iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118557

UUCD1 version

UUC-TaR-00180

Ensembl Protein ID

ENSTRUP00000009618.1

UniProt Accession

H2SB40; H2SB40_TAKRU

Protein Name

Uncharacterized protein

Gene Name

rnf139

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000004057.1	ENSTRUT00000009673.1	ENSTRUP00000009618.1
ENSTRUG00000004057.1	ENSTRUT00000009674.1	ENSTRUP00000009619.1
ENSTRUG00000004057.1	ENSTRUT00000009675.1	ENSTRUP00000009620.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.70e-07	32.9	545	583

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           CaiC+++f+   +++pC H fh+ Cl kw       + +++CP C
   Q: 545  CAICYQEFSSSARITPCHHYFHTLCLRKW------LYIQDTCPMC 583
           ********999******************......********** PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MATAQARIGH QVFVVLDVVL RVPCIFILDA IFNSHYDAGS GWAGSVAKLA IRITGVFISS 60
VVLLLSQKAL FKFYTLFCAA LLGMAAVLFN YYATSHSDIY SYYYNAALGF HLLPKNASTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGCTTAAT CGATTGAGCT TCAGGCTGAG GTGACCAGTC CGACAGCTGA TTACCAACAC 60
CTGATTACCA ACACCTGATG ACCTGCTTTC ACTGGCAGCA CAGTCGAAGG AGAAGCCTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025754--TRC8_N_dom
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13705--TRC8_N
PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002401	Ailuropoda melanoleuca	66.02	0.00e+00	881.00
IUUC-Apl-004214	Anas platyrhynchos	74.50	0.00e+00	829.00
IUUC-Aca-005326	Anolis carolinensis	69.67	0.00e+00	847.00
IUUC-Ame-011687	Astyanax mexicanus	75.62	0.00e+00	996.00
IUUC-Bta-013394	Bos taurus	66.77	0.00e+00	909.00
IUUC-Cja-019499	Callithrix jacchus	66.17	0.00e+00	901.00
IUUC-Cfa-020357	Canis familiaris	66.32	0.00e+00	888.00
IUUC-Cpo-021924	Cavia porcellus	67.85	0.00e+00	879.00
IUUC-Csa-023513	Chlorocebus sabaeus	65.72	0.00e+00	894.00
IUUC-Cho-024285	Choloepus hoffmanni	61.10	0.00e+00	775.00
IUUC-Cin-025223	Ciona intestinalis	52.61	8.00e-74	270.00
IUUC-Csv-026018	Ciona savignyi	48.26	8.00e-68	250.00
IUUC-Dre-028660	Danio rerio	75.30	0.00e+00	909.00
IUUC-Dno-029463	Dasypus novemcinctus	70.20	5.00e-104	371.00
IUUC-Dor-030728	Dipodomys ordii	68.06	0.00e+00	843.00
IUUC-Dme-032186	Drosophila melanogaster	43.87	3.00e-99	356.00
IUUC-Ete-032368	Echinops telfairi	65.47	0.00e+00	885.00
IUUC-Eca-034325	Equus caballus	66.47	0.00e+00	884.00
IUUC-Fca-035537	Felis catus	66.98	0.00e+00	863.00
IUUC-Fal-037459	Ficedula albicollis	73.87	0.00e+00	804.00
IUUC-Gmo-039442	Gadus morhua	82.22	4.00e-103	369.00
IUUC-Gga-041071	Gallus gallus	71.24	0.00e+00	845.00
IUUC-Gac-042483	Gasterosteus aculeatus	81.28	0.00e+00	1110.00
IUUC-Ggo-044672	Gorilla gorilla	65.87	0.00e+00	894.00
IUUC-Hsa-045836	Homo sapiens	66.02	0.00e+00	879.00
IUUC-Itr-048588	Ictidomys tridecemlineatus	67.12	0.00e+00	922.00
IUUC-Lch-050073	Latimeria chalumnae	71.79	0.00e+00	972.00
IUUC-Loc-052908	Lepisosteus oculatus	77.27	0.00e+00	1041.00
IUUC-Laf-053519	Loxodonta africana	65.97	0.00e+00	912.00
IUUC-Mpo-057601	Magnaporthe poae	34.04	4.00e-08	53.10
IUUC-Mga-059922	Meleagris gallopavo	73.56	0.00e+00	825.00
IUUC-Mvi-060396	Microbotryum violaceum	40.00	2.00e-05	44.70
IUUC-Mmr-061452	Microcebus murinus	65.37	0.00e+00	881.00
IUUC-Mdo-062412	Monodelphis domestica	66.27	0.00e+00	892.00
IUUC-Mmu-063147	Mus musculus	65.75	0.00e+00	902.00
IUUC-Mpu-065929	Mustela putorius furo	65.87	0.00e+00	885.00
IUUC-Mlu-067899	Myotis lucifugus	65.77	0.00e+00	886.00
IUUC-Nle-070083	Nomascus leucogenys	65.87	0.00e+00	895.00
IUUC-Opr-070461	Ochotona princeps	66.07	0.00e+00	898.00
IUUC-Ont-072256	Oreochromis niloticus	80.68	0.00e+00	1127.00
IUUC-Oan-073150	Ornithorhynchus anatinus	70.00	0.00e+00	787.00
IUUC-Ocu-073748	Oryctolagus cuniculus	65.22	0.00e+00	870.00
IUUC-Oga-088565	Otolemur garnettii	66.72	0.00e+00	909.00
IUUC-Oar-089432	Ovis aries	67.61	0.00e+00	882.00
IUUC-Ptr-091422	Pan troglodytes	65.87	0.00e+00	892.00
IUUC-Pan-092331	Papio anubis	65.72	0.00e+00	892.00
IUUC-Psi-092933	Pelodiscus sinensis	73.21	0.00e+00	828.00
IUUC-Pfo-097466	Poecilia formosa	79.62	0.00e+00	1118.00
IUUC-Pab-098702	Pongo abelii	65.87	0.00e+00	895.00
IUUC-Pca-100125	Procavia capensis	69.55	0.00e+00	888.00
IUUC-Pva-102628	Pteropus vampyrus	66.97	0.00e+00	890.00
IUUC-Rno-104886	Rattus norvegicus	65.26	0.00e+00	902.00
IUUC-Sha-106702	Sarcophilus harrisii	65.23	0.00e+00	887.00
IUUC-Ssc-116164	Sus scrofa	66.32	0.00e+00	908.00
IUUC-Tgu-116829	Taeniopygia guttata	71.04	0.00e+00	824.00
IUUC-Tsy-119399	Tarsius syrichta	69.16	9.00e-152	529.00
IUUC-Tni-120006	Tetraodon nigroviridis	73.41	0.00e+00	953.00
IUUC-Tbe-127664	Tupaia belangeri	66.27	0.00e+00	884.00
IUUC-Ttr-129144	Tursiops truncatus	65.67	0.00e+00	907.00
IUUC-Vpa-130226	Vicugna pacos	67.11	0.00e+00	906.00
IUUC-Xtr-132461	Xenopus tropicalis	64.84	0.00e+00	832.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence