iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-089177

Ensembl Protein ID

ENSOGAP00000007119.2

UniProt Accession

H0WXE2; H0WXE2_OTOGA

Genbank Protein ID

ENSOGAP00000007119

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03132738

Gene Name

PHF12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000007952.2	ENSOGAT00000007954.2	ENSOGAP00000007119.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.60e-08	34.6	58	103

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClkls.veeelpnsekwiCpkCr 52
           +C  C+egg+    l++C++C  +fH +C +++  ee lp  e w+C +C+
   Q: 58   SCDSCKEGGD----LLCCDHCPAAFHLQCCNPPlSEEMLPPGE-WMCHRCT 103
           6888999999....*******************7778888887.******7 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MWEKMETKTI VYDLDTSGGL MEQIQALLAP PKTDETEKRS RKPEKEPRRS GRATNHDSCD 60
SCKEGGDLLC CDHCPAAFHL QCCNPPLSEE MLPPGEWMCH RCTVRRKKRE QKKELGHVNG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAATGTGGGA GAAAATGGAG ACCAAGACGA TCGTGTACGA CTTGGACACG TCGGGGGGGC 60
TGATGGAGGT AAGACTGGCC CTCCTCATCC CCTTCCCCCA GCGCCGGGAG AGAACCTCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000253--FHA_dom
IPR031966--PHF12_MRG-bd
IPR008984--SMAD_FHA_domain
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50006--FHA_DOMAIN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00628--PHD
PF16737--PHF12_MRG_bd

SMART

SM00249--PHD

Gene Ontology

GO:0016580--C:Sin3 complex
GO:0017053--C:transcriptional repressor complex
GO:0035091--F:phosphatidylinositol binding
GO:0001106--F:RNA polymerase II transcription corepressor activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007848	Ashbya gossypii	50.00	4.00e-13	69.70
IUUC-Cin-025146	Ciona intestinalis	38.52	5.00e-42	166.00
IUUC-Dre-027802	Danio rerio	59.36	5.00e-176	611.00
IUUC-Dme-031758	Drosophila melanogaster	38.24	8.00e-68	251.00
IUUC-Fox-038014	Fusarium oxysporum	28.97	4.00e-09	57.80
IUUC-Fso-038262	Fusarium solani	40.38	3.00e-09	58.20
IUUC-Gmo-038603	Gadus morhua	47.61	0.00e+00	635.00
IUUC-Lch-050540	Latimeria chalumnae	63.87	0.00e+00	1143.00
IUUC-Loc-052037	Lepisosteus oculatus	61.63	0.00e+00	1077.00
IUUC-Mvi-060276	Microbotryum violaceum	42.86	4.00e-11	63.20
IUUC-Ont-072294	Oreochromis niloticus	67.70	2.00e-105	377.00
IUUC-Sja-107964	Schizosaccharomyces japonicus	44.23	2.00e-11	63.50
IUUC-Xtr-132518	Xenopus tropicalis	65.42	0.00e+00	1103.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence