iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-086960

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

BAAF04028328

Gene Name

smurf1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000013636.1	ENSORLT00000017107.1	ENSORLP00000017106.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	7.80e-95	318.4	553	698

Active Site

Position(s)	Description	Evidence
667	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 197  fneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk.. 283
           ++e+ip++ll+ F+++elel+i G  +id+ d+k +t+ k+ +t++s++++wFw+++e+fs+e r ++LqFvTgs r+Pl+Gf++l+  
   Q: 553  LRELIPQHLLKPFDHKELELIIGGLGKIDLADWKTNTRLKH-CTSESNVVRWFWQAVEAFSEERRGRLLQFVTGSTRVPLQGFKALQgs 640
           579************************************99.*********************************************** PP
   S: 284  .....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
                prlf+i+  da++d+lP+++TCfn++++P+Y+s+e+l+ekLl+A+eet gF +
   Q: 641  tgsagPRLFTIHLiDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAV 698
           *************99999**************************************76 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MSNPGSRRNG SSIKIRLTVL CAKNLAKKDF FRLPDPFAKV VVDGSGQCHS TDTVKSTLDP 60
KWNQHYDLYI GKTDSITISI WNHKKIHKRQ GAGFLGCIRL LSNAISRLKD TGYQRLDLCK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAATGTTCTC CCGTGTTGTT GGATTTAGAA GGAGCGCAGG ACTTTGCGGC GGAATTATGT 60
CTTTTTATCC ATGAAGAAAA CAGCCCTCGT CTTCTTGTAG TGAAGTCTTT GCGGTCCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-010901	Astyanax mexicanus	79.55	0.00e+00	1174.00
IUUC-Cho-024963	Choloepus hoffmanni	69.23	0.00e+00	630.00
IUUC-Dre-028341	Danio rerio	79.42	0.00e+00	1176.00
IUUC-Gac-041707	Gasterosteus aculeatus	85.24	0.00e+00	1221.00
IUUC-Loc-052628	Lepisosteus oculatus	74.32	0.00e+00	1154.00
IUUC-Ont-072265	Oreochromis niloticus	82.82	0.00e+00	1249.00
IUUC-Pfo-097203	Poecilia formosa	84.04	0.00e+00	1218.00
IUUC-Tru-117843	Takifugu rubripes	81.32	0.00e+00	1209.00
IUUC-Tni-120037	Tetraodon nigroviridis	80.05	0.00e+00	1138.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence