iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.10e-10	41.5	54	100

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClkls.veeelpnsekwiCpkCr 52
           ++C  C+egg+    l++C++C + fH +C+ ++  ee+ p+ + w C +Cr
   Q: 54   DYCDACEEGGN----LLCCDRCPSSFHLQCHDPPlSEEDIPSGQ-WLCHSCR 100
           68999999999....******************97788899996.******8 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSKLDQDPNA SLSIMEQIKQ LIRPPPNEDE KMMQRSTNTK HPYYRRPGRG HNHDYCDACE 60
EGGNLLCCDR CPSSFHLQCH DPPLSEEDIP SGQWLCHSCR MSKLSQPPAS SSKASSVERV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCATTCGCTC GTCGGATGCG CAGGGCTGGA CAACCGACAC TGCGCCCGCC TCCGTCGCCA 60
AGTGAAGTCG CTCCGAGATT GATTGTGTAC ACCGGATAAG AGGAGCGAGC GAAAAAGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000253--FHA_dom
IPR031966--PHF12_MRG-bd
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50006--FHA_DOMAIN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00628--PHD
PF16737--PHF12_MRG_bd

SMART

SM00249--PHD

Gene Ontology

GO:0070822--C:Sin3-type complex
GO:0003682--F:chromatin binding
GO:0042393--F:histone binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003712--F:transcription cofactor activity
GO:0008270--F:zinc ion binding
GO:0006355--P:regulation of transcription, DNA-templated

KEGG

dme:Dmel_CG3815

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007848	Ashbya gossypii	35.63	5.00e-14	72.00
IUUC-Afu-008819	Aspergillus fumigatus	43.55	2.00e-12	67.00
IUUC-Bgr-012025	Blumeria graminis	37.04	3.00e-08	53.90
IUUC-Bci-013636	Botrytis cinerea	44.00	1.00e-09	58.50
IUUC-Cel-018210	Caenorhabditis elegans	23.88	3.00e-21	97.10
IUUC-Cin-025146	Ciona intestinalis	36.59	1.00e-29	125.00
IUUC-Cne-026966	Cryptococcus neoformans	50.94	2.00e-12	66.60
IUUC-Dre-027802	Danio rerio	35.32	7.00e-65	241.00
IUUC-Dse-031258	Dothistroma septosporum	51.92	7.00e-10	58.90
IUUC-Fso-038262	Fusarium solani	41.67	1.00e-07	52.00
IUUC-Gmo-038603	Gadus morhua	43.75	2.00e-42	167.00
IUUC-Ggr-039977	Gaeumannomyces graminis	45.83	2.00e-10	61.60
IUUC-Lch-050540	Latimeria chalumnae	32.47	3.00e-66	246.00
IUUC-Loc-052037	Lepisosteus oculatus	43.56	2.00e-41	163.00
IUUC-Mpo-057458	Magnaporthe poae	45.83	1.00e-10	62.00
IUUC-Mvi-060276	Microbotryum violaceum	32.26	2.00e-11	63.50
IUUC-Nfi-068496	Neosartorya fischeri	45.16	7.00e-13	68.90
IUUC-Ncr-068727	Neurospora crassa	47.06	1.00e-11	65.50
IUUC-Ont-072294	Oreochromis niloticus	37.77	8.00e-44	171.00
IUUC-Oga-089177	Otolemur garnettii	37.75	8.00e-67	248.00
IUUC-Sja-107964	Schizosaccharomyces japonicus	43.33	4.00e-14	72.00
IUUC-Spo-108017	Schizosaccharomyces pombe	48.15	2.00e-14	73.60
IUUC-Tre-121959	Trichoderma reesei	37.74	1.00e-08	55.10
IUUC-Tvi-122553	Trichoderma virens	41.67	2.00e-08	54.70
IUUC-Tme-127204	Tuber melanosporum	48.98	4.00e-12	66.60
IUUC-Vda-129988	Verticillium dahliae	34.18	5.00e-08	53.10
IUUC-Xtr-132518	Xenopus tropicalis	36.61	2.00e-60	226.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence