iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001345

Ensembl Protein ID

ENSAMEP00000009814.1

UniProt Accession

G1LRX7; G1LRX7_AILME

Genbank Protein ID

ENSAMEP00000009814

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01137300

Gene Name

GRB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000009339.1	ENSAMET00000010241.1	ENSAMEP00000009814.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.10e-25	88.0	132	189

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +  +vq+l+d+++q+d+eL +++Gd+++v+  ++ d +W+kg    +g+ G+fP n+v+ ++
   Q: 132  QPTYVQALFDFDPQEDGELGFRRGDFIHVM--DNSDPNWWKG--ACHGQTGMFPRNYVTPVN 189
           5689*************************9..9*********..8**************997 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

QVLNEECDQN WYKAELNGKD GFIPKNYIEM KPHPWFFGKI PRAKAEEMLS KQRHDGAFLI 60
RESESAPGDF SLSVKFGNDV QHFKVLRDGA GKYFLWVVKF NSLNELVDYH RSTSVSRNQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGTTTTGA ATGAAGAATG TGATCAGAAC TGGTACAAGG CAGAACTCAA TGGGAAAGAT 60
GGCTTCATTC CCAAGAATTA TATAGAAATG AAACCACATC CGTAAGTTGG ACTCTACTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0008180--C:COP9 signalosome
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0070436--C:Grb2-EGFR complex
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0012506--C:vesicle membrane
GO:0003723--F:RNA binding
GO:0048646--P:anatomical structure formation involved in morphogenesis
GO:0060670--P:branching involved in labyrinthine layer morphogenesis
GO:0030154--P:cell differentiation
GO:0071479--P:cellular response to ionizing radiation
GO:0008286--P:insulin receptor signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:2000379--P:positive regulation of reactive oxygen species metabolic process
GO:0009967--P:positive regulation of signal transduction
GO:0031623--P:receptor internalization
GO:0043408--P:regulation of MAPK cascade
GO:0042770--P:signal transduction in response to DNA damage

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003322	Anas platyrhynchos	97.38	3.00e-111	393.00
IUUC-Aca-005193	Anolis carolinensis	96.88	6.00e-112	395.00
IUUC-Ame-010929	Astyanax mexicanus	92.19	4.00e-107	380.00
IUUC-Bta-012932	Bos taurus	99.48	3.00e-114	404.00
IUUC-Cja-019225	Callithrix jacchus	99.48	3.00e-114	404.00
IUUC-Cfa-020887	Canis familiaris	99.48	3.00e-114	404.00
IUUC-Cpo-022488	Cavia porcellus	99.48	3.00e-114	404.00
IUUC-Csa-023326	Chlorocebus sabaeus	99.48	3.00e-114	404.00
IUUC-Cho-024953	Choloepus hoffmanni	100.00	1.00e-87	315.00
IUUC-Cin-025144	Ciona intestinalis	60.11	4.00e-61	227.00
IUUC-Csv-026210	Ciona savignyi	59.68	3.00e-60	224.00
IUUC-Dre-028403	Danio rerio	94.27	1.00e-109	388.00
IUUC-Dno-029120	Dasypus novemcinctus	98.96	2.00e-113	400.00
IUUC-Dor-030763	Dipodomys ordii	99.48	3.00e-114	404.00
IUUC-Dme-031741	Drosophila melanogaster	63.64	1.00e-66	245.00
IUUC-Ete-032354	Echinops telfairi	65.45	2.00e-67	248.00
IUUC-Eca-033222	Equus caballus	99.48	3.00e-114	404.00
IUUC-Eeu-034513	Erinaceus europaeus	69.79	4.00e-73	267.00
IUUC-Fca-036294	Felis catus	99.48	3.00e-114	404.00
IUUC-Fal-037130	Ficedula albicollis	95.83	2.00e-110	390.00
IUUC-Gmo-039546	Gadus morhua	93.23	3.00e-108	383.00
IUUC-Gga-041139	Gallus gallus	96.88	5.00e-112	396.00
IUUC-Gac-041968	Gasterosteus aculeatus	95.31	4.00e-110	390.00
IUUC-Ggo-044562	Gorilla gorilla	99.48	3.00e-114	404.00
IUUC-Hsa-046730	Homo sapiens	99.48	3.00e-114	404.00
IUUC-Itr-049025	Ictidomys tridecemlineatus	99.48	3.00e-114	404.00
IUUC-Lch-050230	Latimeria chalumnae	95.45	5.00e-72	264.00
IUUC-Loc-052723	Lepisosteus oculatus	95.83	2.00e-110	391.00
IUUC-Laf-053774	Loxodonta africana	97.92	5.00e-113	399.00
IUUC-Mcc-054603	Macaca mulatta	99.48	3.00e-114	404.00
IUUC-Meu-056173	Macropus eugenii	94.30	9.00e-89	319.00
IUUC-Mga-059950	Meleagris gallopavo	96.88	5.00e-112	396.00
IUUC-Mmr-060878	Microcebus murinus	99.48	3.00e-114	404.00
IUUC-Mdo-062454	Monodelphis domestica	96.88	5.00e-112	396.00
IUUC-Mmu-063913	Mus musculus	98.96	5.00e-114	402.00
IUUC-Mpu-066125	Mustela putorius furo	99.48	3.00e-114	404.00
IUUC-Mlu-068007	Myotis lucifugus	99.48	3.00e-114	404.00
IUUC-Nle-069101	Nomascus leucogenys	99.48	3.00e-114	404.00
IUUC-Opr-071075	Ochotona princeps	99.48	3.00e-114	404.00
IUUC-Ont-072253	Oreochromis niloticus	90.10	7.00e-105	372.00
IUUC-Ocu-074583	Oryctolagus cuniculus	99.48	3.00e-114	404.00
IUUC-Ola-086586	Oryzias latipes	96.18	9.00e-72	263.00
IUUC-Oga-089047	Otolemur garnettii	99.48	3.00e-114	404.00
IUUC-Oar-089904	Ovis aries	91.19	6.00e-103	366.00
IUUC-Ptr-090678	Pan troglodytes	99.48	3.00e-114	404.00
IUUC-Pan-092090	Papio anubis	99.48	3.00e-114	404.00
IUUC-Psi-093765	Pelodiscus sinensis	96.35	2.00e-111	394.00
IUUC-Pma-094650	Petromyzon marinus	84.90	7.00e-98	349.00
IUUC-Pfo-096131	Poecilia formosa	93.75	5.00e-109	386.00
IUUC-Pab-098709	Pongo abelii	99.48	3.00e-114	404.00
IUUC-Pca-100581	Procavia capensis	98.95	9.00e-113	398.00
IUUC-Pva-103066	Pteropus vampyrus	99.48	3.00e-114	404.00
IUUC-Rno-105224	Rattus norvegicus	99.48	3.00e-114	404.00
IUUC-Sce-106302	Saccharomyces cerevisiae	51.85	1.00e-15	76.30
IUUC-Sha-107247	Sarcophilus harrisii	97.91	1.00e-111	395.00
IUUC-Sar-113277	Sorex araneus	99.37	2.00e-92	331.00
IUUC-Ssc-115478	Sus scrofa	99.48	3.00e-114	404.00
IUUC-Tgu-117479	Taeniopygia guttata	95.83	2.00e-110	390.00
IUUC-Tru-118451	Takifugu rubripes	82.84	7.00e-92	329.00
IUUC-Tsy-119029	Tarsius syrichta	91.85	2.00e-68	250.00
IUUC-Tbe-128097	Tupaia belangeri	98.96	2.00e-113	400.00
IUUC-Ttr-128871	Tursiops truncatus	99.24	4.00e-75	273.00
IUUC-Vpa-130754	Vicugna pacos	99.48	3.00e-114	404.00
IUUC-Xtr-132275	Xenopus tropicalis	90.69	5.00e-108	383.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence