iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cre-022747

Ensembl Protein ID

EDP06639

UniProt Accession

A8IAG6; A8IAG6_CHLRE

Genbank Protein ID

EDP06639.1

Protein Name

Presenilin

Genbank Nucleotide ID

DS496114

Gene Name

PSN1; CHLREDRAFT_206031

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CHLREDRAFT_206031	EDP06639	EDP06639

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/CUE	33.64	2.00e-25	114.00	IUUC-Cel-018553
UBD/Alpha-Helix/CUE	33.89	1.00e-28	126.00	IUUC-Hsa-046455

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Chlamydomonas reinhardtii

Functional Description
(View)

Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.

Protein Sequence
(Fasta)

MRDCSSIIVL PSAVNAAGNL CFAWAFCQPV PVRVPASAMA TPSLLDDLGE EVTGIVAPVS 60
LCMAVTVLLV RLLNPEGVSS SNTVLIASIA YQEQASDSSG KKFGGALLNA LIFVAVVAGM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGAGACT GCAGCAGTAT TATCGTCCTG CCCTCTGCAG TGAACGCTGC AGGCAATTTG 60
TGTTTTGCCT GGGCTTTTTG CCAGGTGCAG GGCGGTAGCT GCATGGGATC CGCTTGCGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0472--Membrane
KW-0914--Notch signaling pathway
KW-0645--Protease
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001108--Peptidase_A22A
IPR006639--Preselin/SPP

Pfam

PF01080--Presenilin

PRINTS

PR01072--PRESENILIN

SMART

SM00730--PSN

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0005887--C:integral component of plasma membrane
GO:0005634--C:nucleus
GO:0004190--F:aspartic-type endopeptidase activity
GO:0004175--F:endopeptidase activity
GO:0007219--P:Notch signaling pathway
GO:0016485--P:protein processing

KEGG

cre:CHLREDRAFT_206031

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000686	Aegilops tauschii	74.03	6.00e-28	117.00
IUUC-Aml-001648	Ailuropoda melanoleuca	37.21	1.00e-22	98.60
IUUC-Atr-003039	Amborella trichopoda	45.33	1.00e-44	172.00
IUUC-Apl-003959	Anas platyrhynchos	33.80	5.00e-23	100.00
IUUC-Aca-005160	Anolis carolinensis	34.10	2.00e-29	121.00
IUUC-Aly-005455	Arabidopsis lyrata	43.86	7.00e-41	159.00
IUUC-Ath-006730	Arabidopsis thaliana	44.30	5.00e-42	163.00
IUUC-Ame-010686	Astyanax mexicanus	31.94	2.00e-25	108.00
IUUC-Bta-013097	Bos taurus	33.89	7.00e-29	119.00
IUUC-Bdi-014196	Brachypodium distachyon	70.93	1.00e-30	125.00
IUUC-Bol-015841	Brassica oleracea	43.97	1.00e-35	142.00
IUUC-Bra-017580	Brassica rapa	69.23	6.00e-32	129.00
IUUC-Cel-018553	Caenorhabditis elegans	33.95	5.00e-21	94.00
IUUC-Cja-018824	Callithrix jacchus	33.47	7.00e-29	119.00
IUUC-Cfa-020253	Canis familiaris	34.56	1.00e-28	119.00
IUUC-Cpo-021401	Cavia porcellus	34.72	1.00e-28	119.00
IUUC-Csa-023369	Chlorocebus sabaeus	33.89	6.00e-29	119.00
IUUC-Cho-024735	Choloepus hoffmanni	29.82	1.00e-19	89.00
IUUC-Cin-025780	Ciona intestinalis	35.05	2.00e-28	118.00
IUUC-Csv-025967	Ciona savignyi	34.11	4.00e-28	117.00
IUUC-Dre-028526	Danio rerio	34.62	3.00e-29	120.00
IUUC-Dno-029758	Dasypus novemcinctus	34.25	4.00e-24	103.00
IUUC-Dor-031127	Dipodomys ordii	35.65	2.00e-26	112.00
IUUC-Dme-031929	Drosophila melanogaster	34.56	3.00e-28	117.00
IUUC-Ete-032487	Echinops telfairi	57.83	4.00e-09	54.30
IUUC-Eca-034387	Equus caballus	33.89	2.00e-28	118.00
IUUC-Eeu-034846	Erinaceus europaeus	29.82	5.00e-22	97.10
IUUC-Fca-035396	Felis catus	34.72	7.00e-29	119.00
IUUC-Fal-036600	Ficedula albicollis	33.64	9.00e-24	102.00
IUUC-Gmo-038550	Gadus morhua	31.78	1.00e-23	102.00
IUUC-Gga-040706	Gallus gallus	34.10	3.00e-23	101.00
IUUC-Gac-042511	Gasterosteus aculeatus	32.87	1.00e-24	105.00
IUUC-Gma-043822	Glycine max	72.94	2.00e-30	125.00
IUUC-Ggo-045338	Gorilla gorilla	33.89	3.00e-29	120.00
IUUC-Hsa-046455	Homo sapiens	33.89	3.00e-29	120.00
IUUC-Hvu-047141	Hordeum vulgare	70.93	2.00e-30	125.00
IUUC-Itr-048731	Ictidomys tridecemlineatus	33.89	8.00e-29	119.00
IUUC-Lch-049638	Latimeria chalumnae	34.72	3.00e-29	120.00
IUUC-Lpe-051132	Leersia perrieri	72.09	8.00e-31	126.00
IUUC-Loc-052427	Lepisosteus oculatus	34.72	9.00e-29	119.00
IUUC-Laf-053758	Loxodonta africana	33.89	5.00e-29	120.00
IUUC-Mcc-054755	Macaca mulatta	33.89	4.00e-29	120.00
IUUC-Meu-056004	Macropus eugenii	33.03	9.00e-23	99.40
IUUC-Mtr-058392	Medicago truncatula	43.75	1.00e-33	135.00
IUUC-Mga-059466	Meleagris gallopavo	33.91	3.00e-24	104.00
IUUC-Mmr-060890	Microcebus murinus	34.72	4.00e-28	117.00
IUUC-Mdo-062122	Monodelphis domestica	34.86	3.00e-24	104.00
IUUC-Mmu-063823	Mus musculus	33.74	8.00e-29	119.00
IUUC-Mac-064858	Musa acuminata	65.93	1.00e-29	121.00
IUUC-Mpu-066181	Mustela putorius furo	34.56	5.00e-29	120.00
IUUC-Mlu-067079	Myotis lucifugus	34.40	4.00e-29	120.00
IUUC-Nle-069596	Nomascus leucogenys	33.89	5.00e-29	120.00
IUUC-Opr-070344	Ochotona princeps	34.72	5.00e-27	113.00
IUUC-Ont-071867	Oreochromis niloticus	32.41	2.00e-23	101.00
IUUC-Oan-073378	Ornithorhynchus anatinus	35.65	7.00e-30	122.00
IUUC-Ocu-074652	Oryctolagus cuniculus	34.06	2.00e-28	118.00
IUUC-Oba-075256	Oryza barthii	72.09	7.00e-31	126.00
IUUC-Obr-076302	Oryza brachyantha	72.09	7.00e-31	126.00
IUUC-Ogl-077097	Oryza glaberrima	72.09	1.00e-30	125.00
IUUC-Ogu-078570	Oryza glumaepatula	72.09	1.00e-30	125.00
IUUC-Oin-079244	Oryza indica	72.09	1.00e-30	125.00
IUUC-Olo-080484	Oryza longistaminata	72.09	2.00e-31	127.00
IUUC-Ome-081814	Oryza meridionalis	72.09	1.00e-30	125.00
IUUC-Oni-082057	Oryza nivara	72.09	1.00e-30	125.00
IUUC-Opu-084176	Oryza punctata	72.09	1.00e-30	125.00
IUUC-Oru-084618	Oryza rufipogon	72.09	1.00e-30	125.00
IUUC-Osa-085602	Oryza sativa	72.09	1.00e-30	125.00
IUUC-Ola-086707	Oryzias latipes	33.02	9.00e-27	112.00
IUUC-Olu-087811	Ostreococcus lucimarinus	43.84	6.00e-47	179.00
IUUC-Oga-088560	Otolemur garnettii	33.89	5.00e-29	120.00
IUUC-Oar-089200	Ovis aries	33.89	9.00e-29	119.00
IUUC-Ptr-090569	Pan troglodytes	34.31	3.00e-29	121.00
IUUC-Pan-091742	Papio anubis	33.89	8.00e-29	119.00
IUUC-Psi-093505	Pelodiscus sinensis	33.79	7.00e-24	103.00
IUUC-Pma-094612	Petromyzon marinus	34.26	8.00e-22	96.30
IUUC-Ppa-095431	Physcomitrella patens	46.88	7.00e-50	189.00
IUUC-Pfo-097396	Poecilia formosa	33.64	3.00e-24	104.00
IUUC-Pab-098531	Pongo abelii	33.89	6.00e-29	119.00
IUUC-Pop-099661	Populus trichocarpa	43.91	6.00e-40	156.00
IUUC-Pca-101120	Procavia capensis	33.20	5.00e-25	107.00
IUUC-Ppe-101495	Prunus persica	44.98	1.00e-42	165.00
IUUC-Pva-102934	Pteropus vampyrus	32.22	5.00e-27	113.00
IUUC-Pgr-103487	Puccinia graminis	31.82	3.10e+00	25.00
IUUC-Rno-106052	Rattus norvegicus	33.89	2.00e-28	118.00
IUUC-Sha-107045	Sarcophilus harrisii	34.86	3.00e-24	104.00
IUUC-Smo-109325	Selaginella moellendorffii	47.32	9.00e-39	152.00
IUUC-Sit-110624	Setaria italica	70.93	2.00e-30	125.00
IUUC-Sly-110865	Solanum lycopersicum	67.61	2.00e-22	95.10
IUUC-Stu-112433	Solanum tuberosum	43.10	1.00e-40	158.00
IUUC-Sar-113169	Sorex araneus	37.23	4.00e-19	87.40
IUUC-Sbi-114305	Sorghum bicolor	72.09	2.00e-31	128.00
IUUC-Ssc-115380	Sus scrofa	33.89	3.00e-30	124.00
IUUC-Tgu-117280	Taeniopygia guttata	34.26	1.00e-24	105.00
IUUC-Tru-117732	Takifugu rubripes	33.18	6.00e-24	103.00
IUUC-Tsy-119624	Tarsius syrichta	32.41	4.00e-23	100.00
IUUC-Tni-119852	Tetraodon nigroviridis	33.03	1.00e-23	102.00
IUUC-Tca-121865	Theobroma cacao	46.99	3.00e-37	147.00
IUUC-Tae-125925	Triticum aestivum	70.93	1.00e-30	125.00
IUUC-Tur-126237	Triticum urartu	70.93	1.00e-30	125.00
IUUC-Tbe-127632	Tupaia belangeri	33.89	6.00e-29	120.00
IUUC-Ttr-129008	Tursiops truncatus	33.89	3.00e-27	114.00
IUUC-Vpa-130625	Vicugna pacos	42.45	3.00e-18	84.30
IUUC-Vvi-131312	Vitis vinifera	48.04	2.00e-37	148.00
IUUC-Xtr-132756	Xenopus tropicalis	34.25	3.00e-28	117.00
IUUC-Xma-133377	Xiphophorus maculatus	33.64	4.00e-24	103.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence