iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-119928

Ensembl Protein ID

ENSTNIP00000001166.1

UniProt Accession

H3BYV0; H3BYV0_TETNG

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000016905.1	ENSTNIT00000002585.1	ENSTNIP00000001166.1
ENSTNIG00000016905.1	ENSTNIT00000003018.1	ENSTNIP00000003608.1
ENSTNIG00000016905.1	ENSTNIT00000020254.1	ENSTNIP00000020023.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.40e-14	51.7	66	121

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +++v ++y+y++++d++L ++kGd++++i  ++ d +W  +++ ++g+rG +P nF++
   Q: 66   DNLVVAIYSYNPKHDGDLGFEKGDKLKII--NKDDSEWYLAESLTTGQRGYIPYNFIA 121
           5789*************************..78899********************96 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MGCNCSSDYS DAEWIENLDE ICEHCNCPIA PQSCNPVKYL CRPDLKYTDQ LIGFSQLSPP 60
SSPLPDNLVV AIYSYNPKHD GDLGFEKGDK LKIINKDDSE WYLAESLTTG QRGYIPYNFI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGATGCA ACTGCAGTTC AGATTATTCC GACGCCGAGT GGATTGAGAA CCTGGATGAA 60
ATCTGTGAAC ACTGCAACTG TCCGATAGCT CCTCAGTCCT GCAACCCAGT GAGTGTCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-010831	Astyanax mexicanus	65.56	4.00e-173	600.00
IUUC-Dre-028005	Danio rerio	65.42	0.00e+00	660.00
IUUC-Gmo-038984	Gadus morhua	68.16	0.00e+00	714.00
IUUC-Gac-041854	Gasterosteus aculeatus	76.37	0.00e+00	807.00
IUUC-Lch-049568	Latimeria chalumnae	64.33	0.00e+00	678.00
IUUC-Loc-052222	Lepisosteus oculatus	67.63	0.00e+00	687.00
IUUC-Meu-056879	Macropus eugenii	60.19	0.00e+00	638.00
IUUC-Ont-071711	Oreochromis niloticus	77.15	0.00e+00	781.00
IUUC-Ola-087000	Oryzias latipes	72.21	0.00e+00	738.00
IUUC-Pfo-096542	Poecilia formosa	74.61	0.00e+00	785.00
IUUC-Tru-118559	Takifugu rubripes	79.38	0.00e+00	825.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence