iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020344

Ensembl Protein ID

ENSCAFP00000009752.3

UniProt Accession

F1PY01; F1PY01_CANLF

Genbank Protein ID

ENSCAFP00000009752

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03010889

Gene Name

EML4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000006510.3	ENSCAFT00000010521.3	ENSCAFP00000009752.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-18	65.9	719	755

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH++ +t l++ +d +++ s s+D  i  WD+ +g +
   Q: 719  GHSSYITHLDWsPDnKYIMSNSGDYEILYWDIPSGCK 755
           8***********998****************988865 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MDGFAGSLDD SISAASTSDV QDRLSALELR VQQQEDEITV LKAALADVLR RLAISEDHVA 60
SVKKSVPSKG QPGLREAISM SCITNGSGAN RKPSHTSSVA IARKETLSSA AKSGTEKKKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGAGTCGGA AGCGTGACGG CGTGCGCGGG GGCGGGGCTA CCGCTGCGCG CGGGCGCGGG 60
GGCGGGGCGC GGCGCGGCGT TCGCGGCTGC TGCCTGGGAG GGAGGCCGGG CAGGCGGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0016020--C:membrane
GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001465	Ailuropoda melanoleuca	97.45	0.00e+00	1915.00
IUUC-Apl-003728	Anas platyrhynchos	89.68	0.00e+00	1383.00
IUUC-Aca-004921	Anolis carolinensis	77.70	0.00e+00	1499.00
IUUC-Ame-011846	Astyanax mexicanus	80.07	0.00e+00	1419.00
IUUC-Bta-013457	Bos taurus	94.59	0.00e+00	1825.00
IUUC-Cel-018623	Caenorhabditis elegans	29.55	2.00e-82	300.00
IUUC-Cja-019963	Callithrix jacchus	91.85	0.00e+00	1734.00
IUUC-Cpo-022426	Cavia porcellus	91.93	0.00e+00	1754.00
IUUC-Csa-023822	Chlorocebus sabaeus	93.58	0.00e+00	1785.00
IUUC-Cho-024398	Choloepus hoffmanni	98.22	0.00e+00	761.00
IUUC-Dno-029822	Dasypus novemcinctus	93.53	0.00e+00	1759.00
IUUC-Ete-032548	Echinops telfairi	76.50	0.00e+00	1325.00
IUUC-Eca-033255	Equus caballus	95.21	0.00e+00	1900.00
IUUC-Eeu-034609	Erinaceus europaeus	84.31	4.00e-150	525.00
IUUC-Fca-035637	Felis catus	94.86	0.00e+00	1870.00
IUUC-Fal-037030	Ficedula albicollis	85.96	0.00e+00	1608.00
IUUC-Gmo-038662	Gadus morhua	80.34	0.00e+00	1250.00
IUUC-Gga-041202	Gallus gallus	89.17	0.00e+00	1650.00
IUUC-Gac-041394	Gasterosteus aculeatus	74.02	0.00e+00	1338.00
IUUC-Ggo-044734	Gorilla gorilla	93.48	0.00e+00	1746.00
IUUC-Hsa-046616	Homo sapiens	92.14	0.00e+00	1759.00
IUUC-Lch-050585	Latimeria chalumnae	77.40	0.00e+00	1468.00
IUUC-Loc-052753	Lepisosteus oculatus	80.18	0.00e+00	1445.00
IUUC-Laf-054189	Loxodonta africana	90.71	0.00e+00	1746.00
IUUC-Mcc-055697	Macaca mulatta	92.44	0.00e+00	1774.00
IUUC-Mmr-060888	Microcebus murinus	91.88	0.00e+00	1707.00
IUUC-Mdo-062025	Monodelphis domestica	86.00	0.00e+00	1531.00
IUUC-Mmu-063591	Mus musculus	89.10	0.00e+00	1755.00
IUUC-Mpu-065718	Mustela putorius furo	95.26	0.00e+00	1879.00
IUUC-Mlu-068068	Myotis lucifugus	94.70	0.00e+00	1834.00
IUUC-Nle-069281	Nomascus leucogenys	93.07	0.00e+00	1699.00
IUUC-Opr-070938	Ochotona princeps	70.32	0.00e+00	1237.00
IUUC-Ont-071488	Oreochromis niloticus	72.10	0.00e+00	1298.00
IUUC-Oan-073561	Ornithorhynchus anatinus	74.16	0.00e+00	1002.00
IUUC-Ocu-074399	Oryctolagus cuniculus	93.64	0.00e+00	1787.00
IUUC-Ola-086551	Oryzias latipes	71.38	0.00e+00	1290.00
IUUC-Oga-088783	Otolemur garnettii	93.35	0.00e+00	1835.00
IUUC-Oar-089716	Ovis aries	94.59	0.00e+00	1786.00
IUUC-Ptr-090942	Pan troglodytes	90.12	0.00e+00	1703.00
IUUC-Pan-091831	Papio anubis	91.73	0.00e+00	1772.00
IUUC-Psi-093094	Pelodiscus sinensis	86.74	0.00e+00	1685.00
IUUC-Pfo-097066	Poecilia formosa	68.78	0.00e+00	1254.00
IUUC-Pab-098351	Pongo abelii	93.58	0.00e+00	1748.00
IUUC-Pva-102783	Pteropus vampyrus	84.40	0.00e+00	1602.00
IUUC-Rno-105412	Rattus norvegicus	89.62	0.00e+00	1645.00
IUUC-Sha-106597	Sarcophilus harrisii	86.19	0.00e+00	1663.00
IUUC-Sar-113748	Sorex araneus	75.94	0.00e+00	1371.00
IUUC-Ssc-115740	Sus scrofa	94.39	0.00e+00	1787.00
IUUC-Tgu-116696	Taeniopygia guttata	87.97	0.00e+00	1598.00
IUUC-Tru-118506	Takifugu rubripes	75.00	0.00e+00	1348.00
IUUC-Tsy-119375	Tarsius syrichta	83.58	0.00e+00	1596.00
IUUC-Tni-120392	Tetraodon nigroviridis	70.26	0.00e+00	1220.00
IUUC-Tbe-127468	Tupaia belangeri	86.56	0.00e+00	1639.00
IUUC-Ttr-128746	Tursiops truncatus	89.70	0.00e+00	1823.00
IUUC-Vpa-130697	Vicugna pacos	93.37	0.00e+00	1806.00
IUUC-Xtr-132731	Xenopus tropicalis	81.46	0.00e+00	1600.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence