPNVF PGRTRAAPEP 60
SVPSPPPSPP PPVSVPPPPS SPGGSDSLIE CPLCLVRQPP EELPELLSCR HRSCLRCLRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGCCTGC GCAGATTCCG CTCGGTCCGG CTACCAACTT CCTGGTTCGG TATCTTCGGG 60
TTCCCTGACA TGACAGAAGG CTCTGCGGAG CCACCGCCCT GCCCCGGGGC TCGGCGTCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0044194--C:cytolytic granule
GO:0016021--C:integral component of membrane
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002183	Ailuropoda melanoleuca	83.22	0.00e+00	693.00
IUUC-Apl-003468	Anas platyrhynchos	89.46	2.00e-179	621.00
IUUC-Aca-004324	Anolis carolinensis	86.49	0.00e+00	751.00
IUUC-Ame-011813	Astyanax mexicanus	68.71	7.00e-175	607.00
IUUC-Bta-013135	Bos taurus	85.13	0.00e+00	743.00
IUUC-Cja-019264	Callithrix jacchus	84.80	0.00e+00	738.00
IUUC-Cpo-022502	Cavia porcellus	88.16	0.00e+00	651.00
IUUC-Cho-025032	Choloepus hoffmanni	75.31	8.00e-159	553.00
IUUC-Dre-028769	Danio rerio	71.19	0.00e+00	649.00
IUUC-Dor-030551	Dipodomys ordii	88.89	1.00e-107	383.00
IUUC-Ete-033008	Echinops telfairi	71.89	3.00e-141	494.00
IUUC-Eca-033267	Equus caballus	88.11	3.00e-172	598.00
IUUC-Fca-035520	Felis catus	88.38	2.00e-172	598.00
IUUC-Gac-041619	Gasterosteus aculeatus	71.70	0.00e+00	646.00
IUUC-Hsa-045958	Homo sapiens	84.98	0.00e+00	746.00
IUUC-Itr-048425	Ictidomys tridecemlineatus	87.98	0.00e+00	642.00
IUUC-Lch-049552	Latimeria chalumnae	84.08	0.00e+00	745.00
IUUC-Loc-051738	Lepisosteus oculatus	75.00	0.00e+00	678.00
IUUC-Meu-055920	Macropus eugenii	88.16	0.00e+00	656.00
IUUC-Mdo-061985	Monodelphis domestica	85.19	0.00e+00	749.00
IUUC-Mmu-064262	Mus musculus	85.34	0.00e+00	744.00
IUUC-Mpu-066101	Mustela putorius furo	85.24	0.00e+00	740.00
IUUC-Mlu-067347	Myotis lucifugus	87.30	9.00e-173	599.00
IUUC-Ont-071298	Oreochromis niloticus	72.28	0.00e+00	667.00
IUUC-Oan-073219	Ornithorhynchus anatinus	88.92	6.00e-178	617.00
IUUC-Ola-086499	Oryzias latipes	71.40	0.00e+00	668.00
IUUC-Oga-088812	Otolemur garnettii	85.84	0.00e+00	706.00
IUUC-Oar-090353	Ovis aries	87.16	0.00e+00	650.00
IUUC-Psi-092988	Pelodiscus sinensis	90.00	1.00e-179	622.00
IUUC-Pfo-096268	Poecilia formosa	72.09	0.00e+00	669.00
IUUC-Pca-100597	Procavia capensis	88.38	4.00e-172	597.00
IUUC-Pva-102542	Pteropus vampyrus	72.54	1.00e-156	546.00
IUUC-Sha-106512	Sarcophilus harrisii	84.62	0.00e+00	724.00
IUUC-Sar-113233	Sorex araneus	88.38	2.00e-167	581.00
IUUC-Ssc-115781	Sus scrofa	85.13	0.00e+00	786.00
IUUC-Tgu-117384	Taeniopygia guttata	88.42	0.00e+00	655.00
IUUC-Tru-117919	Takifugu rubripes	71.61	0.00e+00	657.00
IUUC-Tsy-119275	Tarsius syrichta	85.14	5.00e-180	624.00
IUUC-Tbe-127335	Tupaia belangeri	88.62	5.00e-171	593.00
IUUC-Ttr-128554	Tursiops truncatus	88.38	2.00e-172	598.00
IUUC-Vpa-130407	Vicugna pacos	81.61	2.00e-172	598.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence